William Oetting, Ph.D., Institute of Human Genetics at the University of Minnesota

Assistant Professor
Department of Medicine
MMC 485
Room: 4-136 A
Moos Tower
Minneapolis, MN 55455
Phone: (612) 624-1139
Fax: (612) 624-6645
e-mail: oetti001@umn.edu

Research Interests

Director, DNA Analysis Facility, General Clinical Research Center.

Recent Publications

• Fryer JP, Oetting WS, Brott MJ, King RA. 2001, Alternative splicing of the tyrosinase gene transcript in normal human melanocytes and lymphocytes. Journal of Investigative Dermatology 117:1261-1265.
• Oetting WS, 2002, New insight into Ocular Albinism Type 1 (OA1): Mutations and polymorphisms of the OA1 gene. Human Mutation 19:85-92.
• Oetting WS, Fryer JP, Shiriam S, King RA, 2003, Oculocutaneous albinism type I: The last 100 years. Pigment Cell Research 16:307-11.
• King RA, Willaert RK, Schmidt RM, Pietsch J, Savage S, Brott MJ, Fryer JP, Summers CG, Oetting WS, 2003, MC1R mutations modify the classic phenotype of oculocutaneous albinism type 2 (OCA2). American Journal of Human Genetics 73:638-645.
• King RA, Pietsch J, Fryer JP, Savage S, Brott MJ, Russell-Eggitt I, Summers CG, Oetting WS, 2003, Tyrosinase gene mutations in oculocutaneous albinism (OCA1): Definition of the phenotype. Human Genetics 113:502-13.
• Fryer JP, Oetting WS, King RA. 2003, Identification and characterization of a DNase hypersensitive region of the human tyrosinase gene. Pigment Cell Research 16:679-684.
• Blumenthal MN, Langefeld CD, Beaty TH, Bleeker ER, Ober C, Lester L, Lange E, Barnes KC, Wolf R, King RA, Solway J, Oetting W, Meyers DA, Rich SS for the NHLBI Collaborative Study on the Genetics of Asthma, 2004, A genome-wide search for allergic response (atopy) genes in three ethnic groups: Collaborative Study on the Genetics of Asthma (CSGA). Human Genetics 114:157-64.
• Reish O, Berryman T, Cunningham TC, Sher C, Oetting WS, 2004, Analysis of Family with Two Daughters Affected with Trisomy-X. Chromosome Research 12:125-132.
• Thyagarajan B, Gross M, Folsom AR, Anderson K, Oetting WS, Brott M. 2004, Association of CYP1B1 and CYP19 gene polymorphisms with breast cancer incidence. Cancer Letters 207:183-189.
• Blumenthal MN, Ober C, Beaty TH, Bleeker ER, Langefeld CD, King RA, Cox N, Mathias R, Meyers DA, Oetting W, Rich SS for the CSGA. 2004, Genome scan for mite sensitivity. The Collaborative Study on the Genetics of Asthma (CSGA) Genes and Immunity 5:226-31.
• Young TL, Deeb SS, Ronan SM, Dewan AT, Alvear AB, Scavello GS, Paluru PC, Brott MS, Hayashi T, Holleschau AM, Benegas N, Schwartz M, Atwood LD, Oetting WS, Rosenberg T, Motulsky AG, King RA. 2004, X-linked high myopia associated with cone dysfunction.. Arch Ophthalmol 122:897-908.
• Oetting WS, Garrett SS, Brott M, King RA, 2005, P gene mutations associated with oculocutaneous albinism type II (OCA2). Human Mutation 25:323. (Mutation in Brief #789 (2005) Online) http://www3.interscience.wiley.com/homepages/38515/pdf/789.pdf
• Oetting WS, Setaluri, V, 2005, The Tyrosinase Gene Family, in The Pigmentary System: Physiology and Pathophysiology, 2nd Edition. Nordlund JJ, Boissy R, Hearing V, King R, Oetting WS, Ortonne J-P (eds), Oxford University Press, New York (in press).

Academic Interests:

• Genetics of pigmentation and pigmentation abnormalities.
• Genetic analysis of genes and gene polymorphisms associated with solid organ transplant outcome.
• Genomic and protenomic analysis of UV induced tanning.