Training Grant
UNIVERSITY OF MINNESOTA INFECTIOUS DISEASES FELLOWSHIP TRAINING IN CLINICAL EPIDEMIOLOGY AND CLINICAL TRIALS RESEARCH
Description: Because of the increased need for Infectious Diseases Clinical Investigators to address the growing crisis of emerging and re-emerging infections, the Departments of Internal Medicine and Pediatrics at the University of Minnesota Medical School offer a training track for fellows interested in acquiring skills in the areas of clinical epidemiology and clinical trials research.
This multidisciplinary, NIH-supported T32 Training Program "Infectious Disease Training In Clinical Research" draws upon a large number of University of Minnesota faculty members and colleagues at the Minnesota Department of Health.
Fellows entering this two year-training track will generally be second year fellows who have completed a clinical year of adult or pediatric Infectious Diseases training.
In addition to working closely with a primary mentor on a research project related to an Emerging Infectious Disease topic (see list of training areas and primary mentors below), fellows will have an opportunity to take relevant courses in the School of Public Health. When desirable, this course work can lead to a Master of Public Health (MPH) degree (for fellows interested primarily in epidemiology-focused research) or a Master of Science (MS) in Clinical Research degree (for fellows interested in clinical trials or other clinically based research).
Selection of a Primary Mentor is encouraged early in the first year of clinical training. In addition to receiving major guidance from their primary mentors regarding selection and refinement of their research projects, fellows will have the benefit of periodic input from other faculty preceptors on the organization of their projects.
Training Areas and Faculty
1. HIV/AIDS
Primary Mentors: Paul Bohjanen, Ashley Haase,
James Neaton, Timothy Schacker
Other Preceptors: Peter Carr, Winston Cavert, Keith Henry,
Alan Lifson, Frank Rhame
2. Invasive Bacterial Infections
Primary Mentors: Sandra Armstrong, Patricia Ferrieri,
Richard Isaacson, Ruth Lynfield, Stephen McSorely,
Marnie Peterson,
Other Preceptors: Patrick Cleary, Kent Crossley, Gary Dunny,
Kristen Ehresmann, Patrick Schlievert
3. Antibiotic Resistance
Primary Mentors: Gunda Georg, James Johnson, Ruth Lynfield
Other Preceptors: Kent Crossley, Gregory Filice,
Dean Tsukayama, David Williams
4. Immunodeficiency/Vaccines
Primary Mentors: Judith Berman, Paul Bohjanen, Ashley Haase,
Kristen Hogquist, Kristin Nichol, Kirsten Nielsen, Phillip Peterson,
Timothy Schacker, Leslie Schiff, Mark Schleiss
Other Preceptors: Richard Danila, Susan Kline, Ruth Lynfield,
Vicki Morrison, Jo-Anne (van Burik) Young
5. International and Immigrant Health
Primary Mentors: Paul Bohjanen, Chandy John, Michael Osterholm, Phillip Peterson, William Stauffer
Other Preceptors: Cynthia Howard, Alan Lifson, Ramaiah Muthyala,
Patricia Walker, David Williams
6. Bioterrorism
Primary Mentors: Michael Osterholm, Timothy Schacker
Other Preceptors: Richard Danila, Ruth Lynfield, Dean Tsukayama
7. Foodborne Infections
Primary Mentors: James Johnson, Ruth Lynfield, Stephen McSorley, Michael Osterholm
Other Preceptors: Jeff Bender, Craig Hedberg, Will Hueston,
Kirk Smith
8. Zoonoses
Primary Mentors: Marie Gramer, Richard Isaacson, Ruth Lynfield,
Tom Molitor, Claudia Munoz-Zanzi
Other Preceptors: Jeffrey Bender, James Johnson, David Neitzel,
Joni Scheftel
Primary Mentors Area of Research Interests:
| Faculty Name/Degree |
Primary
(Secondary) Appointment(s) |
Areas of Research Interest |
Armstrong, Sandra, PhD
Associate Professor |
Microbiology |
Pathogenesis of
Bordetella pertussis |
Berman, Judith, PhD
Professor |
Genetics (Cell Biology & Development, Microbiology) |
Biology of Candida albicans, including genomes stability, acquisition of drug resistance, morphogenesis and basic aspects of centromere function and DNA replication regulation |
