Antoinette Moran, M.D.

Current Position (s): Associate Professor, Department of Pediatrics, University of Minnesota, Minneapolis

Curriculum Vitae (pdf)

Research Interests and areas of potential collaboration:

Selected publications:

1.  Moran A, MacDonald J. Eight cases of childhood stroke. Minnesota Medicine  68:675-7, 1985.

2.  Klein DJ, Brown DM, Moran A, Oegema TR, Platt J. Chondroitin sulfate proteoglycan synthesis and reutilization of beta-D-xyloside initiated chondroitin/dermatan sulfate glycosaminoglycans in fetal kidney branching morphogenesis. Dev. Biol. 133:515-28. 1989.

3.  Moran A, Asa SL, Horvath E, Kovacs K, Horvath E, Winger W, Sagman U, Reubi JC, Wilson CB, Larson R, Pescovitz OH.  Gigantism due to pituitary mammostomatotroph hyperplasia. N Engl J Med  323: 322-327. 1990

4.  Diem P, Redmon JB, Abid M, Moran A, Sutherland DER, Halter JB, Robertson RP.  Glucagon, catecholamine and pancreatic polypeptide secretion in type I diabetic recipients of pancreas allografts. J Clin Invest  86:2008-2013. 1990.

5.  Moran A, Diem P, Levitt M, Klein DJ, Robertson RP.  Pancreatic endocrine function in cystic fibrosis. J Pediatr  118: 715-23, 1991.

6.  Moran A, Brown DM, Kim YK, Klein DJ. The effects of IGF-I and hyperglycemia on protein and proteoglycan synthesis by human fetal mesangial cells. Diabetes.  40:1346-54, 1991.

7.  Shenker A, Weinstein LS, Moran A, Pescovitz OH, Charest NJ, Van Wyk JJ, Merino MJ, Feuillan PP, Spiegel AM. Severe non-endocrine manifestations of the McCune-Albright syndrome associated with activating mutations of the stimulatory G protein Gs. J. Pediatr.  123:509-18, 1993.

8.  The DCCT Research Group, including Moran A.  The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus.  N. Engl. J. Med.  329:977-86, 1993.

9. Moran A, Pescovitz OH.  Long-term treatment of gigantism with combination octreotide and bromocriptine therapy in a child with McCune-Albright syndrome.  Endocrine Journal  2:111-3, 1994.

10. Moran A, Pyzdrowski K, Weinreb J, Kahn BB, Adams K, Seaquist ER.  Insulin sensitivity in cystic fibrosis.  Diabetes  43:1020-26, 1994.

11. Seaquist E, Pyzdrowski K, Moran A, Robertson RP.  Insulin-mediated and glucose-mediated glucose uptake are maintained following hemipancreatectomy.  Diabetologia, 37:1036-43, 1994.

12. Couce M, O'Brien TD, Moran A., Roche PC, Butler, PC.  Diabetes mellitus in cystic fibrosis is characterized by islet amyloidosis.  J. Clin Endocrinol. Metab. 81: 1267-72, 1996.

13. Milla C, Doherty L, Raatz S, Regelmann W, Schwarzenberg SJ, Moran A.  The glycemic response to dietary supplements in cystic fibrosis is dependent upon the carbohydrate content of the formula.  J Parenteral Enteral Nutr. 20: 182-6, 1996.

14.  Moran A, Zhang H-J, Olson KL, Poitout V, Robertson RP.  Differentiation of glucose toxicity from beta cell exhaustion in the pancreatic islet cell line, HIT-T15. J Clin Invest 99:534-9, 1997.

15.  Moran A, Doherty L, Wang X, Thomas W.  Abnormal glucose metabolism in cystic fibrosis.  J Pediatr. 133:10-17, 1998

16.  Dave-Sharma W, Wilson RC, Harbison MD, Newfield, R, Rassaghy-Azar M, Funder JW, Shackleton CHL, Bradlow HL, Wei J-Q, Hertecant J, Moran A, Neiberger RE, Balfe JW, Fattah A, Daneman D, Akkurt HI, Di Santis C, New MI.  Examination of genotype and phenotype relationships in 14 patients with apparent mineralocorticoid excess.  J Clin Endocrinol Metab. 83:2244-54. 1998

17.  Moran A, chair, and the consensus committee.  Guidelines for the diagnosis, screening and management of CF related diabetes.  Diabetes Research and Clinical Practice , 45: 55-71, 1999.

