Malcolm Blumenthal, MD

Professor of Medicine
Director, Section of Allergy

Contact Information

Dr. Blumenthal received his medical degree from the University of Minnesota and did his internship and residency at Barnes Hospital in St. Louis, MO. He did further residency training at the University of Minnesota. He received his fellowship training from the University of Michigan and is ABIM and ABAI certified in Allergy and Immunology. Dr. Blumenthal is a Fellow in the AAAAI and ACAAI and a member of many other professional organizations. Dr. Blumenthal's research interests include asthma, atopic disease, and immunogenetics. He has led an active research program including an NIH-funded investigation of the genetics of asthma, an American Lung Association Asthma Clinical Research Center (ALA-ACRC), as well as international collaborative efforts involving Taiwan, Georgia, and India. These investigations have identified some novel asthma and atopy susceptibility loci, evaluated outcomes of various medical regimes involving asthma, and assessed the epidemiology of asthma and atopy.Dr. Blumenthal is also involved in direct allergy education and the delivery of clinical allergy and asthma health care.

Selected Recent Publications:

Jackola DR, Liebeler CL, Willaert R, Luah S-S, Oetting W, King RA, Blumenthal MN. CD14 promoter polymorphisms in atopic families: implications for modulated allergen-specific IgE and IgG1 responses. Int Arch Allergy Immunol. 2006; 139: 217-224.

Wust SK, Blumenthal MN, Corazalla EO, Benson BA, Dalmasso AP. Complement in asthma: sensitivity to activation and generation of C3a and C5a via the different complement pathways. Transl Res.  2006;148(4):157-63.

Webb BT, van den Oord E, Akkari A, Wilton S, Ly T, Duff R, Barnes KC, Carlsen K, Gerritsen J, Lenney W, Silverman M, Sly P, Sundy J, Tsanakas J, von Berg A, Whyte M, Blumenthal M, Vestbo J, Middleton L, Helms PJ, Anderson WH, Pillai SG.  Quantitative linkage genome scan for atopy in a large collection of Caucasian families. Hum Genet. 2006 Nov 14.

Blumenthal MN, Church TR, Adgate JL, Ramachandran G, Fredrickson AL, Ryan AD, Geisser MS. Asthma, atopy, and lung function among racially diverse, poor inner-urban Minneapolis school children. Environmental Research  2007; 103(2): 257-66.

Reilly C, Miller MB, Liu YB, Oetting WS, King RD, Blumenthal MN. Linkage analysis of a cluster-based quantitative phenotype constructed from pulmonary function test data in 27 multigenerational families with multiple asthmatic members. Hum Hered.  2007;64(2):136-145.

N Jing, Pei J, Blumenthal M, Pei D. Complete restoration of cell surface activity of Transmembrane-turcated MT1-MMP by a glycosylphosphatidylinositol anchor: Implication for MT1-MMP-Mediate PROMMP2 activation and collagenolysis in three-dimensions. J Biol Chem. 2007; 282(9):6438-6442.

Jackola DR. Miller MB. Liebeler CL. Blumenthal MN. Search for quantitative trait loci of atopy-associated immune responses using allergen-specific IgG1 as an "endophenotype". Human Immunology 2007; 68(10):839-43.

McSherry C, Blumenthal MN. Definition of an allergen (immunobiology). Clin Allergy Immunol. 2008;21:31-46.