MMC 39, D-136 Mayo
420 Delaware St. SE
Minneapolis, MN 55455
612-626-2971 Tel
612-624-8176 Fax
georg001@umn.edu
Michael K. Georgieff, M.D., holds the position of Professor of Pediatrics and Child Psychology and Director of the Division of Neonatology and the Institute of Child Development. He received his M.D. from Washington University in St. Louis, Missouri. He served his internship and residency at The Children’s Hospital of Philadelphia. He followed with a residency in neonatology at the University of Pennsylvania and at the University of Minnesota. In addition to attending on the Neonatal Intensive Care Unit, Dr. Georgieff is director of the NICU Follow-up Clinic, director of Neonatal Nutrition Support Service and director of the Center for Neurobehavioral Development. Dr. Georgieff’s research focuses on fetal/neonatal nutrition, specifically, the effect of fetal/neonatal iron nutrition on brain development and neurocognitive function. He has published in numerous journals, including American Journal of Physiology, Pediatric Research, Journal of Nutrition and Journal of Pediatrics. He has written and contributed to a number of book chapters and has over 100 published papers.
Center for Neurobehavioral Development
Lab of Drs. Michael Georgieff and Raghavendra Rao
Institute of Child Development
CURRICULUM VITAE FOR MICHAEL K. GEORGIEFF, M.D. (last revised 12/6/07)
EDUCATION
College
Yale College; 1971-1975 B.A. (Psychology); New Haven, Connecticut
Medical School
Washington University; 1975-1979 M.D.; St. Louis, Missouri
Postgraduate Training
1979-1981 Intern and Resident; The Children’s Hospital of Philadelphia; Philadelphia, Pennsylvania
1981-1982 Assistant Chief Resident Physician; The Children’s Hospital of Philadelphia; Philadelphia, Pennsylvania
1982-1983 Fellow in Neonatology; Division of Neonatology; The Children’s Hospital of Philadelphia and Department of Pediatrics; University of Pennsylvania School of Medicine; Philadelphia, Pennsylvania
1983-1984 Fellow in Neonatology; Division of Neonatology, Department of Pediatrics; University of Minnesota Hospital; Minneapolis, Minnesota
BOARD CERTIFICATION
1984 Board Certified in Pediatrics, American Board of Pediatrics (5/7/84)
1985 Board Certified in Neonatology, American Board of Pediatrics (10/18/85)
SPECIALTY CERTIFICATION
1980 Diplomate, National Board of Medical Examiners
1984 Diplomate, American Board of Pediatrics
LICENSURE
1980 Pennsylvania - inactive
1984 Minnesota
ACADEMIC APPOINTMENTS
1982-1983 Clinical Instructor; Department of Pediatrics; University of Pennsylvania School of Medicine; Philadelphia, Pennsylvania
1983-1985 Clinical Instructor; Department of Pediatrics and Family Practice; University of Minnesota School of Medicine; Minneapolis, Minnesota
1985-1986 Instructor, Department of Pediatrics; University of Minnesota School of Medicine; Minneapolis, Minnesota
1986-1991 Assistant Professor, Department of Pediatrics; University of Minnesota School of Medicine; Minneapolis, Minnesota
1991-1998 Associate Professor, Department of Pediatrics; University of Minnesota School of Medicine; Minneapolis, Minnesota
1997-1998 Associate Professor, Institute of Child Development; University of Minnesota College of Education; Minneapolis, Minnesota
1998- Professor, Department of Pediatrics and Institute of Child Development; University of Minnesota Schools of Medicine and Education; Minneapolis, Minnesota
1999- Co-Director and Founder, Center for Neurobehavioral Development; University of Minnesota; Minneapolis, Minnesota
2001 Full Member, Graduate Program in Neuroscience; University of Minnesota; Minneapolis, Minnesota
STAFF APPOINTMENTS
1984-1986 Staff Neonatologist, Associate Director of Newborn Intensive Care Unit, North Memorial Medical Center, Robbinsdale, Minnesota
1985- Staff Neonatologist, Fairview-University Medical Center, Minneapolis, Minnesota
1985 Director of Neonatal Intensive Care Follow-Up Clinic, Fairview-University Medical Center, Minneapolis, Minnesota
1985- Director, Neonatal Nutrition Support Service, Fairview-University Medical Center, Minneapolis, Minnesota
1986- Consultant, International Adoption Clinic, Fairview-University Medical Center, Minneapolis, Minnesota
1991-1993; Director, Neonatal Intensive Care Unit, University of Minnesota Hospital and Clinic,1994-1995 Minneapolis, Minnesota
TEACHING RESPONSIBILITIES (for complete listing see Education Section)
University of Minnesota School of Medicine
Ongoing teaching of neonatology fellows, pediatric residents and medical students during daily work-teaching rounds on the Neonatal Intensive Care Unit, the NICU Follow-Up Clinic and the Nutrition Support Service. Lecture on nutrition for the low-birth-weight infant as part of Resident Teaching Conferences. Yearly two-lecture series on Pediatric Nutrition for Human Nutrition course (first-year medical students).
