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Type 1 Diabetes (TrialNet)

Type 1 Diabetes

The University of Minnesota's Division of Pediatric Endocrinology continues a long tradition of being actively involved in type 1 diabetes studies.  The University of Minnesota is a clinical center for TrialNet.  TrialNet is a world wide network of researchers involved in studies looking at the prevention and early treatment of type 1 diabetes.  It is funded by the National Institutes of Health, American Diabetes Association and Juvenile Diabetes Research Foundation.

You are eligible for these studies:

IF YOU

AND

YOU ARE ELIGIBLE FOR

Have a first degree relative (mother, father, sister, brother, child) with type 1 diabetesAre between ages 1 and 45Natural History Study of the Development of Type 1 Diabetes (TrialNet)
Have a second degree relative (cousin, uncle, aunt, niece, nephew, grandparent, or half-sibling) with type 1 diabetesAre between ages 1 and 20Natural History Study of the Development of
Type 1 Diabetes (TrialNet)
 
Have been diagnosed with type 1 diabetes within 3 months of study enrollment, and have one diabetes-related auto-antibodies present at screeningAre between ages 12 and 35

T1DAL (Trial of Inducing Remission in New-Onset Type 1 Diabetes with Alefacept)

This multicenter study is sponsored by the National Institute of Allergy and Infectious Diseases and is supported by the Juvenile Diabetes Research Foundation.  It is investigating the effect of intramuscular injections of the protein alefacpt (Amevive®; Astellas Pharma US Inc.) on halting the destruction of beta cells in new-onset type 1 diabetes patients.  Participants will receive weekly intramuscular injections of 15mg alefacept or placebo for two 12-week periods.

If you are interested in participating in this study or would like to receive additional information, please call Carrie Gibson at (612) 624-5958 or email gibso002@umn.edu


THESE STUDIES ARE NO LONGER ENROLLING

Have had type 1 diabetes for less than 12 weeksAre between ages 6 and 45Canakinumab Study- The Effects of Canakinumab on the Progression of Type 1 Diabetes in New Onset Subjects - No Longer Enrolling
Have had type 1 diabetes for less than 3 monthsAre between ages 6 and 45CTLA 4 (Abatacept) New Onset Study - No Longer Enrolling
Have had type 1 diabetes for less than 90 daysAre between ages 12 and 45DEFEND-2: Phase 3 Trial of Otelixizumab for Young Adults With Newly Diagnosed Type 1 Diabetes Mellitus - No Longer Enrolling
Have had type 1 diabetes for less than 3 monthsAre between ages 3 and 16Effects of Recombinant Human Glutamic Acid Decarboxylase (rhGAD65) Formulated in Alum (GAD-alum) on the Progression of Type 1 Diabetes in New Onset Subjects (TrialNet) - No Longer Enrolling
Have type 1 diabetesAre Mexican American or African AmericanThe Genetics Study (TrialNet) - No Longer Enrolling
Have had Type 1 Diabetes for less than 3 monthsAre between ages 8 and 45MMF/DZB - New Onset Study (TrialNet) - No Longer Enrolling

Have a baby less than 5 months of age

The baby has a first degree relative with type 1 diabetes

Nutritional Intervention to Prevent Type 1 Diabetes Pilot Trial (TrialNet) - No Longer Enrolling

Are a pregnant woman in your 3rd trimester

The expected baby has a first degree relative with type 1 diabetesNutritional Intervention to Prevent Type 1 Diabetes Pilot Trial (TrialNet) - No Longer Enrolling

Have had type 1 diabetes for at least 2 weeks to 20 weeks

Are between the ages of 12 and 35 years

A Phase II, multicenter, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of PROCHYMAL™ (ex vivo cultured adult human mesenchymal stem cells) for the treatment of recently diagnosed type 1 diabetes mellitus (T1DM) - No Longer Enrolling

Have had type 1 diabetes for less than 3 monthsAre between ages 8 and 45Rituximab-New Onset Study (TrialNet) - No Longer Enrolling
Have had type 1 diabetes for less than 12 weeksAre between ages 12 and 35Thymoglobulin (ATG) to Preserve Beta Cell Function in New Onset Type 1 Diabetes - No Longer Enrolling
Have had type 1 diabetes for less than 12 monthsAre between ages 12 and 45TRX4 Therapeutic Evaluation of Different Multi-Dose Regimens in Type 1 Diabetes Mellitus (TTEDD) - No Longer Enrolling

 

 

Contact the Type 1 Diabetes TrialNet Clinical Research Staff

For information on clinical trials in islet transplantation for type 1 diabetes in individuals who have lost the ability to sense low blood sugar levels OR have had a kidney transplant within the last 5 years, please visit our website, www.diabetesinstitute.org


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