18.  Moran A, Steinberger J, Jacobs D, Hong C-P, Prineas R, Luepker R, Sinaiko AR. Insulin resistance during puberty: results from insulin clamp studies in 356 children.  Diabetes, 48: 2039-44. 1999

19.  Moran A.  Cystic fibrosis related diabetes.  Pediatric Diabetes.  1:41-48, 2000.

20.  Milla CE, Warwick WJ, Moran A.  Trends in pulmonary function in CF patients correlate with the results of oral glucose tolerance test at baseline. Am J Resp Crit Care Med.  In Press.

21.  Moran A , Milla C, Ducret R, Nair SK.  Protein metabolism in clinically stable adult CF patients with abnormal glucose tolerance.   Diabetes, 50:1336-43, 2001.

22.  Steinberger J, Moran A, Hong C-P, Jacobs DR, Sinaiko AR.  Adiposity in childhood predicts obesity and insulin resistance in young adulthood. J Pediatr, 138:469-73, 2001

23.  Sinaiko A, Jacobs DR, Steinberger J, Moran A, Luepker R, Rocchini AP, Prineas, RJ.  Insulin resistance syndrome in childhood. J Pediatr.

24.  Figueroa V, Milla C, Schwarzenberg SJ, Parks E, Moran, A. Abnormal lipid levels in cystic fibrosis.  In press, Am J Clin Nutr.

25.  Moran A, Phillips, J, Milla C.  Insulin and glucose excursion following pre-meal insulin lispro or repaglinide in cystic fibrosis related diabetes. Diabetes Care, in press, 2001.

26.  Keenan J, Pins J, Frazel C, Moran A, Turnquist L, HuangZ.  Oat (beta-glucan) fiber reduces systolic and diastolic blood pressure among moderate hypertensives: a pilot trial.  2001, J Family Practice, in press.

Invited Review Articles, Chapters, Editorials and Miscellaneous Publications

1.  Alford, JA, Beall R, Becker D, Clark L, Doershuk C, Dresing R, Holsclaw D, Kappy M, McPherson C, Moran A, Mueller D, Rosenbloom A, Rosenstein B, Selden R, Stallings V, Warwick W, Zipf W.  Consensus Conference on CF-related Diabetes Mellitus.  Cystic Fibrosis Foundation Consensus Conferences.  Vol I, Section IV, pg1-8, 1990.

2.  Moran A, Brown DM, Doherty L, Ainslie M, Sane K, Saxena K, Sheridan K, Spencer M, Sockalosky J, Ternand C.  Diagnosis, monitoring, and treatment of short stature in children: Twin Cities community standards. The Endocrinologist   5:272-7, 1995.

3.  Doherty L, Brown DM, Ainslie M, Eugster E, Hirsch B, Kashtan C, Moran A, Saxena K, Sheridan K, Sockalosky J, Spencer M, Summers CG, Ternand C.  Turner syndrome practice guidelines.  The Endocrinologist 7:443-447, 1997.

4.  Eugster E and Moran A.  Sexual determination, sexual differentiation and puberty.  In Endocrine Pathophysiology, Editor: Catherine B. Niewoehner, Publishers: Fence Creek Publishing, Madison, Connecticut. pg 237-55, 1998.

5.  Hardin DS and Moran A.  Diabetes Mellitus in Cystic Fibrosis. Endocrinology and Metabolism Clinics of North America  28:787-800, 1999.

6.  Riggs, AC, Seaquest, ER, Moran A.  Diagnosis and treatment of diabetes mellitus in patients with cystic fibrosis.  Current Opinion in Pulmonary Medicine.   5:378-82, 1999.

7.  Hardin D.S., Brunzell C., Schissel K., Schindler T., Moran A.  Managing cystic fibrosis related diabetes.  An instruction guide for patients and families.  Cystic Fibrosis Foundation 1999.

8.  Moran, A. When should hyperglycemia be treated in CF?--reply  (letter).  J Pediatr 136: 706-7. 2000.

9.  Moran A, Sinaiko A.  Influence of intrauterine environment on development of insulin resistance. Editorial.  J Pediatr 136:567-9, 2000.