Michael A. Weinreich

Year Entered: 2004

Degrees Received:
B.S., Biology, University of Washington , 2001

Honors and Awards:
J. Thomas Livermore Award for outstanding research in hematology, Minnesota Medical Foundation, 2007

Thesis Advisor: Kris Hogquist, Ph.D., MICaB Graduate Program

Thesis Research:

Our lab has identified Kruppel Like Factor 2 (KLF2) as a transcription factor necessary for T cell trafficking out of the thymus and into secondary lymphoid tissue.  I am working on the cellular signaling that controls KLF2 expression in the thymus. 

Publications:

Weinreich MA, Hogquist KA. Thymic emigration: when and how T cells leave home. J Immunol. 2008;181:2265-2270.

Hogquist KA, Weinreich MA, Jameson SC. Kruppeled T cells move again. Immunol Cell Biol. 2008;86:297-298.

Carlson CM, Endrizzi BT, Wu J, Ding X, Weinreich MA, Walsh ER, Wani M.A., Lingrel J.B., Hogquist K.A., Jameson S.C. Lung Kruppel-like factor regulates thymocyte and T cell migration. Nature 2006;442:299-302.

Publications Prior to Entering MD/PhD Program:

Weinreich MA, Lintmaer I, Wang L, Liggitt HD, Harkey MA, Blau CA. Growth factor receptors as regulators of hematopoiesis.Blood 2006;108:3713-1321.

Zhao S, Weinreich MA, Ihara K, Richard RE, Blau CA. In vivo selection of genetically modified erythroid cells using a Jak2-based cell growth switch. Mol Ther. 2004;10:456-468.

Richard RE, Weinreich M, Chang KH, Ieremia J, Stevenson M, Blau C. A. Modulating erythrocyte mixed Cchimerism in a mouse model of pyruvate kinase deficiency. Blood. 2004;103:4432-4439.

Ali M, Weinreich M, Balcaitis S, Cooper CJ, Fink PJ. Differential regulation of tolerance induced by deletion and TCR revision in VBeta5 transgenic mice. J Immunol. 2003; 171:6290-6296.