Daniel J. Garry, MD, PhD

Professor of Medicine
St. Jude Medical Endowed Chair in Cardiology
Director, Lillehei Heart Institute
Chief, Cardiovascular Division, Department of Medicine

Practice Philosophy

"My philosophy is to provide outstanding comprehensive care to patients with cardiovascular disease, including a number of emerging technologies available at the University of Minnesota Medical Center-Fairview. My practice combines state-of-the-art therapies, compassion, and effective communication, creating a working partnership that results (overall) in high quality of life for my patients."

Specialties

Clinical: Heart failure and cardiac transplantation
Research: Regenerative medicine, cardiogenesis, and stem-cell biology

Medical School

M.D., Medicine, University of MN Hospitals and Clinics, Minneapolis, MN

Residency

Department of Medicine, University of MN Hospitals, Minneapolis, MN

Fellowship

UT Southwestern Medical Center, Dallas, TX
Postdoctoral Fellow, Molecular Cardiology, UT Southwestern Medical Center at Dallas, Dallas, TX

Professional Associations

2007-present Association of Professors of Cardiology
2007-present Developmental Biology Society
2006-present Fellow, American Heart Association
1998-present American Heart Association (Basic Science Council)
1993-present American Medical Association
1990-present American Association for the Advancement of Science

Recent Publications

2009

Singh S, Manda SM, Sikder D, Birrer MJ, Rothermel BA, Garry DJ, Mammen PP. Calcineurin activates cytoglobin transcription in hypoxic myocytes. J Biol Chem 2009;284:10409-10421.

Kanatous SB, Mammen PP, Rosenberg PB, Martin CM, White MD, Dimaio JM, Huang G, Muallem S, Garry DJ. Hypoxia reprograms calcium signaling and regulates myoglobin expression. Am J Physiol Cell Physiol 2009;296:C393-C402.

Ferdous A, Caprioli A, Iacovino M, Martin CM, Morris J, Richardson JA, Latif S, Hammer RE, Harvey RP, Olson EN, Kyba M, Garry DJ. Nkx2-5 transactivates the Ets-related protein 71 gene and specifies an endothelial/endocardial fate in the developing embryo. Proc Natl Acad Sci USA 2009;106:814-819.

2008

Sadek H, Latif S, Collins R, Garry MG, Garry DJ. Use of ferumoxides for stem-cell labeling. Regen Med 2008;3:807-816.

Martin CM, Ferdous A, Gallardo T, Humphries C, Sadek H, Caprioli A, Garcia JA, Szweda LI, Garry MG, Garry DJ. Hypoxia-inducible factor-2alpha transactivates Abcg2 and promotes cytoprotection in cardiac side-population cells. Circ Res 2008;102:1075-1081.

Sadek H, Hannack B, Choe E, Wang J, Latif S, Garry MG, Garry DJ, Longgood J, Frantz DE, Olson EN, Hsieh J, Schneider JW. Cardiogenic small molecules that enhance myocardial repair by stem cells. Proc Natl Acad Sci USA 2008;105:6063-6068.

Weaver CV, Garry DJ. Regenerative biology: A historical perspective and modern applications. Regen Med 2008;3:63-82.

2007

Hawke TJ, Atkinson DJ, Kanatous SB, Van der Ven PF, Goetsch SC, Garry DJ. Xin, an actin binding protein, is expressed within muscle satellite cells and newly regenerated skeletal-muscle fibers. Am J Physiol Cell Physiol 2007;293:C1636-C1644.

Naseem RH, Meeson AP, Michael Dimaio J, White MD, Kallhoff J, Humphries C, Goetsch SC, De Windt LJ, Williams MA, Garry MG, Garry DJ. Reparative myocardial mechanisms in adult C57BL/6 and MRL mice following injury. Physiol Genomics 2007;30:44-52.

Meeson AP, Shi X, Alexander MS, Williams RS, Allen RE, Jiang N, Adham IM, Goetsch SC, Hammer RE, Garry DJ. Sox15 and Fhl3 transcriptionally coactivate Foxk1 and regulate myogenic progenitor cells. EMBO J 2007;26:1902-1912.

Garry DJ, Mammen PP. Molecular insights into the functional role of myoglobin. Adv Exp Med Biol 2007;618:181-193.

2006

Garry DJ, Olson EN. A common progenitor at the heart of development. Cell 2006;127:1101-1104.

Mammen PP, Shelton JM, Ye Q, Kanatous SB, McGrath AJ, Richardson JA, Garry DJ. Cytoglobin is a stress-responsive hemoprotein expressed in the developing and adult brain. J Histochem Cytochem 2006;54:1349-1361.

Latif S, Masino A, Garry DJ. Transcriptional pathways direct cardiac development and regeneration. Trends Cardiovasc Med 2006;16:234-240.

Shi X, Garry DJ. Muscle stem cells in development, regeneration, and disease.  Genes Dev 2006;20:1692-1708.

Lee Y, Naseem RH, Park BH, Garry DJ, Richardson JA, Schaffer JE, Unger RH.
Alpha-lipoic acid prevents lipotoxic cardiomyopathy in acyl CoA-synthase transgenic mice. Biochem Biophys Res Commun 2006;344:446-452.

Kanatous SB, Garry DJ. Gene-deletional strategies reveal novel physiological
roles for myoglobin in striated muscle. Respir Physiol Neurobiol 2006;151:151-158.

Hawke TJ, Kanatous SB, Martin CM, Goetsch SC, Garry DJ. Rad is temporally regulated within myogenic progenitor cells during skeletal muscle regeneration.
Am J Physiol Cell Physiol 2006;290:C379-C387.

Martin CM, Russell JL, Ferdous A, Garry DJ. Molecular signatures define myogenic stem-cell populations. Stem Cell Rev 2006;2:37-42.