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Sheng, Wen


 Dr. Sheng Wen S. Sheng, Ph.D. is a senior research associate in the Department of Medicine and a research scientist in the Neuroimmunology Laboratory at Minneapolis Medical Research Foundation. She received her doctoral degree from the Virginia Polytechnic Institute and State University. She is involved in studies of gene expression of primary brain cell cultures exposed to drugs, cytokines/chemokines and human viruses/viral proteins.

Selected Publications:

Sheng WS, Hu S, Lokensgard JR, Peterson PK. U50,488 inhibits HIV-1 Tat-induced monocyte chemoattractant protein-1 (CCL2) production by human astrocytes. Biochem Pharmacol. 2003; 65(1):9-14.

Hu S, Sheng WS, Lokensgard JR, Peterson PK. Morphine induces apoptosis of human microglia and neurons. Neuropharmacology 2002; 42(6):829-36.

Lokensgard JR, Hu S, Sheng WS, vanOijen M, Cox D, Cheeran MC, Peterson PK. Robust expression of TNF-alpha, IL-1beta, RANTES, and IP-10 by human microglial cells during nonproductive infection with herpes simplex virus. J Neurovirol 2001;7:208-219.

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