Angela Mortari, Ph.D.

Associate Professor
Mayo Mail Code 366
420 Delaware St. SE
Minneapolis, MN 55455
Phone: (612) 626-1926
Fax: (612) 626-4074
panos001@umn.edu
Preferred method of contact:  Email

Angela Panoskaltsis-Mortari, Ph.D. is an Associate Professor of Pediatrics in the Division of Hematology-Oncology and Blood and Marrow Transplantation. Dr. Panoskaltsis-Mortari is the Director of the Cytokine Reference Laboratory.

Dr. Panoskaltsis-Mortari received her PhD from the University of Western Ontario. She was a post-doctoral fellow in the Department of Pathology at the University of Alabama and a post-doctoral research associate in the Department of Pediatrics at the University of Minnesota. She joined the University of Minnesota faculty in 1995.

Panoskaltsis-Mortari has board certification from the American Board of Medical Laboratory Immunology. She is a member of numerous immunology, pulmonary and hematology professional societies, and the author of nearly 120 articles which have appeared in such publications as Journal of Experimental Medicine, Journal of Clinical Investigation, Blood, Biology of Blood and Marrow Transplantation, American Journal of Physiology (Lung, Cell. & Mol. Physiol.) and Journal of Immunology.

Research Interests

Dr. Panoskaltsis-Mortari laboratory research focuses upon the study of bone-marrow transplant-related lung injury (idiopathic pneumonia syndrome) and the biology of graft-versus-host disease, both of which are major complications causing morbidity and mortality post-BMT. She is also exploring novel methods of enhancing lung repair after transplant using growth factors and multipotential adult stem cells.

Selected Recent Publications:

Kharbanda S, Panoskaltsis-Mortari A, Haddad IY, Blazar BR, Orchard PJ, Cornfield DN, Grewal SS, Peters C, Regelmann WE, Milla CE, Baker KS. Inflammatory cytokines and the development of pulmonary complications after allogeneic hematopoietic cell transplantation in patients with inherited metabolic storage disorders.  Biol Blood Marrow Transplant. 2006; 12:430-437.

Miller JS, Curtsinger J, Berthold M, Malvey K, Bliss RL, Le CT, Fautsch SK, Dudek AZ, Blazar BR, Panoskaltsis-Mortari A. Diminished neo-antigen response to keyhole limpet hemocyanin (KLH) vaccines in patients after treatment with chemotherapy or hematopoietic cell transplantation.  Clin. Immunol. 2005;117:144-151.

Osborn MJ, Panoskaltsis-Mortari A, McElmurry RT, Bell SK, Vignali DAA, Ryan MD, Wilber A, McIvor RS, Tolar J, Blazar BR. A picornaviral 2A-like sequence based tricistronic vector allowing for high level therapeutic gene expression coupled to a dual reporter system.  Mol. Ther. 2005;12:569-574.

Wysocki CA, Panoskaltsis-Mortari A, Blazar BR, Serody JS. Leukocyte migration and graft-versus-host disease.  Blood 2005;105:4191-4199.

Panoskaltsis-Mortari A, Price A, Hermanson JR, Taras E, Lees C, Serody J, Blazar BR. (2004). In vivo imaging of graft-versus-host-disease (GVHD) in mice.  Blood 103:3590-3598.