University of Minnesota School of Education and Human Development
Seminar on Cellular and Molecular Neuroscience (Child Psy) and co-leader Biofoundation of Behavior (Child Psy)
DIVISIONAL RESPONSIBILITIES
1985-1995 Director, NICU Follow-Up Clinic, University of Minnesota Hospital and Clinic
1987-1998 Director, Neonatal-Perinatal Fellowship Program, University of Minnesota
1991-1993; 1994-1995 Director, Neonatal Intensive Care Unit
1995- Director, NICU Follow-up Clinic, Fairview-University Medical Center
OTHER PROFESSIONAL ACTIVITIES
Hospital Committees
1981-1982 Graduate Education Committee, Houseofficer, Representative and Member, The Children’s Hospital of Philadelphia
1984-1985 Perinatal Committee and Infant Care Review Committee, North Memorial Medical Center
1985-1987 Infant Care Advisory Committee, University of Minnesota Hospital and Clinic
1987-1989 Graduate Education Committee, Intercollegiate Nutrition Consortium, University of Minnesota Hospital and Clinic
1991-1994 Biomedical Ethics Committee, University of Minnesota Hospital and Clinic
1994- Consultant to Biomedical Ethics Committee, University of Minnesota Hospital and Clinic
1992-1996 Pharmacy and Therapeutics Committee, University of Minnesota Hospital and Clinic
Department Committees
1989-2000 Continuing Medical Education Committee, Department of Pediatrics, University of Minnesota
1990-2000 Educational Policy Committee, Department of Pediatrics, University of Minnesota
1994- Faculty Development Committee, Department of Pediatrics, University of Minnesota
1999- Promotions Committee, Department of Pediatrics, University of Minnesota
2000- Research Council, Department of Pediatrics, University of Minnesota
Academic Health Center Committees
2003- AHC Faculty Consultation Committee to the Vice-Provost
Membership in Professional and Scientific Societies
1979 Alpha Omega Alpha
1984 Hennepin County Medical Society
1984 Minnesota Medical Association
1984 American College of Nutrition
1985 American Academy of Pediatrics
1985 American Federation of Clinical Research
1987 Pediatric Council, American College of Nutrition
1988 Society for Pediatric Research
1993 Committee on Nutrition, American Academy of Pediatrics
1993 Perinatal Research Society- Pediatric Council (2000-2003)
1998 FASEB
2001 American Pediatric Society
REVIEWER--JOURNALS
1988 Pediatrics
1988 Journal of Pediatrics
1989 Diabetes
1991 New England Journal of Medicine
1992 Journal of the American College of Nutrition
1992 Pediatric Research
1993 Journal of Laboratory and Clinical Medicine
1994 Acta Paediatrica Scandinavica
1995 Archives of Pediatrics and Adolescent Medicine
1995 Child Development
1996 Applied Developmental Science
2000 American Journal of Physiology
2000 Journal of Pediatric Gastroenterology and Nutrition
2002 Developmental Psychopathology
2003 Developmental Neuroscience
2003 Journal of Neuroscience Research
2003 Brain Research
REVIEWER--SOCIETIES
1993 Society for Pediatric Research: Abstract Reviewer and Moderator for Neonatal Nutrition Society and Metabolism Section
1996 Society for Pediatric Research: Abstract Reviewer and Moderator for Neonatal Nutrition and Metabolism Section
1997 Society for Pediatric Research: Abstract Reviewer and Moderator for Neonatal Nutrition and Metabolism Section
1999 Society for Pediatric Research: Abstract Reviewer and Moderator for Neonatal Nutrition and Metabolism Section
2000 Society for Pediatric Research: Abstract Reviewer and Moderator for Neonatal Nutrition and Metabolism Section