Bohjanen, Paul, MD, PhD
Associate Professor |
Microbiology
(Medicine) |
T Lymphocyte mRNA stability; inflammatory and immune dysregulation in HIV infection |
Ferrieri, Patricia, MD
Professor |
Pediatrics |
Trials of vaccines for otitis
media; epidemiology of
perinatal infection |
Georg, Gunda, PhD
Professor |
Medicinal Chemistry
Pharmacy |
Synthetic medicinal chemistry, structure-activity relationship studies, structure-based drug design, natural products chemistry, total synthesis, high throughput screening |
Gramer, Marie, DVM, PhD
Assistant Clinical Professor |
Veterinary
Population Medicine |
Diseases of food animals, especially swine; antigenic and genetic characterization of swine influenza viruses (SIV), pathogenesis of unique SIV infections in pigs, and the possible impact these viruses may have on current vaccination protocols in place in the US
swine industry |
Haase, Ashley, MD
Regents Professor and Chair (Adjunct Professor) |
Microbiology
(Medicine) |
Animal and human lentiviruses and HIV, including immunopathogenesis and lymphatic tissue effects |
Hogquist, Kristin, PhD
Professor |
Laboratory
Medicine & Pathology
(Center for
Immunology) |
Innate and adaptive immune response to Epstein Barr Virus |
Isaacson, Richard, PhD
Professor |
Microbiology (Veterinary
Biosciences) |
Virulence mechanisms of E. coli that cause nosocomial
septicemia; microbiome of pigs that are subjected to growth promoting antibiotics; the mechanism
whereby S. typhimurium can
persistently infect pigs, yet not cause disease |
John, Chandy, MD, MS
Associate Professor |
Pediatrics
(Medicine) |
Cerebral cytokine response to malaria and risk of
neurocognitive sequelae in African children |
Johnson, James, MD
Professor |
Medicine
(School of Public
Health, Graduate
School) |
Clinical and laboratory aspect of E.coli and Enterococcus infections, including diagnosis, management, pathogenesis, molecular epidemiology,
reservoirs, transmission, evolution, and antimicrobial resistance |
Lynfield, Ruth, MD
Adjunct Associate Professor (State Epidemiologist) |
Medicine
(Minnesota
Department of
Health) |
Emerging infectious diseases, antibiotic resistance, unexplained infectious deaths and smallpox |
McSorley, Stephen, PhD
Associate Professor |
Medicine |
Immunity to bacterial infection, especially in salmonellosis |
|
Molitor, Thomas, PhD
Professor
|
Veterinary Population Medicine |
|
Munoz-Zanzi, Claudia DVM, MPVM, PhD
Assistant Professor |
Epidemiology |
Diagnosis and epidemiology of zoonotic infectious diseases, in particular leptospirosis and toxoplasmosis, including evaluation and application of diagnostic assays, screening, mechanisms of population-level transmission, ecology, primary intervention programs, and public health impact |
Neaton, James, PhD
Professor
(Adjunct Professor) |
Biostatistics
(Medicine) |
HIV infection: natural history and anti-retroviral therapy; biostatistical coordinating center for large multi-center trials and cohort studies |
Nichol, Kristin, MD
Professor |
Medicine |
Clinical research method (Clinical epidemiology, clinical trials, health economics); Preventive medicine & adult vaccine preventable diseases |
Nielson, Kirsten, PhD
Assistant Professor |
Microbiology |
Pathogenesis of fungal infections, especially Cryptococcus, including virulence factors, growth in lungs, penetration of the blood-brain barrier, antibiotic resistance, environmental reservoirs, and molecular epidemiology |
Osterholm, Michael, PhD, MPH
Professor
(Adjunct Professor) |
Public Health (Medicine) |
Epidemiology of infectious
diseases, bioterrorism,
foodborne diseases; influenza research and surveillance |
Peterson, Marnie, PharmD, PhD
Assistant Professor |
Experimental &
Clinical Pharmacology
(Microbiology) |
Pathogenesis of staphylococcal infections, especially bacterial-epithelial cell interactions |
Peterson, Phillip, MD
Professor |
Medicine
(Graduate Faculty,
