Jeffrey B. Rubins, MD

Professor

My clinical activities focus on resident and fellow education, and on sleep apnea and early detection of lung cancer. As medical director for our sleep apnea program, I supervise the evaluation and treatment of approximately 180 patients referred each month with suspected obstructive sleep apnea, using a new approach of unattended cardiopulmonary studies and autotitrating CPAP.

I also  direct the management of 600 patients who are being followed in early lung cancer detection programs. As part of our diagnostic program, we have just acquired a superDimension bronchoscopy system to allow electomagnetic navigation in biopsys of small pulmonary lesions outside the range of traditional bronchoscopy.

My clinical interests derive from my previous research investigations in lung cancer, pleural effusion, and pneumococcal vaccination.

Honors

• President, Minnesota Thoracic Society

• Co-Chair, IRB, Minneapolis VA Medical Center
  

Active Grant Support

• Consultant: Lung Cancer Chemoprevention: isothiocyanate, inositol
  NIH/NIAID, 2005-2010

Selected Recent Publications

Elkayam O, Caspi D, Reitblatt T, Charboneau D, Rubins JB.  The effect of tumor necrosis factor blockade on the response topneumococcal vaccination in patients with rheumatoid arthritis and ankylosing spondylitis.  Semin Arthritis Rheum. 2004; 33(4):283-8.

Sullivan V, Tran T, Holmstrom A, Kuskowski M, Koh P, Rubins JB, Kelly RF.  Advanced age does not exclude lobectomy for non-small cell lung carcinoma. Chest 2005; 128:2671-76.

Janoff EN, Briles DE, Rubins JB. Respiratory bacterial vaccines. In: Mucosal Immunology, 3rd Ed. Boston, Elsevier Academic Press, 2005: 905-922.

Rice KL, Nelson KA, Rubins JB, Arjes S. Unattended cardiopulmonary sleep studies to diagnose obstructive sleep apnea. Fed. Practitioner 2006; 23(5):17-31.

Rubins J, Unger M, Colice GL.  Follow-up and Surveillance of the Lung Cancer Patient Following Curative Intent Therapy: ACCP Evidence-Based Clinical Practice Guideline (2nd Edition). Chest 2007; 132(3): 355S–367.

Nguyen JT, Myers N, Palaia J, Georgopoulos A, Rubins JB, Janoff EN.  Humoral responses to oxidized low-density lipoprotein and related bacterial antigens after pneumococcal vaccine.  Translational Research 2007; 150: 172-9.

Rubins JB, Boulware D, Janoff EN.  Pneumococcal disease in adults. In: Pneumococcal Vaccines:  The Impact of Conjugate Vaccine. Siber G, Klugman K, and Mäkelä H, eds. ASM Press, Washington DC.  2007.

Rubins JB.  The current approach to the diagnosis of pulmonary embolisms: lessons from PIOPED II.  Postgrad Med 2008; in press. 

Last Updated 4/7/2008