Chandy John, M.D., M.S.

Professor
717 Delaware Street SE
Minneapolis, MN 55455
Phone: (612) 625-8383
Fax: (612) 625-7411
ccj@umn.edu
Global Peds Page
 

Chandy John, M.D., M.S., is Professor of Pediatrics and Medicine, Director of the Division of Global Pediatrics, and a member of the Division of Pediatric Infectious Diseases at the University of Minnesota.  Dr. John received his M.D. and completed residency in Internal Medicine and Pediatrics at the University of Michigan, Ann Arbor.  He completed a pediatric infectious disease fellowship at Rainbow Babies & Children's Hospital in Cleveland, Ohio, and received his M.S. in Epidemiology at Case Western Reserve University.  At Rainbow Babies, Dr. John co-directed the Center for International Child Health and held faculty positions in the Division of Pediatric Diseases and the Center for Global Health and Diseases at Case Western.

Dr. John joined the faculty at the University of Minnesota in 2005.  He is an active clinician, educator, and researcher in the Division of Pediatric Infectious Diseases.  He also established the Division of Global Pediatrics, and, with Dr. Cindy Howard, concurrently guided development of a pediatric global health track for pediatric and medicine-pediatrics residents.

Dr. John is internationally recognized for his research studies in malaria immunoepidemiology and pathogenesis, the long-term neurodevelopmental sequelae of infectious diseases, and the interactions between infection, nutrition, and child neurodevelopment.  He has had NIH-funded research studies and/or training grants in Kenya since 1999 and in Uganda since 2003, and has published 75 peer-reviewed research publications and 19 book chapters.

Dr John has served as an appointed member of the Clinical Research and Field Studies study section of the National Insitutes of Health.  He serves on committees in the American Society of Tropical Medicine and Hygiene (Chair, Benjamin H. Kean Travel Fellowship Awards; Council member, American Committee on Clinical Tropical Medicine and Traveler's Health; Member, Standards and Treatment Guidelines and Scientific Program committees); the Pediatric Infectious Diseases Society (International Affairs, and Nominations and Awards committees); and the Pediatric American Societies (Scientific Program committee).  Dr. John is a fellow of the American Academy of Pediatrics, and a member of the American Pediatric Society, the Society for Pediatric Research, and the Infectious Diseases Society of America.

Dr. John's published writing outside of medical research includes essays, poetry, and short stories.

Honors and Awards

• Amplatz Scholar Award, University of Minnesota Department of Pediatrics, 2010
• Emerging Physician Leadership Program, University of Minnesota Medical School, 2008-2011
• Outstanding Faculty Educator, University of Minnesota Department of Pediatrics, 2007
• Outstanding Contribution to Resident Education, Rainbow Babies & Children's Hospital, 2005
• Best Contribution Award for Teaching Excellence, Case Western Reserve University, 2004
• Young Investigator Award, Pediatric Infectious Disease Society, 2004
• Glennan Teaching Scholar Award, Case Western Reserve University, 2002
• AMSA International Health Fellowship, Ilorin, Nigeria, 1989 
• Bronze Beeper Award, Galens Medical Society, University of Michigan, 1989
• Frank H. Robbins Award, University of Michigan Inteflex Program, 1988
• Patrick J. Niland Award, University of Michigan Medical School, 1988

Recent Publications (Out of 75 peer-reviewed research publications)