Veterinary Medicine) |
Novel pharmacologic intervention for and immunopathogenesis of CNS |
Schacker, Timothy, MD
Professor |
Medicine |
Factors that increase the
likelihood and efficiency of HIV transmission and T cell
homeostasis in HIV-1 infected persons |
Schleiss, Mark, MD
Professor |
Pediatrics |
Newborn screening for CMV; molecular epidemiology of CMV infection; hearing loss in newborns |
Stauffer, William, MD MSPH, DTMH,
Associate Professor |
Medicine (School of Public Health) |
Infectious diseases pathophysiology, epidemiology, surveillance and policy development/evaluation in mobile populations; travel medicine, special populations; emerging infections (zoonosis) in developing countries |
Other Preceptors:
| Faculty Name/Degree |
Primary (Secondary) Appointment(s) |
Areas of Research Interest |
Bender, Jeff DVM, MS
Associate Professor |
Veterinary Medicine (School of Public Health) |
Antimicrobial resistance, food safety, infectious disease surveillance and epidemiology of zoonotic diseases |
Carr, Peter, MPH
STD/AIDS
Director |
Minnesota Department of Health |
STD and HIV epidemiology, HIV drug
resistance and subtype surveillance,
sexual health behavioral surveillance |
Cleary, Patrick, PhD
Professor |
Microbiology |
Molecular pathogenesis and prevention of group A streptococcal infections, particularly with respect to the C5a surface protease, host cell signaling, extracellular matrix proteins , TGF-β1 in host suseptibility, streptococcal persistence in tonsils, and T cell immunity; an intranasal mouse infection model is used to investigate host immunity |
Danila, Richard, PhD, MPH,
Adjunct Assistant Professor (Assistant State Epidemiologist) |
Epidemiology (Minnesota Department of Health) |
Epidemiology of emerging and novel bacterial and viral pathogens; outbreaks of unknown etiology; translation of research findings into public health practice |
Filice, Gregory, MD
Professor
(Chief of Infectious Disease Section) |
Medicine
(VAMC) |
Antimicrobial therapy, specifically stratagies to optimize prescribing to improve outcomes and prevent resistance; decision support; informatics; clionical research on infectious disease and related topics |
Henry, Keith, MD,
Professor of Medicine |
Medicine (School of Public Health) |
HIV infection-antiretroviral therapy (novel regimens and strategies, complications), aging with HIV, prevention, long-term outcomes |
Lifson, Alan, MD, MPH
Professor |
Epidemiology (School of Public Health) |
HIV/AIDS (including clinical epidemiology) and international health |
Morrison, Vicki, MD
Associate Professor |
Medicine |
Infectious complications of hematology/oncology patients; transplant related lymphoproliferative disorders; complications in chronic lymphocytic leukemia; Varicella zoster infections |
Muthyala, Ramaiah, PhD
Associate Professor |
Pharmacy |
Discovery and drug development for antibiotic resistant pathogens |
Neitzel, David, MS
Epidemiologist |
Minnesota Department of Health |
Vector-borne diseases: Special interest in the local epidemiology of tick-borne (e.g., Lyme disease, human anaplasmosis, etc.) and mosquito-borne (e.g., West Nile virus, La Crosse encephalitis) diseases. |
Scheftel, Joni, DVM, MPH
Adjunct Professor |
Veterinary Medicine, Veterinary Population Medicine |
Zoonotic disease surveillance, prevention and control, veterinary infection control, ecosystem health and policy at the intersection of animal agriculture and human health |
Schlievert, Patrick, PhD
Professor |
Microbiology |
Interaction of Staphylococcus aureus, group A streptococci, and Enterococcus faecalis with the host immune system; mechanisms of pathogenesis; development of novel strategies to prevent and manage infections; immune system responses |
Walker, Patricia, MD
Associate Professor |
Medicine |
International clinical care and medical education and interventions designed to reduce health disparities amongst refugees, immigrants and travelers |
|
