Contact Information Phone: 218-726-7280 Fax: 218-726-7937 Email: rziegler@d.umn.edu Address: 337 SMed 1035 University Drive Duluth, Mn 55812 http://www.med.umn.edu/duluth

Professor

Research

Education

Teaching

Publications

1. Ziegler, Richard J. and Alexander Tomasz.  “Binding of Competence Factor to Spheroplast Membrane Fraction of Pneumococci.”  Biochem.  Biophy. Res. Comm. 41: p.1342, 1970

2. Ziegler, Richard J. and L. Daneo-Moore.  “Effects of Essential Amino Acid Starvation in Streptococcus Faecalis-Structural Change in 50S Ribosomal Subunit.”  J. of Bact. 105: p.190, 1971.

3. Tomasz, Alexander, Eva Zanati and Richard Ziegler.  “DNA Uptake During Genetic Transformation and the Growing Zone of the Cell Envelope.”  Proc. Nat. Acad. Sc.-USA 68:  p. 1848, 1971.

4. Ziegler, Richard J. and R.S. Pozos.  “Ultrastructual Effects of Herpes Simplex Virus Type 2 Infection of Rat Dorsal Root Ganglia in Culture.”  J. of Neuropath. and Exp. Neurol. 36:  p.680, 1977.

5. Hartmann, Mary A. and Richard J. Ziegler.  “Protective Effects of Rat Splenic Lymphocytes and Peritoneal Exudate Cells on Herpes Simplex Virus Infection of Rat Dorsal Root Ganglia in Culture.” J. of Neuropath. and Exp. Neurol. 38: p. 165-176, 1979.

6. Ziegler, R. J. and R. E. Herman.  “In Vitro Peripheral Infection of Dorsal Root Ganglia in Culture by Herpes Simplex Virus.” Infect. and Immun. 28: p. 620, 1980.

7. Oakes, Steven G., Roger W. Petry, Richard J. Ziegler, and Robert S. Pozos.  “Electrophysiology Changes of HSV-1 Infected Dorsal Root Ganglia Neurons in Culture.”  J. Neuropath. Exp. Neurol. 40:380, 1981.

8. Ziegler, R.J. and R.S. Pozos.  “Effects of Lectins on Peripheral Infection by Herpes Simplex Virus of Rat Sensory Neurons in Culture.”  Infect. and Immun. 34:588, 1981.

9. Wigdahl, B.L., R.J. Ziegler, M. Sneve and F. Rapp.  “Herpes Simplex Virus Latency and Reactivation in Isolated Rat Sensory Neurons.”  Virol. 172:159-167, 1983.

10. Lycke, E. and R. Ziegler.  “Herpes Simplex Virus-Neuronal Cell Interactions.”  Adv. Biol. Psych. 12:97-111, 1983.

11. Wigdahl, B., A.C. Scheck, R.J. Ziegler, E. DeClercq, and F. Rapp. “Analysis of the Herpes Simplex Virus Genome During In Vitro Latency in Human Diploid Fibroblasts and Rat Sensory Neurons.”  J. Virol. 49:205-213, 1984.

12. Lycke, E., K. Kristensson, B. Svennerholm, A. Vahlne, and R. Ziegler.  “Uptake and Transport of Herpes Simplex Virus in Neurites of Rat Dorsal Ganglia Cells in Culture.”  J. Gen. Virol. 65:55-64, 1984.

13. Svennerholm, B., R. Ziegler, and E. Lycke.  “Neuritic Uptake and Transport of Antiviral Drugs Modifying Herpes Simplex Virus of Rat Sensory Neurons.”  Arch. Virol. 81:213-222, 1984.

14. Ziegler, R. and R.S. Pozos.  “Inability of Various Immune Mechanisms to Establish In Vitro Latent Infection in Sensory Neurons Infected by HSV-1.”  Arch. Virol. 79:123-130, 1984.

15. Ljungdahl, A., Kristensson, K., Lundberg, J.M., Lycke, E., Svennerholm, B., Ziegler, R.  “Herpes Simplex Virus Infection in Capsaicin-Treated Mice.”  J. Neurol. Sci. 72:223-230, 1986.

