Dr. Craig Eckfeldt graduated from the University of Minnesota’s Combined M.D./Ph.D. Program with a Ph.D. in Microbiology, Immunology and Cancer Biology (advisor: Catherine Verfaillie, M.D.) in 2005 and an M.D. in Internal Medicine in 2007.He received the Minnesota Medical Foundation J. Thomas Livermore Award in 2005 and was elected to Alpha Omega Alpha Honor Society in 2006.Dr. Eckfeldt entered the fellowship program in Hematology, Oncology and Transplantation at the University of Minnesota in 2009.
Publications
Bertrand FE, Eckfeldt CE, Fink JR, Lysholm AS, Pribyl JA, Shah N, LeBien TW.Microenvironmental influences on human B-cell development.Immunol Rev 2000; 175:175-186.
Bertrand FE, Eckfeldt CE, Lysholm AS, LeBien TW.Notch-1 and Notch-2 exhibit unique patterns of expression in human B-lineage cells.Leukemia 2000; 14:2095-2102.
Hematti P, Hong BK, Ferguson C, Adler R, Hanawa H, Sellers S, Holt IE, Eckfeldt CE, Sharma Y, Schmidt M, von Kalle C, Persons DA, Billings EM, Verfaillie CM, Nienhuis AW, Wolfsberg TG, Dunbar CE, Calmels B.Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells.PLoS Biol 2004; 2:e423.
Leung AY, Mendenhall EM, Kwan TT, Liang R, Eckfeldt C, Chen E, Hammerschmidt M, Grindley S, Ekker SC, Verfaillie CM.Characterization of expanded intermediate cell mass in zebrafish chordin morphant embryos.Dev Biol 2005; 277:235-254.
Eckfeldt CE, Mendenhall EM, Flynn CM, Want T, Pickart MA, Grindle SM, Ekker SC, Verfaillie CM.Functional analysis of hematopoietic stem cell gene expression using zebrafish.PLoS Biol 2005; 3:e254.
Eckfeldt CE, Mendenhall EM, Verfaillie CM.The molecular repertoire of the “almighty“ stem cell.Nat Rev Mol Cell Biol 2006; 6:726-737.
Pickart MA, Klee EW, Nielsen AL, Sivasubbu S, Mendenhall EM, Bill BR, Chen E, Eckfeldt CE, Knowlton M, Robu ME, Larson JD, Deng Y, Schimmenti LA, Ellis LBM, Verfaillie CM, Hammerschmidt M, Farber SA, Ekker SC.Genome-wide reverse genetics framework to identify novel functions of the vertebrate secretome.PLoS ONE 2006; 1:e104.
Patterson LJ, Gering M, Eckfeldt CE, Green AR, Verfaillie CM, Ekker SC, Patient R.The transcription factors, Sci and Lmo2 act together during the development of the haemangioblast in zebrafish.Blood 2007; 109:2389-2398.
Presentations
Leung AYH, Eckfeldt CE, Liu E, Verfaillie CM.Differential gene expression of primitive hematopoietic stem/progenitor cells derived from human umbilical cord blood.American Society of Hematology meeting; Philadelphia, PA; December 2002.
Mendenhall EM, Eckfeldt CE, Pickart MA, Ekker SC, Verfaillie CM.Analysis of gene expression data from human hematopoietic stem cells in zebrafish.Sixth Annual International Conference on Zebrafish Development and Genetics; Madison, WI; July 2004.
Eckfeldt CE, Mendenhall EM, Flynn CM, Wang T-F, Ekker SC, Verfaillie CM.Functional analysis of the differential gene expression profile of human HSC using a functional genomics screen in the zebrafish.American Society for Clinical Investigation/Association of American Physicians Joint Meeting; Chicago, IL; April 2005.
Eckfeldt CE, Mendenhall, Verfaillie CM.SPRY1 is a negative regulator of long-term in vivo engraftment and ex vivo expansion of primitive human umbilical cord blood cells.American Society of Hematology Annual Meeting; Atlanta, GA; December 2005.
