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Education & Training
Dr. McSorley received his Ph.D. from the University of Glasgow, Scotland, and completed post-doctoral fellowships at both the University of Nice, France, and the University of Minnesota.
He became a faculty member in the Department of Medicine at the University of Connecticut Health Center in 2001, and moved to the University of Minnesota in 2005 as an Assistant Professor in the GI Division. He is a faculty member in the Microbiology, Immunology, and Cancer Biology (MiCaB) program, a member of the Center for Immunology, and a member of the Center for Infectious Diseases and Microbiology Translational Research. His research is focused on the activation of T cell responses in the gut mucosa during infectious and inflammatory bowel disease.
Research
Intestinal Immune Responses to Bacteria
Salmonella typhi causes typhoid fever, a common gastrointestinal infection in many developing nations. Currently typhoid vaccines are only moderately effective or unsafe for use by the very young or elderly. Research in our laboratory focuses on understanding the activation of innate and adaptive immune responses to Salmonella with a view to development of novel typhoid vaccines. Our laboratory is also actively developing a novel model of antigen-specific colitis and attempting to identify how and where T cells responsive to normal enteric flora are activated in vivo.
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Contact Information
Phone:
612-625-8999
Fax:
612-625-5620
Email:
mcsor002@umn.edu
Address:
Dept. of Medicine
GI Division, MMC 36
420 Delaware St., S.E.
Minnapolis, MN 55455
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