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Clinical Trials


GYNECOLOGY (uterine, ovary, cervix)
PROTOCOL DETAILS
PROTOCOL TITLE DISEASE SITE

Principal Investigator:
Peter Argenta
Contact:
Sharon Donnelly or
Marva Bohen
info@cancer.umn.edu
(612) 624-2620
A randomized, parallel group, open-label, active controlled, multicenter Phase III trial of Patupilone (EPO906) versus pegylated liposomal doxrorubicin (Doxil/Caelyx) in taxane/platinum refractory/resistant patients with recurrent epithelial ovarian, primary fallopian or primary peritoneal cancer (Study No. CEPO906A2303) Ovarian, Fallopian, Primary Peritoneal

Principal Investigator:
Peter Argenta
Contact:
Deborah Biegert
biege001@umn.edu
612-624-8647

WCC #49 Phase II Trial of Fulvestrant in Treatment of Recurrent Ovarian Carcinoma Ovarian

Principal Investigator:
Linda Carson
Contact:
Suann Mitchell
mitch016@umn.edu
612-624-1919

GOG 0212: A Randomized Phase Trial of Maintenance Chemotherapy Comparing 12 Monthly Cycles of Single Agent Paclitaxel or Xyotax (CT-2103) Versus No Treatment Until Documented Relapse in Women with Response to Primary Platinum/Taxane Chemotherapy  

Principal Investigator:
Linda Carson
Contact:
Suann Mitchell
mitch016@umn.edu
612-624-1919

WCC 34 A Phase I Study of Adjuvant Topotecan and Cisplatin with Concurrent Radiation Therapy for Advanced Cervical Cancer Cervical, Uterine

Principal Investigator:
Levi Downs
Contact:
Sharon Donnelly or
Marva Bohen
info@cancer.umn.edu
(612) 624-2620
WCC #45: Prolonged Venous Thromboembolism Prophylaxis with Fondaparinux in Gynecologic Oncology Patients: An Open Label Phase II Trial  

Principal Investigator:
Levi Downs
Contact:
Sharon Donnelly or
Marva Bohen
info@cancer.umn.edu
(612) 624-2620
A Multi-Center, Double-Blinded, Randomized, Placebo-Controlled Study of ZYC101a in the Treatment of High-Grade Cervical Intraepithelial Lesions (CIN2/3) of the Uterine Cervix Uterine, Cervical

Principal Investigator:
Levi Downs
Contact:
Sharon Donnelly or
Marva Bohen
info@cancer.umn.edu
(612) 624-2620
WCC# 44: A Pilot Study of CerviPrep, a Novel Drug Delivery Device for the Cervix, in the Local Administration of Gemcitabine, a Radiation Sensitizer Cervical

Principal Investigator:
Melissa Geller
Contact:
Deborah Biegert
biege001@umn.edu
612-624-8647

WCC 40: A Phase II Study of Carboplatin and Weekly Paclitaxel as Neoadjuvant Chemotherapy Followed by Interval Cytoreduction in Women with Advanced Staged Epithelial Ovarian, Fallopian Tube, and Primary Peritoneal Carcinoma for High Risk Surgical Candidates or Patients Unlikely to be Optimally Surgically Cytoreduced Ovarian, Fallopian, Primary Peritoneal

Principal Investigator:
Melissa Geller
Contact:
Deborah Biegert
biege001@umn.edu
612-624-8647

WCC 38 A Phase II Trial of Induction Carboplatin and Docetaxel Followed by Radiotherapy then Cobnsolidation Chemotherapy with Carboplatin and Docetaxel in Stage III, IV and Recurrent Endometrial Cancer Uterine

Principal Investigator:
Patricia Judson
Contact:
Suann Mitchell
mitch016@umn.edu
612-624-1919

GOG 209 Randomized Phase III Trial of Doxorubicin/ Cisplatin/ Paclitaxel and G-CSF vs. Carboplatin/ Paclitaxel in Patients with Stage III & IV or Recurrent Endometrial Cancer Uterine

Principal Investigator:
Patricia Judson
Contact:
Melissa Spence
spenc206@umn.edu
(612) 624-2620

A Phase II, Multicenter, Randomized, Blinded, Placebo-Controlled Trial of Carboplatin and Gemcitabine Plus Bevacizumab in Patients with Platinum-Sensitive Recurrent Ovary, Primary Peritoneal, or Fallopian Tube Carcinoma (AVF4095g) Ovarian, Fallopian, Primary Peritoneal

