Tucker W. LeBien, Ph.D.

Contact Information Phone: 612-626-1422 Fax: 612-626-2696 Email: lebie001@umn.edu Address: MMC 806 Mayo 8806 420 Delaware Minneapolis, MN 55455

Professor

Educational Background

• North Dakota State University, North Dakota (1970), B.S. (Zoology)
• North Dakota State University, North Dakota (1973), M.S. (Bacteriology)
• University of Nebraska Medical Center, Nebraska (1977), Ph.D. (Medical Microbiology – Immunology)
   

Professional Background

• Research Assistant, University of Nebraska Medical Center, Department of Medical Microbiology, Omaha, NE, 1974 – 1977
• Postdoctoral Fellow, University of Minnesota, Department of Laboratory Medicine and Pathology, Minneapolis, MN, 1977 – 1979
• Instructor, University of Minnesota, Department of Laboratory Medicine and Pathology, Minneapolis, MN, 1979 – 1980
• Assistant Professor, University of Minnesota, Department of Laboratory Medicine and Pathology, Minneapolis, MN, 1980 – 1984
• Associate Professor, University of Minnesota, Department of Laboratory Medicine and Pathology, Minneapolis, MN, 1984 – 1989
• Visiting Associate Professor of Pathology, Harvard Medical School, Laboratory of Molecular Immunology, Boston, MA, 1986
• Director of Graduate Studies, University of Minnesota, Pathobiology Graduate Program, Minneapolis, MN, 1988 – 1993
• Professor, University of Minnesota, Department of Laboratory Medicine and Pathology, Minneapolis, MN, 1989 – Present
• Director, University of Minnesota, NIAID Immunology Predoctoral Training Program, Minneapolis, MN, 1989 – 2002
• Chair, Leukemia Task Force/ Leukemia Research Fund, 1994 – Present
• Associate Director for Basic Research, University of Minnesota Cancer Center, Minneapolis, MN, 1994 – Present
• Director, Flow Cytometry Core, 1996 – Present
• Deputy Director, University of Minnesota Cancer Center, Minneapolis, MN, 1997 – 2007
• Director, University of Minnesota, NIH Medical Scientist Training Program, Minneapolis, MN, 2003 – Present
• Director, University of Minnesota, Combined M.D./ Ph.D Program, Minneapolis, MN, 2003 - Present

Professional Memberships

• American Association of Immunologists
• American Association for Cancer Research
• American Society of Hematology
• American Association for the Advancement of Science
• International Society for Experimental Hematology

Professional Honors

• Alumni Achievement Award, North Dakota State University, 2002
• Apogee Enterprises Chair in Cancer Research, 1999 – Present
• Associate Editor, Blood, 1991 – 1997
• Stohlman Memorial Award, Leukemia Society of America, 1989
• McFadden Lectureship, Nebraska Medical Center, 1987
• Short Term Scientific Exchange Award, Leukemia Society of America, 1986
• Award of Excellence, Alison Eberlein Fund, Inc., 1984
• Scholar of the Leukemia Society of America, 19984 – 1989
• Travel Scholarships to: IV Int. Cong. Of Immunology, Paris, 1980; X. Cong. of the Int. Soc. for Experimental Hematology, Munich, 1981; V. Int. Cong. of Immunology, Kyoto, 1983; 3rd National Conference of the Leukemia Society of America, San Diego, 1987.
• National Cancer Institute New Investigator Award, 1980 - 1982

Publications

Dr. LeBien has served on the Editorial Boards for:

• Experimental Hematology, 2002 – 2006
• Blood, 1988 – 1990
• Leukemia, 1987 – 1996
• Leukemia Research, 1985 – 1986
• Journal of Immunology, 1984 – 1988

Books/Chapters

• Burrows PD, LeBien TW, Zhang Z, Davis RS, Cooper MD. The development of human B lymphocytes. In: Molecular Biology of B cells; Honjo T, Alt FW, Neuberger M, eds. 2004. Elsevier Academic Press, pp141-154
• Johnson SE, LeBien TW. Chapter 157: B-cell development. Fetal and Neonatal Physiology. 4th edition, Polin RA, Fox WW, Abman SH, eds. 2008

Peer-Reviewed Articles

• Hermanson D, Addo SN, Bajer AA, Marchant JS, Das SG, Srinivasan B, Al-Mousa F, Michelangeli F, Thomas DD, Lebien TW, Xing C. Dual Mechanisms of sHA 14-1 in Inducing Cell Death through Endoplasmic Reticulum and Mitochondria. Mol Pharmacol. 2009 Jun 26.
• LeBien TW, Tedder TF. B lymphocytes: how they develop and function. Blood. 2008 Sep 1;112(5):1570-80.
• Johnson SE, Shah N, Bajer AA, LeBien TW. IL-7 activates the PI3K/AKT pathway in normal human thymocytes but not normal human B-cell precursors. J Immunol. 2008 Jun 15;180(12):8109-17.
• Johnson SE, Shah N, Panoskaltsis-Mortari A, and LeBien TW. Murine and human IL-7 activate STAT5 and induce proliferation of normal human pro-B cells. 2005. J Immunol 175:7325-7331.

For a complete listing of Dr. LeBien's publications, please see the National Library of Medicine's PubMed Search.