2001 Society for Pediatric Research: Abstract Reviewer and Moderator for Neonatal Nutrition and Metabolism Section
REVIEWER--GRANTING AGENCIES
1995 National Institutes of Health (NICHD): Ad Hoc Reviewer
1997 National Institutes of Health: Behavioral Medicine Study Section
2000 Social Sciences and Humanities Research Council of Canada; National Institutes of Health: Nutrition Study Section (temporary member)
2001 National Institutes of Health: Nutrition Study Section (permanent member)
AWARDS
1985-86 Outstanding Faculty Educator (honorable mention)
1987-88 Outstanding Faculty Educator
1988-89 Outstanding Faculty Educator (honorable mention)
1989-90 Outstanding Faculty Educator (honorable mention)
1990-91 Outstanding Faculty Educator
1991-92 Outstanding Faculty Educator
1992-93 Outstanding Faculty Educator (honorable mention)
2000-01 Outstanding Faculty Educator (honorable mention)
MENTORSHIPS
Neonatal Fellows
Uma Chockalingam (1985-1986)
Raye-Ann deRegnier (1989-1991)
Catharine Davis (Petry) (1990-1992)
Theresa M. Wahlig (1991-1993)
Sixto F. Guiang, III (1991-1993)
Raghavendra Rao (1995-1998)
Marissa de Ungria (1996-1999)
Danna Premer (1996-2000)
Asha Jyothi (1999-2001,2003)
Andras Kovacs (2000-2002)
Medical Students
Mary A. Eaton
Jennifer Merchant
Kelly Flanagan
Heather McKay
Elaine Ong
Daniel Sullivan
Kimberly Smith
April Hurd
Jenni Bradley
Graduate Students (Primary mentor)
Lyric Jorgenson (Neuroscience)
Adam Schmidt (Psychology)
Erik Carlson (Neuroscience, M.D./Ph.D.)
Undergraduate Students
Jennifer Merchant
Kelly Flanagan
Kyia Gordon
Lance Schwandt
Heather McKay
Joseph McGlaughlin
Davis Sands
Ann Wittinger
Peggy Wu
Michelle Ellefson
Quoc-Hung Tran
Karin Holmquist
Sara Baker
Mae Yang
Jennifer Welle
Thanh Le
Kelly Casperson
Kelly Faldow
Vanessa Vogel
RESEARCH ACTIVITIES
My primary research focuses on the effect of fetal/neonatal iron nutrition on brain development and neurocognitive function. I also co-direct the Center for Neurobehavioral Development and am the director of the Infant and Child Development Core for the GCRC.
GRANTS
Past
1. Georgieff MK, Cerra F. “Hormonal Regulation of Rapid Turnover Protein Synthesis in Rat Hepatocytes.” $7500; 4/1/86-3/31/87. Minnesota Medical Foundation.
2. Georgieff MK. “Steroid Regulation of Vitamin A Status in Rats.” $6,387; 9/1/88-8/31/89. Minnesota Medical Foundation.
3. Stoeckeler J, Georgieff MK. “Lap-Top Computer Application in the NICU to Increase Precision for Fluid and Caloric Assessment.” $2,000; 3/15/89-3/14/90. Minnesota Medical Foundation.
4. Palazzo R, Wangensteen OD, Johnson DE, Georgieff MK. “The Effect of Growth Factors on the Repair of Acute Lung Injury.” $11,943; 1989-1990. Viking Children’s Fund.
5. Georgieff MK, Johnson DE, Greenberg JM. “High-Performance Liquid Chromatography for Vitamin A Analysis.” $7,500; 5/1/90-4/30/91. Minnesota Medical Foundation.
6. Georgieff MK. “Hematologic and Cytochrome Enzyme Dysfunction in Infants of Diabetic Mothers.” $9,900; 7/26/87-6/30/88. Ross Laboratories.
7. Georgieff MK. “Minnesota Center for Research on Developmental Disabilities.” PI: Susan Hupp, Allen Levine. $1,762,137; 8/1/89-7/31/94. NIH-NICHD. Role: Core Investigator.
8. Georgieff MK, Gatto C, Boros SJ. “The Neonatal Infant Research Center Project: Nutritional Modification of Neonatal Pulmonary and Developmental Outcome.” PI: SJ Boros, M.D. $75,000; 9/1/90-8/31/93. Hugh J. Anderson Foundation. Role: Collaborator.
