Hyun Kim, MD

Assistant Professor
Contact Information


Clinical Interests

• Pulmonary
• Scleroderma Lung Disease
• Interstitial Lung Disease
• Pulmonary Fibrosis
• Sarcoidosis
• Autoimmune Lung Disease
• Lung Involvement in Collagen Vascular Diseases
  

Clinical Studies

• Scleroderma Lung Disease: A Retrospective Analysis of Clinical, Radiographic and Physiologic Correlations.  Principal Investigator.
• A Double-Blind, Extension Study to Evaluate the Long Term Safety and Efficacy of the Phosphodiesterase Type 5 (PDE5) Inhibitor Tadalafil in the Treatment of Patients with Pulmonary Arterial Hypertension. University of Minnesota Co-Investigator.
• A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Three-Arm Study of the Safety and Efficacy of Pirfenidone in Patients with Idiopathic
• Pulmonary Fibrosis. University of Minnesota Co-Investigator.
• A Phase 1, Open-label, Multi-Center, Single Doise, Dose-Escalating, Safety, Tolerability, and Pharmacokinetic Study of GC1008 in Patients with Idiopathic Pulmonary Fibrosis.  Co-Investigator, University of Minnesota.
• Scleroderma Lung Disease.  Clinico-pathologic-radiologic correlations in scleroderma lung disease.  Principal Investigator.
• The Effect of Pulmonary Rehabilitation in Patients with Idiopathic Pulmonary Fibrosis.  Co-Investigator.
• Effects of Bosentan on Morbidity and Mortality in Patients with Idiopathic Pulmonary Fibrosis – A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group, Event-Driven, Group Sequential, Phase III Study.  Co-Investigator, University of Minnesota.

Recent Honors

• May, 1997 Minneapolis Society of Internal Medicine Cecil J. Watson Award for Outstanding Research Achievement
• July, 2000 University of Minnesota Department of Medicine Young Investigator Award, Active Grant Support, Principal Investigator
• NIH K08 "Integrins and alveolar re-epithelialization" 7/1/1997-6/30/2002, Principal Investigator
• American Lung Association of Minnesota "Mechanisms of HGF-stimulated alveolar epithelial cell motility" 7/1/2000-6/30/2002, Principal Investigator
• Minnesota Medical Foundation "Interaction of chemokines and airway epithelial cells in asthma" 7/1/2000-6/30/2001

Selected Recent Publications

Kim HJ, Henke CA, Ingbar DH.  Integrin mediation of alveolar epithelial cell migration on fibronectin and type I collagen.  Am J Physiol 273 (Lung Cell Mol Physiol 17): L134-L141, 1997.

 Kim HJ, Ingbar DH, and Sammak PS.  Alveolar epithelial cell migration and close contacts are specifically stimulated by fibronectin and hepatocyte growth factor.  In revision.

Kim HJ and Bitterman PB. Peptide growth factors and matrix signals in idiopathic pulmonary fibrosis. In Lung Biology in Health and Disease: Idiopathic Pulmonary Fibrosis, pp. 563-572. Joseph P. Lynch, ed. Marcel Dekker, Inc., New York, NY. 2004.

Kim HJ, and Ingbar DH. Acute respiratory failure. In Pulmonary/Respiratory Therapy Secrets, pp. 459-468. 3rd edition. PE Parsons and JE Heffner, eds. Mosby Elsevier, Philadelphia, PA. 2006.

Kim HJ, E Nelson, T Whelan, and B Segal.  Mycophenolate mofetil (MMF) treatment of scleroderma lung disease following cyclophosphamide.  Oral Presentation, American Thoracic Society meeting, San Francisco, 2007.  Am J Resp Crit Care Med 175 (Abstracts Issue): A497, 2007.

 Whelan TPM, Ramchandani L, and Kim HJ.  Effect of pulmonary rehabilitation on six minute walk test in a well-defined cohort of idiopathic pulmonary fibrosis.  Oral Presentation, American Thoracic Society meeting, San Francisco, 2007.  Am J Resp Crit Care Med 175 (Abstracts Issue): A497, 2007.

Last Updated 10/23/2007