Michael Mauer

Current Position (s): Professor of Pediatrics
Co-Director Peditric Nephrology
Director Pediatric Transplantation

Curriculum Vitae
General Information (pdf)
Ref. Articles (pdf)
Abstracts (pdf)
Book Chapters (pdf)
Review Articles (pdf)

Research Interests and areas of potential collaboration:
diabetic nephropathy
molecular and genetic aspects of diabetic complications
pancreas transplantation
diabetic nephropathy treatment trials
stereology

1. Treatment trial of renin/angiotensin system blockade in preclinical diabetic nephropathy (DN)
2. Natural history of DN
3. Molecular biology of skin fibroblast behavior and DN  genetic risk
4. DN in sib pairs
5. Pancreas transplant and DN

Selected publications:

Caramori ML, Fioretto P, Mauer M.  In search of an early and precise predictor of diabetic nephropathy risk.  Diabetes (in press).

Fioretto P, Steffes MW, Barbosa J, Rich SS, Mauer M.  Is diabetic nephropathy inherited?  Studies of glomerular structure in type 1 diabetic sibling pairs.  Diabetes 48:865-869, 1999.

Trevisan R, Fioretto P, Barbosa J, Mauer M.  Insulin-dependent diabetic sibling pairs are concordant for sodium-hydrogen antiport activity.  Kidney Int 55:2383-2389, 1999.

Fioretto P, Steffes MW, Sutherland DER, Goetz FC, Mauer M.  Reversal of lesions of diabetic nephropathy after pancreas transplantation.  New Engl J Med 339:69-75, 1998

Brito PL, Fioretto P, Drummond K, Kim Y, Steffes MW, Basgen JM, Sisson-Ross S,   Mauer M.  Proximal tubular basement membrane width in insulin-dependent diabetes mellitus.  Kidney Int 53:754-761, 1998.

Jin DK, Kim Y, Mauer M, Fioretto P, Vats A, Fish AJ.  Relationships of cell proliferation and expression of integrin subunits and type I collagen in skin fibroblasts with renal lesions in patients with IDDM.  Am J Kidney Dis 31(2):293-300, 1998.

Fioretto P, Mauer M, Brocco E, Velussi M, Frigato F, Muollo B, Sambataro M, Abaterusso C, Baggio B, Crepaldi G, Nosadini R.  Patterns of renal injury in NIDDM patients with microalbuminuria.  Diabetologia 39:1569-1576, 1996.

Fioretto P, Steffes MW, Sutherland DER, Mauer M.  Sequential renal biopsies in insulin-dependent diabetic patients:  Structural factors associated with clinical progression.  Kidney Int 48:1929-1935, 1995.

Yagame M, Kim Y, Zhu D, Suzuki D, Eguchi K, Nomoto Y, Sakai H, Groppoli T, Steffes MW, Mauer SM.  Differential distribution of type IV collagen chains in patients with diabetic nephropathy in non-insulin-dependent diabetes mellitus.  Nephron 70:42-48, 1995.

Fioretto P, Steffes MW, Mauer SM.  Glomerular structure in non-proteinuric insulin-dependent diabetic patients with various levels of albuminuria.  Diabetes 43:1358-1364, 1994.

Barbosa J, Steffes MW, Sutherland DER, Connett JE, Rao KV, Mauer SM.  Effect of glycemic control on early diabetic renal lesions.  A 5-year randomized controlled clinical trial of insulin-dependent diabetic kidney transplant recipients.  J Am Med Assoc 272:600-606, 1994.

Zhu D, Kim Y, Steffes MW, Groppoli TJ, Butkowski RJ, Mauer SM.  Glomerular distribution of type IV collagen in diabetes by high resolution quantitative immunochemistry.  Kidney Int 45:425-433, 1994.