James Leatherman, MD

Professor of Medicine, U of MN
Pulmonary and Critical Care Staff Physician, HCMC
Director of Medical Intensive Care and Director of
       Critical Care Medicine Fellowship Training, HCMC

Board Certification: Internal Medicine, Pulmonary
                                Medicine, Critical Care
Contact: jim.leatherman@co.hennepin.mn.us

Clinical Interests

• Critical Care Medicine and  Mechanical Ventilation

• Pulmonary Medicine Including Asthma, Chronic Obstructive Pulmonary Disease, Interstitial Lung disease

Research Interests

Mechanical Ventilation in Asthma, Neuromuscular Complications in Intensive Care, Hemodynamic Monitoring in Intensive Care

Publications

Schlesinger PA, Leatherman JW.  Rheumatology. Am J Respir Crit Care Med. 2002; 166(9):1161-5.

Marinelli WA, Leatherman JW.  Neuromuscular disorders in the intensive care unit.  Crit Care Clin 2002; 18(4):915-29.

Leatherman JW, McArthur C, Shapiro RS.  Effect of prolongation of expiratory time on dynamic hyperinflation in mechanically ventilated patients with severe asthma.  Crit Care Med 2004; 32(7:1542-5.

Qureshi AS, Shapiro RS, Leatherman JW.  Use of bladder pressure to correct for the effect of expiratory muscle activity on central venous pressure.  Intensive Care Med 2007; 33(11):1907-12.

Leatherman JW.  Mechanical ventilation for severe asthma.  Respir Care 2007; 52(11):1460-2. 

Kesler SM, Sprenkle MD, David WS, Leatherman JW.  Severe weakness complicating status asthmaticus despite minimal duration of neuromuscular paralysis.  Intensive Care Med. 2009; 35(1):157-60

Melamed R, Sprenkle MD, Ulstad VK, Herzog CA, Leatherman JW.
Chest. Assessment of left ventricular function by intensivists using hand-held echocardiography. Chest, 2009; 135(6):1416-20.

Emens LA, Asquith JM, Leatherman JM, Kobrin BJ, Petrik S, Laiko M, Levi J, Daphtary MM, Biedrzycki B, Wolff AC, Stearns V, Disis ML, Ye X, Piantadosi S, Fetting JH, Davidson NE, Jaffee EM.  Timed sequential treatment with cyclophosphamide, doxorubicin and an allogenic graulocyte-macrophage colony-stimulating factor-secreting breast tumor vaccine: a chemotherapy dose-ranging factorial study of safety and immune activation. J Clin Oncol. 2009 Oct 5. [Epub ahead of print]

Abstracts

Bastin-deJong CH, Shapiro RS, Leatherman JW. Use of expiratory change in bladder pressure (_Δ) to correct for the effect of active expiration on end-expiratory CVP (CVPee). Am J Respir Crit Care Med. 2009; 179:A5495.