James Leatherman, MD

Professor of Medicine, U of MN
Pulmonary and Critical Care Staff Physician, HCMC
Director of Medical Intensive Care and Director of
    Critical Care Medicine Fellowship Training, HCMC

Board Certification: Internal Medicine, Pulmonary
                                Medicine, Critical Care

Contact Information

Clinical Interests

• Critical Care Medicine and  Mechanical Ventilation

• Pulmonary Medicine Including Asthma, Chronic Obstructive Pulmonary Disease, Interstitial Lung disease

Research Interests

Mechanical Ventilation in Asthma, Neuromuscular Complications in Intensive Care, Hemodynamic Monitoring in Intensive Care

Publications

(For a comprehensive listing of Dr. Leatherman's recent publications refer to PubMed, a service of the National Library of Medicine.)

Emens LA, Asquith JM, Leatherman JM, Kobrin BJ, Petrik S, Laiko M, Levi J, Daphtary MM, Biedrzycki B, Wolff AC, Stearns V, Disis ML, Ye X, Piantadosi S, Fetting JH, Davidson NE, Jaffee EM. Timed sequential treatment with cyclophosphamide, doxorubicin, and an allogeneic granulocyte-macrophage colony-stimulating factor-secreting breast tumor vaccine: a chemotherapy dose-ranging factorial study of safety and immune activation. J Clin Oncol. 2009 Dec 10;27(35):5911-8.

Marinelli WA, Leatherman JW.  Neuromuscular disorders in the intensive care unit.  Crit Care Clin 2002; 18(4):915-29.

Leatherman JW, Shapiro RS.  Overestimation of pulmonary artery occlusion pressure in pulmonary hypertension due to partial occlusion.  Crit Care Med. 2003;31(1):93-7.

Leatherman JW, McArthur C, Shapiro RS.  Effect of prolongation of expiratory time on dynamic hyperinflation in mechanically ventilated patients with severe asthma.  Crit Care Med 2004; 32(7:1542-5.

Qureshi AS, Shapiro RS, Leatherman JW.  Use of bladder pressure to correct for the effect of expiratory muscle activity on central venous pressure.  Intensive Care Med 2007; 33(11):1907-12.

Leatherman JW.  Mechanical ventilation for severe asthma.  Respir Care 2007; 52(11):1460-2. 

Kesler SM, Sprenkle MD, David WS, Leatherman JW.  Severe weakness complicating status asthmaticus despite minimal duration of neuromuscular paralysis.  Intensive Care Med. 2009; 35(1):157-60

Melamed R, Sprenkle MD, Ulstad VK, Herzog CA, Leatherman JW.
Chest. Assessment of left ventricular function by intensivists using hand-held echocardiography. Chest, 2009; 135(6):1416-20.

Abstracts

Bastin-deJong CH, Shapiro RS, Leatherman JW. Use of expiratory change in bladder pressure (_Δ) to correct for the effect of active expiration on end-expiratory CVP (CVPee). Am J Respir Crit Care Med. 2009; 179:A5495.