• Noland GS, Ayodo G, Abuya JS, Hodges JS, Rolfes MAR, John CC.  Decreased prevalence of anemia in highland areas of low malaria transmission after a one-year interruption of transmission.  Clinical Infectious Diseases 2011, in press.
• McCarra MB, Ayodo G, Sumba PO, Kazura JW, Moormann AM, Narum DL, John CC.  Antibodies in Plasmodium falciparum Erythrocyte-binding Antigen-175 Are Associated with Protecion From Clinical Malaria.  Pediatr Infect Dis J. 2011 Aug 3. [Epub ahead of print]. PMCID: pending.
• Bangirana P, Allebeck P, Boivin MJ, John CC, Page C, Ehnvall A, Musisi S.  Cognition, behaviour and academic skills after cognitive rehabilitation in Ugandan children surviving severe malaria: a randomised trial.  BMC Neurology, 2011, 11:96. PMCID: pending.
• Hawkes M, Opoka RO, Namosopo S, Miller C, Thorpe KE, Lavery JV, Conroy AL, Liles WC, John CC, Kain KC.  Inhaled Nitric Oxide for the Adjunctive Therapy of Severe Malaria: Protocol for a Randomized Controlled Trial.  Trials 2011, 12(1):176.  PMCID: pending.
• Bangirana P, Allebeck P, Boivin MJ, John CC, Page C, Ehnvall A, Musisi S.  Cognitive rehabilitation in Ugandan children after severe malaria: effects on cognition, academic achievement and behavior.  BMC Neuroscience, 2011, accepted for publication.  PMCID: pending.
• Hawkes M, Opoka RO, Namasopo S, Miller C, Conroy AL, Serghides L, Kim H, Thampi N, Liles WC, John CC, Kain KC.  Nitric oxide for the adjunctive treatment of severe malaria: Hypothesis and rationale.  Med Hypotheses 2011, in press.  PMCID: pending.
• McCarra M, Ayodo G, Sumba PO, Kazura JW, Moormann AM, Narum DL, John CC.  Antibodies to Plasmodium falciparum erythrocyte binding antigen-175 are associated with protection from clinical malaria.  Ped Inf Dis J 2011, accepted for publication.  PMCID: pending.
• Greenhouse B, Ho B, Hubbard A, Njama-Meya D, Narum DL, Lanar DE, Dutta S, Rosenthal PH, Dorsey G, John CC.  Antibodies to Plasmodium falciparum antigens predict a higher risk of malaria but protection from symptoms once parasitemic.  J Infect Dis 2011, 204(1): 19-26.  PMCID: pending.
• Howard CR, Gladding SP, Kiguli S, Andrews JS, John CC.  Development of a competency-based curriculum in global child health.  Acad Med 2011.
• John CC, Kutamba E, Mugaruru K, Opoka RO.  Adjunctive therapy for cerebral malaria and other severe forms of Plasmodium falciparum malaria.  Expert Rev Anti Infect Ther.  2010 Sep; 8(9): 997-1008.  PMCID: PMC2987235.
• Cohen JM, Ernst KC, Lindblade KA, Vulule JM, John CC, Wilson ML.  Local topographic wetness indices predict household malaria risk better than land-use and land-cover in the western Kenya highlands.  Malar J. 2010 Nov 16;9(1):328.  PMCID: PMC2993734.
• White MT, Griffin JT, Riley EM, Drakeley CJ, Moormann AM, Sumba PO, Kazura JW, Ghani AC, John CC.  Efficacy Model for Antibody-mediated Pre-erythrocytic Malaria Vaccines.  Proc Biol Sci 2010 Oct 13.  PMCID in process.
• Idro R, Marsh K, John CC, Newton CR.  Cerebral malaria: mechanisms of brain injury and strategies for improved neurocognitive outcomes.  Pediatr Res 2010; 68(4): 267-74.  PMCID: PMC3056312.
• Sam-Agudu NA, Greene JA, Opoka RO, Kazura JW, Boivin MJ, Zimmerman PA, Riedesel MA, Bergemann TL, Schimmenti LA, John CC.  TLR9 polymorphisms are associated with altered IFN-y levels in children with cerebral malaria.  Am J Trop Med Hyg 2010; 82(4): 548-55.  PMCID: PMC2844552.
• Kunkel MA, Moertel CL, John CC.  Primary autoimmune neutropenia uncovered by MRSA osteomyelitis.  Inf Dis Clin Pract 2010; 18:279-280.