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Human Hepatocytes and Liver Tissue for Scientific Investigation


National Institute of Diabetes and Digestive and Kidney Diseases 



The Liver Tissue Cell Distribution System (LTCDS) is a National Institutes of Health (NIH) service contract to provide human liver tissue from regional centers for distribution to scientific investigators throughout the United States. These USA regional centers have active liver transplant programs with human subjects approval to provide portions of the resected pathologic liver for which the transplant is performed. Frozen or fresh tissue is available from subcontractors for the usual forms of childhood and adult cirrhosis, fulminate liver failure, chronic rejection, and certain inborn errors of metabolism.  In addition LTCDS provides "normal" human liver tissue (primarily frozen), slides, and tissue blocks, and rarely other liver cell types in culture.

This service also provides isolated hepatocytes only to NIH investigators from "normal" human liver. NIH investigators are always given preference for tissue requests. Supporting letters for NIH new or renewal grant requests can be provided.

Direct inquiries to:

Glenn R. Gourley, M.D.
Principal Investigator, LTCDS

OR

Jane Cattell
LTCDS Coordinator
Pediatric Gastroenterology, Hepatology and Nutrition
East Building, 6th Floor
2450 Riverside Avenue
Minneapolis MN 55454
Telephone: 612-624-1998
Fax: 612-626-0639
E-mail: ltcds@umn.edu 

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