Principal Investigator:
Patricia Judson
Contact:
Suann Mitchell
mitch016@umn.edu
612-624-1919

GOG 0218: A Phase III Trial of Carboplatin and Paclitaxel plus Placebo Versus Carboplatin and Paclitaxel plus Concurrent Bevacizumab followed by Placebo versus Carboplatin and Paclitaxel plus Concurrent and Extended Bevacizumab in Women with Newly Diagnosed, Previously Untreated, Suboptimal Advanced Stage Epithelial Ovarian and Peritoneal Primary Cancer Ovarian, Primary Peritoneal

Principal Investigator:
Chung Kyu Lee
Contact:
Diane Mosel
dmosel@umphysicians.umn.edu
612-626-2627

RTOG C-0116: A Two-part Phase I/II Study of Extended Field External Irradiation and Interacavitary Brachytherapy Combined with Chemotherapy (Weekly Cisplatin-Arm 1) and Amifostine (Weekly Cisplatin and Amifostine-Arm 2) in Carcinoma of the Cervix with Positive Para-Aortic or High Common Iliac Lymph Nodes Cervical, Uterine
BREAST PROTOCOL DETAILS PROTOCOL TITLE DISEASE SITE

Principal Investigator:
Arkadiusz Dudek
Contact:
Carrie McCann
mcca0313@umn.edu
612-626-2569

Phase I Study of Bortezomib (Velcade) and Cetuximab (Erbitux) for Patients with Solid Tumors Expressing EGFR Solid Tumors  

Principal Investigator:
Kathryn E Dusenbery
Contact:
Diane Mosel
dmosel@umphysicians.umn.edu
612-626-2627

A Phase 3 Randomized, Open-label Comparative Study of Standard Whole Brain Radiation Therapy with Supplemental Oxygen, with or without concurrent RSR13 (efaproxiral), in Women with Brain Metastases from Breast Cancer Breast

Principal Investigator:
Bruce A Peterson
Contact:
Juliette Gay
gayxx001@umn.edu
612-625-2956

CALGB 40101Cyclophosphamide and Doxorubicin (CA) (4 vs 6 Cycles) Versus Paclitaxel (12 Weeks vs 18 Weeks) as Adjuvant Therapy for Women with Node-Negative Breast Cancer: A 2X2 Factorial Phase III Ramdomized Study Breast

Principal Investigator:
Bruce A Peterson
Contact:
Sharon Donnelly or
Marva Bohen
info@cancer.umn.edu
(612) 624-2620
CTSU/ECOG PAACT-1: Program for the assessment of clinical cancer tests (PACCT-1) trial assigning individualized options for treatment: the TAILORx trial  

Principal Investigator:
Carolyn Torkelson
Contact:
Juliette Gay
gayxx001@umn.edu
612-625-2956

Phase I Clinical Trial of Trametes versicolor in Women with Breast Cancer Breast

Principal Investigator:
Todd Tuttle
Contact:
Juliette Gay
gayxx001@umn.edu
612-625-2956

Twin Cities Brachytherapy Study for Ductal Carcinoma in Situ: A Phase II Trial Breast

Principal Investigator:
Douglas Yee
Contact:
Juliette Gay
gayxx001@umn.edu
612-625-2956

Phase 2 study to investigate the efficacy and safety of ZK-Epothilone (ZK-Epo; ZK219477) in patients with metastatic breast cancer Breast

Principal Investigator:
Douglas Yee
Contact:
Sharon Donnelly or
Marva Bohen
info@cancer.umn.edu
(612) 624-2620
Phase II Study of Naltrexone for the Treatment of Hormone-Refractory, Metastatic Breast Cancer Breast

Principal Investigator:
Douglas Yee
Contact:
Juliette Gay
gayxx001@umn.edu
612-625-2956

A two-arm randomized open label phase 2 study of CP-751, 871 in combination with exemestane versus exemestane alone as a first line treatment for postmenopausal patients with hormone receptor positive advanced breast cancer (Pfizer A4021004) Breast

Principal Investigator:
Douglas Yee
Contact:
Juliette Gay
gayxx001@umn.edu
612-625-2956

Phase II Study of the Trifunctional Bispecific Anti-HER-2/Neu x Anti-CD3 Antibody Ertumaxomab in Patients with HER-2/Neu Overexpressing (3+ or 2+/FISH+) Metastatic Breast Cancer Progressing after Trastuzumab Treatment Breast
   

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