9. Georgieff MK. “An Evaluation of a Liquid Hydrolysate Infant Formula and Premature Formula in Low Birth Weight Infants: Effects on Body Composition.” $10,000; 10/1/90-9/1/91. Mead Johnson Nutritional Division.
10. Georgieff MK, Berry S. “Tissue Iron Deficiency Following Fetal Hyperinsulinemia.” $2,500; 5/1/91-4/30/92. Minnesota Medical Foundation.
11. Georgieff MK, Eaton M. “Neonatal Cardiac Sequelae of Fetal Iron Deficiency.” $14,000; 7/1/91-6/30/92. American Heart Association Student Research Fellowship Award.
12. Georgieff MK, Berry S. “Tissue Iron Deficiency Following Fetal Hyperinsulinemia.” $9,247; 6/1/91-5/31/92. Viking Children’s Fund.
13. Georgieff MK. “Duration and Severity of Iron Deficiency in Infants of Diabetic Mothers.” $10,000; 1/1/92-12/31/93. Ross Laboratories.
14. Georgieff MK, Johnson DE, Berry SB. “Neonatal Iron Deficiency in Infants of Diabetic Mothers.” $100,000; 10/1/92-9/30/94. NIH-NICHD, Shannon Award.
15. Jyonouchi H, Georgieff MK. “Studies on the Effects of Breast Milk and Nucleotide Supplemented Infant Formula on Maturation of Immune System in Early Infancy.” $8,400; 8/1/92-7/31/95. Wyeth-Ayerst Research Laboratories. Role: Collaborator.
16. Guiang SF III, Georgieff MK, Kannan MS. “Long-term Effects of Intrauterine Hypoxemia and Iron Depletion on Cardiac Contractility.” $10,205; 7/1/94-6/30/95. Viking Children’s Fund. Role: Co-investigator.
17. Georgieff MK, Nelson CA. “Neurophysiologic Assessment of At-Risk Newborns.” $10,000; 1/1/98-12/31/98. Minnesota Medical Foundation. Role: PI
18. Nelson CA, Georgieff MK, deRegnier RA. “Neurophysiologic Assessment of At-Risk Newborns. Diagnostic Methods to Assess Neurologic Integrity in Newborns.” $618,000; 1/1/95-12/30/98. NINDS (NIH) 1 RO1-NS 34458-04. Role: Co-Principal Investigator.
19. Georgieff MK. “Neonatal Iron Deficiency in Infants of Diabetic Mothers.” $484,054; 12/1/94-11/30/99. NICHD, NIH 1R29HD29421-05. Role: Principal Investigator. 50% Effort
20. Gunner M, Georgieff MK, et al. “Center for the Study of Neurobehavioral Development in the Context of Adversity.” $99,844; 7/1/97-6/30/00. University of Minnesota New Initiates in Interdisciplinary Research and Postbaccalaureate Education Program. Role: Director, Pediatric Health Assessment Core. 5% Effort.
Presently Funded
1. Nelson CA, Georgieff MK, deRegnier RA. “Neurophysiologic Assessment of At-Risk Newborns. Diagnostic Methods to Assess Neurologic Integrity in Newborns.” $1,951,265; 5/1/99-4/30/04. NINDS (NIH) 2 RO1-NS 34458-04. Role: Co-Principal Investigator. 20% effort.
2. Georgieff MK. “Neonatal Iron Deficiency.” $1,556,548; 2/12/00-12/31/04. NICHD, NIH 2 R01 HD29421. Role: Principal Investigator. 40% effort.
3. Moller J, Georgieff MK, et al. “University of Minnesota CHRC-Molecular Models of Organogenesis.” $1,406,795; 9/1/00-8/31/05. NICHD. Role: Recruitment Officer. 10% effort.
4. Lozoff B, et al. “Iron Deficiency in Early Childhood.” 7/1/99-6/30/05. NICHD. PO1 HD39386-01A1. Role: Collaborator. 5% effort years 4 and 5.
5. Moldow C. General Clinical Research Center. $147,499; 4/1/02-11/30/04. NIH. 3 MO1 RR00400-34S1S2. Role: Infancy Core Director. 15% effort.
6. Georgieff MK. Development of a Genetic Model of Perinatal Iron Deficiency in the Hippocampus. $15,000; 7/1/03-6/30/04. Minnesota Medical Foundation. Role: Principal Investigator. 3% effort.
