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LaDora V. Thompson, PhD, BS PT
LADORA V. THOMPSON, PhD, BS PT
Program in Physical Therapy, University of Minnesota
366 Children's Rehab Center
612-626-5271
thomp067@umn.edu
Position:
Professor
Education:
University of Wisconsin, B.A. in Education, Marquette University, B.S. in Physical Therapy; Marquette University, Ph.D. in Biological Sciences (Muscle Physiology).
Teaching Responsibilities:
Theory of Therapeutic Exercise; Biology of Aging, Exercise Physiology of the Elderly.
Special interests:
Geriatric Rehabilitation, Aging Skeletal Muscle, Exercise and Inactivity
Other interests:
Skeletal Muscle Physiology, Functional Assessment, Congestive Heart Failure
Recent Publications:
Zhong, S., Chen, C.N., and L.V. Thompson. Sarcopenia of aging: functional, structural and biochemical alterations. Brazilian Journal of Physical Therapy 11(2):91-97, 2007.
Zhong, S. and L.V. Thompson. The roles of myosin ATPase activity and myosin light chain content in the slowing of type II fibers with hindlimb unweighting. Am. J. Physiol. - Cell. 293: C723-C728, 2007.
Harrison, A., Anderson, B., Thompson, L.V., L.K. McLoon. Three-dimensional localization of neuromuscular junctions in normal and botulimum toxin treated adult extraocular muscles. Invest Ophthalmol Vis Sci. 48:3594-3601, 2007.
Meany, D., Xie, H., Thompson, L.V., Arriaga, E.A., and Griffin, T.J. Identification of carbonylated proteins from enriched rat skeletal muscle mitochondria using affinity chromatography-stable isotope labeling and tandem mass spectrometry. Proteomics 7:1150-1163, 2007.
Meany, D., Thompson, L.V., and Arriaga, E.A. Simultaneously monitoring the superoxide in the mitochondrial matrix and extramitochondrial space by micellar electrokinetic chromatography with laser-induced fluorescence. Analytical Chemistry 79(12) pp 4588-4594, 2007.
Warner, H.R. and L.V. Thompson. New approaches to aging research. Reviews in Clinical Gerontology. doi: 10.1017/S0959259807002092, Published online by Cambridge University Press 10 Apr 2007.
Prochniewicz, E, Thompson, L.V. and D.D. Thomas. Age-related decline in actomyosin structure and function, Experimental Gerontology 42(10):931-8, 2007.
Ahmadzadeh, H., Andreyev, D., Arriaga, E.A., and L.V. Thompson. Capillary electrophoresis reveals changes in individual mitochondrial particles associated with skeletal muscle fiber type and age. Journals of Gerontology, 61(12):1211-8, 2006.
Thompson, L.V., Durand, D., Fugere, N.A., Ferrington, D.A. Myosin and actin expression and oxidation in aging muscle. J Appl Physiol 101(6):1581-7, 2006.
Snow, L.M., Lynner C.B., Nielsen, E.M., Neu, H.S., and L.V. Thompson. Advanced glycation end product in diabetic rat skeletal muscle in vivo. Pathobiology 73: 244-251, 2006.
Thompson, L.V. Oxidative stress, mitochondra and mtDNA-mutator mice. Exp. Gerontology 41(12): 1220-1222, 2006.
Zhong, S., Lowe, D.A. and L.V. Thompson. Effects of hindlimb unweighting and aging on rat semimembranosus muscle and myosin. Journal of Applied Physiology 101(3):873-80, 2006.
Fugere, N.A., Ferrington, D.A. and L.V. Thompson. Protein nitration with aging in the rat semimembranosus and soleus muscles. Journals of Gerontology, 61(8):806-12, 2006.
Arriaga, E, Ahmadzadeh, H, and L.V. Thompson. On-column labeling for capillary electrophoretic analysis of individual mitochondria directly sampled from tissue cross sections. Anal Bioanal Chem, 2006 Jan;384(1):169-74. Epub 2005 Nov 30.
Snow, L.M., Sanchez, O.A, McLoon, L., Serfass, R.C. and L.V. Thompson. Myosin heavy chain isoform expression in diabetic rats with peripheral neuropathy. Acta Histochemica, 107(3):221-229, 2005.
Snow, L.M., Sanchez, O.A, McLoon, L., Serfass, R.C. and L.V. Thompson. Effect of endurance exercise on myosin heavy chain isoform expression in diabetic rats with peripheral neuropathy. American Journal of Physical Medicine and Rehabilitation, 84(10):770-9, 2005.
Snow, L.M, McLoon, L., and L.V. Thompson. Adult and developmental myosin heavy chain isoforms in soleus muscle of aging Fischer Brown Norway rat. Anat Rec A Discov Mol Cell Evol Biol. 286(1):866-73, 2005.
Prochniewicz, E, Thomas, D.D., and L.V. Thompson. Age-related decline in actomyosin function. Journal of Gerontology, 60(4):425-43, 2005.
Sanchez, O.A, Snow, L.M., Lowe, D.A., Serfass, R.C., and L.V. Thompson. Effects of endurance exercise-training on single fiber contractile properties of insulin-treated streptozotocin-induced diabetic rats. Journal of Applied Physiology, 99(2) 472-478, 2005.
Husom, A.D., Ferrington, D.A., and L.V. Thompson. Age-related differences in the adaptive potential of type I skeletal muscle fibers. Experimental Geronotology, 40:227-235, 2005.
Ferrington, D.A., A.D. Husom, and L.V. Thompson. Altered proteasome structure, function, and oxidation in aged muscle. FASEB, 19(6):644-6, 2005
D.A. Lowe, A.D. Husom, D.A. Ferrington, and L.V. Thompson. Myofibrillar myosin ATPase activity in hindlimb muscles from young and aged rats. Mech of Ageing and Development, 125:9. 619-627, 2004.
Husom, A.D., Peters, E.A., Kolling, E.A., Fugere, N.A., Thompson, L.V. and D.A. Ferrington. Altered proteasome function and subunit composition in aged muscle. Archives of Biochemistry and Biophysics; 421(1): 67-76, 2004.
Ahmadzadeh, H., Johnson, R., Thompson, L.V., and E Arriaga. Direct sampling from muscle cross-sections for electrophoretic analysis of individual mitochondria. Analytical Chemistry, 76: 315-3211, 2004.
Lowe, D.A., Warren, G.L., Snow, L.M., Thompson, L.V. and D. D. Thomas. Muscle activity and aging affect myosin structural distribution and force generation in rat fibers. J Appl Physiol, 96(2): 498-506, 2004.
Guildner, A., Sheie, M., Shotwell, R., Sparby, T., Thoele, J., Willen, S., ZumBerge, J., and L.V. Thompson. The effects of non-weightbearing on skeletal muscle in older rats: an interrupted bout versus an uninterrupted bout. Biological Research for Nursing, 5 (3):195-202, 2004.
Fox, J., Garber, P., Hoffman, M., Johnson, D., Schaefer, P., Vien, J., Zeaton, C. and L.V. Thompson. Morphological characteristics of skeletal muscles with gender and age. AGING/Clinical and Experimental Research, 15: 264-269, 2003.
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