John Wagner

Current Position:  Professor of Pediatrics University of Minnesota Medical School

Research Interests:

1. Umbilical Cord Blood Transplantation in Children and Adults. Ex vivo expansion of hematopoietic stem cells. Double unit transplantation. Non-myeloablative preparative therapies. Pre-implantation genetic diagnosis to select HLA identical embryo. Co-infusion of T-regulatory cells. Graft vs. leukemia effective therapies. 

2.  Fanconi Anemia. Novel preparative therapies. Gene therapy-multipotent adult stem cell. Phenotype-genotype correlations (collaboration with Rockefeller University).

• pathophysiology
• mechanism of hematopoietic cell somatic mosaicism in FANCA

3. Multipotent Adult Stem Cells (MAPC). Translational development/large scale manufacture of MAPC. Evaluation of MAPC therapeutic potential in congenital and acquired disorders. Genetic modification of MAPC

E-mail: wagne002@umn.edu

Curriculum Vitae