Betsy Hirsch, Ph.D.

Professor
Lab Medicine and Pathology
Ph: (612) 273-4952
Fax: (612) 273-4689
email: hirsc003@umn.edu

Research Interests

Dr. Hirsch uses cytogenetic techniques to elucidate constitutional and acquired chromosome abnormalities. In clinically oriented studies, her laboratory is involved in the development and application of high resolution chromosome banding and fluorescence in situ hybridization techniques. In more basic studies, research in Dr. Hirsch's laboratory is focused upon the identification of genetic and environmental factors that can predict an individual's cellular responses to the induction of DNA damage and can account for the observed inter-individual variability in these responses.

Recent Publications

• John J. Gregory Jr., John E. Wagner, Peter C. Verlander, Orna Levran, Sat Dev Batish, Cindy R. Eide, Amy Steffenhagen, Betsy Hirsch, and Arleen D. Auerbach. Somatic mosaicism in Fanconi anemia: Evidence of genotypic reversion in lymphohematopoietic stem cells PNAS 2001 98: 2532-2537 American Journal of Medical Genetics 45:5-8, 1993.
• Raymond CS, Shamu CE, Shen MM, Seifert KJ, Hirsch B, Jodgkin J, Zarkower D, Evidence for evolutionary conservation of sex-determining genes. Nature, 391(6668): 691-695, 1998
• Eugster EA, Berry SA, Hirsch B, Mosaicism for deletion 1p36.33 in a patient with obesity and hyperphagia. American Jounral of Medical Genetics. 70(4):409-412, 1997