16. Ziegler, R.J. and E.K. Stauffer, “Mumps-Induced Alterations in Cellular Excitability During Persistent Infections.”  J. Gen. Virol. 68:2501-2507, 1987.

17. Lycke, E., B. Svennerholm, A. Vahlne, and R. Ziegler.  “The Herpes Simplex Virus Infection fo the Rat Sensory Neurons.” In:  Viruses, Immunity, and Mental Disorders.  Ed. Kurstak, Lipowski, and Morozov, Plenum Press, pp. 221-226, 1987.

18. Ziegler, R.J.  “In Vitro Cultivation of Nerve Cells as Model for Studies on Nerve Cell-Virus Interactions.” In:  Viruses, Immunity, and Mental Disorders.  Ed. Kurstak, Lipowski, and Morozov. Plenum Press, pp. 227-234. 1987.

19. Kaufmann, C.A. and R.J. Ziegler.  “The Viral Hypothesis of Schizophrenia.”  In:  Receptors and Ligands in Psychiatry. Ed. Y. Sen and T. Lee.  Cambridge Univ. Press. pp. 187 -208, 1988.

20. Drewett, J., Marchand, G., Ziegler, R., and G. Trachte. “Atrial Natriuretic Factor Inhibits Norepinephrine Release in an Adrenergic Neuron Cell-Line (PC 12).”  Eur. J. of Pharm. 150:175-179, 1988.

21. Trachte, G.J., Hook P.H., Kemp J.R., Acosta E.P., and R.J. Ziegler “Thromboxane and Prostaglandin Production by Isolated Adrenergic Nerve (PC-12) cells.  J. Pharmacol. Exp. Therapeutics 247:43-46, 1988.

22. Drewett, J.G., Ziegler, R.J., Marchand, G.R., and J.G. Trachte. “Cyclic Guanosine 3’. 5’ Monophosphate Mediates the Inhibitory Effect of Atrial Natriuretic Factor in Adnergenic, Neuronal Pheochromocytoma Cells.” J. Pharmacol. Exp. Therapeutics 250:428-432, 1988.

23. Stauffer, E.K. and R.J. Ziegler.  “Loss of Functional Voltage-Gated Sodium Channels in Persistent Mumps Virus-Infected PC-12 Cells.  J. Gen. Virol. 70:749 -754, 1989.

24. Svennerholm, B., Ziegler, R.J., and E. Lycke.  “HSV Infection of Rat Sensory Neurons.  Effects of Interferon on Cultured Cells.” Arch. Virol. 104:153-156, 1989.

25. Drewett, J.G., R.J.Ziegler, and G.J. Trachte.  “Neuromodulatory Effects of ANF are Independent of Guanylate Cyclase in Adrenergic Neuronal Pheochromocytoma Cells.”  J. Pharm. Exp. Therapeutics 255: 497-503, 1990.

26. Drewett, J.G., R.J. Ziegler, and G.J. Trachte.  “Neuromodulatory effects of atrial natriuretic peptides correlate with an inhibition of adenylate cyclase but not an activation of guanylate cyclase.  J. Pharmacol. Exp. Ther. 260:689-696, 1992. press, J. Pharm. Exp. Therapeutics, July 1992.

27. Trachte, G.J., S. Kanwal, B.J. Elmquist and R.J. Ziegler.  "C-type Natriuretic Peptide Neuromodulates via 'Clearance' Receptors."   Amer. J. Physiol., 268:C978-C984, 1995.

28. Ziegler, R. J.  "HIV-1 gp120 Effects on Signal Transduction Processes and Cytokines:  Increased src-Family Protein Tyrosine Kinase Activity."  Journal of Neuro-AIDS, 1:51-71, 1996.
    

Published books:

1. Johnson, A.G., Ziegler, R., Lukasewycz, O., and L. Hawley.  Board Review Series “Microbiology and Immunology,” 4^th edition, Williams & Wilkins, 2002.