Marcos T. Kuroki

Year Entered: 2006

Honors and Awards:
Provost Undergraduate Research Award (Johns Hopkins University), Summer 2005
Tau Beta Pi (Maryland Alpha Chapter), 2004

Degrees Received:
B.S., Biomedical Engineering, Johns Hopkins, 2005

Thesis Advisor: John Osborne, Ph.D., Neuroscience Graduate Program

Thesis Research: The role of the CNS in the pathogenesis of hypertension

Marcos is interested in understanding the role of the central nervous system in the long term regulation of arterial blood pressure and developing a framework for understanding the pathogenesis of primary hypertension. Using chronically instrumented rats, MRI, and mathematical modeling, he will be studying the synergistic effect of salt and deoxycorticosterone acetate (DOCA) on the hypothalamus as the driving force for the long term maintenance of hypertension. The Osborn group is part of an NIH-funded multi-institutional consortium, "The Neurogenic Cardiovascular Diseases Consortium," and has been advancing the field through molecular and animal studies. The Osborn lab focuses primarily on the pathogenesis of hypertension using the DOCA-salt rat model, and employs long-term telemetric hemodynamic and neural recordings for studying the different phases during the development of hypertension.

Publications: (prior to entering MD/PhD Program)

Zhang, CY,  Yeh, HC, Kuroki MT, Wang TH. Single-quantum-dot-based DNA nanosensor. Nature Materials, 2005;4:826 –831.

Poster/Abstract: (prior to entering MD/PhD Program) 

Kuroki MT, Hardick J, Gaydos C, Rothman R, Yang S. Rapid Polymerase Chain Reaction-based Screening Algorithm for Bacterial Biothreat Agents. Acad Emerg Med, 2006; 13: S119-a.