Professor of Medicine
Don and Pat Garofalo Chair for Preventive Cardiology
Director of Research, Rasmussen Center for Cardiovascular Disease Prevention
Associate Director, Cardiovascular Clinical Trials Center
I am dedicated to helping to improve early detection of cardiovascular disease and consequently trying to look for new effective therapeutic approaches to educate these strategies on a national and international level.
Specialty: Cardiology
Medical School: University of Ghent, Belgium
Residency: University of Ghent, Belgium
Fellowship: University of Ghent, Belgium; Mayo Clinic, Rochester, Minnesota
Doctorate: Biomedical Sciences, University of Ghent, Belgium
Ph.D.: Cardiology, University of Ghent, Belgium
Hospital Management: University of Leuven, Belgium
Clinical Interests: Cardiovascular prevention, hypertension, lipid disorders, vascular disease, heart failure
Research Interests: Arterial mechanics and stiffness, aldosterone, neurohumoral factors, clinical trials events evaluation, intima-media thickness, ambulatory blood pressure monitoring, new parameters for early detection of atherosclerosis, peripheral circulation
Professional Organizations: American College of Cardiology (Fellow); American Heart Association (Fellow); American Society of Hypertension; European Society of Cardiology (Fellow); International Society of Hypertension; International Union of Angiology
Recent Publications:
2004
Mallion JM, Chamontin B, Asmar R, De Leeuw PW, O’Brien E, Duprez D, O’Rourke MF, Rahn KH, Romero R, Battegay E, Hitzenberger G, Safar ME. Twenty-four-hour ambulatory blood pressure monitoring efficacy of perindopril/indapamide first-line combination in hypertensive patients: The REASON study. Am J Hypertension 17:245-251, 2004.
Duprez D, Hirsch AT. The potential role of angiotensin converting enzyme inhibition in peripheral arterial disease. Vasc Med 9:1-6, 2004.
Marron BJ, Tholakanahalli VN, Casey SA, Zenovich AG, Duprez D, Aeppli DM, Cohn JN. Utility of B-Type natriuretic peptide assay in the assessement of symptomatic state in hypertrophic cardiomyopathy. Circulation 109:984-989, 2004.
De Luca N, Mallion JM, O’Rourke MF, O’Brien E, Rahn KH, Trimarco B, Romero R, De Leeuw PW, Hitzenberger G, Battegay E, Duprez D, Sever P, Safar ME. Regression of left ventricular mass in hypertensive patients treated with perindopril/indapamide as a first-line combination: The REASON* echocardiography substudy. J Hypertension 17:660-667, 2004.
Duprez D. HOPE brings hope for the use of ankle-brachial index as cardiovascular risk marker. Eur Heart J 25:1-2, 2004.
White WB, Duprez D. Aldosterone antagonism and arterial stiffness. Hypertension 43:e3:1-2, 2004.
Duprez DA, Kaiser D, Whitwam W, Finkelstein S, Belalcazar A, Patterson R, Glasser S, Cohn J. Determinants of radial artery pulse wave analysis in asymptomatic individuals. Am J Hypertension 17:647-653, 2004.
Clement DL, De Buyzere M, Duprez D. Hypertension in peripheral arterial disease. Curr Pharm Des 10(29):3615-20; 2004.
Duprez DA. Is the female heart more sensitive to aldosterone for early remodeling? Hypertension 43(5):936-7, 2004.
Duprez D. Angiotensin II, platelets and oxidative stress. J Hypertens 22(6):1085-6; 2004.
Matthys J, De Meyere M, Mervielde I, Knottnerus JA, Den Hond E, Staessen JA, Duprez D, De Maeseneer J. Influence of the presence of doctors-in-training on the blood pressure of patients: a randomised controlled trial in 22 teaching practices. J Hum Hypertens 18(11):769-73, 2004.
2005
Zimlichman R, Shargorodsky M, Boaz M, Duprez D, Rahn KH, Rizzoni D, Payeras AC, Hamm C, McVeigh G. Determination of arterial compliance using blood pressure waveform analysis with the CR-2000 system: Reliability, repeatability, and establishment of normal values for healthy European population--the seven European sites study (SESS). Am J Hypertens 18(1):65-71, 2005.
Duprez DA, Somasundaram PE, Sigurdsson G, Hoke L, Florea N, Cohn JN. Relationship between C-reactive protein and arterial stiffness in an asymptomatic population. J Hum Hypertens 19(7):515-9, 2005.
Cohn JN, Duprez DA, Grandits GA. Arterial elasticity as part of a comprehensive assessment of cardiovascular risk and drug treatment. Hypertension 46(1):217-20, 2005.
2006
Swan PJ, Wu FM, Dahle TG, Duprez DA. Extrapericardial cardiac compression syndrome. Int J Cardiol. 2005 Nov 27; [Epub ahead of print]
Pitt B, Fonarow GC, Gheorghiade M, Deedwania PC, Duprez DA. Improving outcomes in post-acute myocardial infarction heart failure: incorporation of aldosterone blockade into combination therapy to optimize neurohormonal blockade. Am J Cardiol. 2006;97(10A):26-33.
Duprez DA. Role of the renin-angiotensin-aldosterone system in vascular remodeling an inflammation: a clinical review. J Hypertens. 2006;24:983-91.
Duprez DA, JN Cohn. Monitoring vascular health beyond blood pressure. Current Hypertension Reports 8:287-91, 2006.
Duprez DA. Heart Rate, an independent predictor for hypertension? J Hypertension 24:1711-1713, 2006.
2007
Duprez DA. Aldosterone and the vasculature: mechanisms mediating resistant hypertension. J Clin Hypertension 9;suppl 1:13-18, 2007.
Duprez DA. Pharmacological interventions for peripheral artery disease. Expert Opin Pharmacother. 8:1465-1477, 2007.
Huck CJ, Bronas UG, Williamson EB, Draheim C, Duprez DA, Dengel DR. Non-invasive measurements of arterial stiffness: Repeatability and interrelationships with endothelial function and arterial morphology measures. Vascular Health and Risk Management 3;1-7, 2007.
Duprez DA, Swingen C, Sih R, Lefebvre T, Kaiser DR, Jerosch-Herold M. Heterogeneous remodeling of the ascending and descending aorta with age. J Hum Hypertension; 21:689-691, 2007.
Duprez DA, Florea N, Jones K, Cohn JN. Beneficial effects of valsartan in asymptomatic individuals with vascular or cardiac abnormalities. J Am Coll Cardiol 50;835-839, 2007.
Duprez DA, Cohn JN. Arterial stiffness as risk factor for coronary artery disease. Curr Atherosclerosis Report 9;139-144, 2007.
Wattanakit K, Folsom AR, Duprez D, Weatherly BD, Hirsch AT. Clinical significance of a high ankle-brachial index: insights from the Atherosclerosis Risk in Communities (ARIC) Study. Atherosclerosis 190:459-464, 2007.
Duprez DA, Cohn JN. Measuring endothelial dysfunction. J Hypertension 25;1513, 2007.
Duprez DA. Does it matter how you lower blood pressure in patients with uncomplicated hypertension? Weighing the evidence. Curr Atherosclerosis Rep 9:352-358, 2007.
Prahbu SJ, Blake D, Duprez DA. Concurrent congenital atrioventricular block, Meckel’s Diverticulum and cerebral palsy in a 19 year old male. Int J Cardiol. 120(1):e18-e20, 2007.
Duprez DA. The eye, the mirror of the heart. Eur Heart J 28;1915-1916, 2007.