Kendall Wallace, Ph.D.
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Contact Information
| Phone: |
218-726-8899 |
| Fax: |
218-726-8014 |
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Email:
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kwallace@d.umn.edu |
Address:
256 SMed
1035 University Dr.
Duluth, MN 55812 |
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Professor of Biochemistry and Molecular Biology
Director, University of Minnesota Toxicology Graduate Program
Diplomate, American Board of Toxicology
Fellow, Academy of Toxicological Sciences
Research
Dr. Wallace conducts research focused primarily on the mechanisms by which foreign chemicals, including drugs and industrial and environmental pollutants, interfere with mitochondrial metabolism and genetics to bring about various metabolic diseases. His primary interest is the molecular mechanisms of pathogenesis. Agents that are being investigated include anticancer and anti-AIDS drugs, and perfluorinated chemicals. In collaboration with clinical oncologists and endocrinologists, some of this basic knowledge of the molecular regulation of mitochondrial biogenesis is being translated into developing novel strategies to enhance cancer chemotherapeutics and in the design of more effective antidiabetogenic treatment regimens.
Dr. Wallace is Past President of the Society of Toxicology, the American Board of Toxicology, and the Mitochondrial Research Society and Editor-in-Chief of the journal Toxicology. He is also Director of the University-wide Ph.D. graduate program in Toxicology where he oversees the curriculum and research programs of many students on both the Twin Cities and Duluth campuses as they progress towards completing their Ph.D. degrees.
EducationPh.D. Michigan State University, 1979
Post Doc, University of Iowa
Laboratory PersonnelJames Bjork, Assistant Scientist
Elisaveta Petkova, Senior Laboratory Technician
Josiah Ray, Graduate Student
Annette Rod, Junior Scientist
Andrew Skildum, Post-Doc
Mark Walters, Graduate Student
Publications and Professional ActivitiesPublications on PubMed
Patents
Cyclodextrin Compositions and Methods of Treating Viral Infections. March 21, 2002
SLWK Dkt No. 600.538PRV; UoM File No. Z0166
KB Wallace, MA Khan, RW Carlson, SA Rice, and MK Froberg.
Editorships
Editor: Toxicology
Associate Editor: Cardiovascular Toxicology
Books
Molecular Biology of the Toxic Response (eds., A. Puga and K.B. Wallace) Taylor & Francis (1998)
Free Radical Toxicology: Target Organ Toxicology Series (ed., K.B. Wallace), Taylor & Francis (1997)
Book Chapters
Starkov, A. and Wallace, K.B. (in press). “Yin and Yang of Mitochondrial ROS Generation” In: Oxidative Stess, Disease and Cancer (ed., K. Singh).
Wallace, K.B. “Doxorubicin-induced Mitochondrial Cardiomyopathy.” In: Mitochondria in Pathogenesis (eds., J.J. Lemasters and A.-L. Nieminen). Chapter 25, pp467-488. Kluwer Academic/Plenum Publishers, New York. (2001).
Wallace, K.B. "Free Radical-Mediated Chemical Cardiomyopathies." (Chapter 11) In: Free Radical Toxicology: The Target Organ Toxicology Series (ed., K.B. Wallace). Taylor and Francis (1997).
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