BIBLIOGRAPHY
Articles Published and Accepted for Publication
1. Georgieff MK, Hoffman JS, Pereira GR, Bernbaum JC, Hoffman-Williamson M. The effect of neonatal caloric deprivation on head growth and one-year developmental status in preterm infants. J Pediatr 107:581-587, 1985.
2. Georgieff MK, Sasanow SR, Mammel MC, Ophoven J, Pereira GR. Cord prealbumin values in newborn: Effect of prenatal steroids, pulmonary maturity and size for dates. J Pediatr 108:972-976, 1986.
3. Georgieff MK, Hoffman-Williamson M, Daft A, Bernbaum JC. Abnormal truncal muscle tone as a useful early marker for developmental delay in low birth weight infants. Pediatrics 77:659-663, 1986.
4. Georgieff MK, Bernbaum JC. Abnormal shoulder girdle muscle tone in premature infants during the first 18 months of life. Pediatrics 77:664-669, 1986.
5. Sasanow SR, Georgieff MK, Pereira GR. Mid-arm circumference and mid-arm:head circumference ratio: Standard curves for anthropometric assessment of newborn nutritional status. J Pediatr 109:311-315, 1986.
6. Georgieff MK, Sasanow SR, Mammel MC, Pereira GR. Mid-arm circumference/head circumference ratios for the identification of symptomatic LGA, AGA and SGA newborn infants. J Pediatr 109:316-321, 1986.
7. Georgieff MK, Belani K, Johnson DE, Thompson TR, Ferrieri P. Fulminant hepatic necrosis and death in an infant with perinatally acquired echovirus 21 infection. Pediatr Infec Dis 6(1):71-73, 1987.
8. Chockalingam U, Murphy E, Ophoven JC, Georgieff MK. The influence of gestational age, size for dates and prenatal steroids on cord transferrin in newborn infants. J Pediatr Gastroenterol Nutr 6:276-280, 1987.
9. Chockalingam UM, Murphy E, Ophoven JC, Weisdorf SA, Georgieff MK. Cord transferrin and ferritin levels in newborn infants at risk for prenatal uteroplacental insufficiency and chronic hypoxia. J Pediatr 111:283-286, 1987.
10. Georgieff MK, Sasanow SR, Pereira GR. Serum transthyretin levels and protein intake as predictors of weight gain velocity in premature infants. J Pediatr Gastroenterol Nutr 6:775-779, 1987.
11. Georgieff MK, Sasanow SR, Chockalingam UM, Pereira GR. A comparison of the mid-arm circumference:head circumference ratio and ponderal index for the evaluation of newborn infants after abnormal uterine growth. Acta Pediatr Scand 77(2):214-219, 1988.
12. Georgieff MK, Chockalingam UM, Sasanow SR. The effect of antenatal betamethasone exposure on nutritional protein and fat-soluble vitamin levels in premature infants. J Pediatr Gastroenterol Nutr 7:713-718, 1988.
13. Georgieff MK. Commentary on “Survival after cardiopulmonary resuscitation in babies of very low birth weight.” Critical Care Outlook 1(5):6, 1988.
14. Georgieff MK, Mills MM, Bhatt P. Validation of two scoring systems which assess the degree of physiologic instability in critically ill newborn infants. Crit Care Med 17:17-21, 1989.
15. Georgieff MK, Mills MM, Lindeke L, Iverson S, Johnson DE, Thompson TR. Changes in nutritional management and outcome of very-low-birth-weight infants. AJDC 143:82-85, 1989.
16. Georgieff MK, Mammel MC, Mills MM, Gunter EW, Johnson DE, Thompson TR. The effect of postnatal steroid administration of serum vitamin A concentrations in newborn infants with respiratory compromise. J Pediatr 114:301-304, 1989.
17. Georgieff MK, Mills MM, Zempel CE, Chang P-N. Catch-up growth, body composition and body proportionality of infants one year after newborn intensive care. J Pediatr 114:288-292, 1989.
18. Ferrara TB, Georgieff MK, Ebert J, Fisher J. Routine use of Dexamethasone for the prevention of postextubation respiratory distress. J Perinatol 9(3):287-290, 1989.
19. Georgieff MK, Amarnath UM, Murphy EA, Ophoven JJ. Serum transferrin levels and longitudinal assessment of protein-energy status in preterm infants. J Pediatr Gastroenterol Nutr 8:234-239, 1989.
20. Georgieff MK, Amarnath UM, Sasanow SR, Ophoven JJ. Mid-arm circumference and mid-arm circumference:head circumference ratio for assessing longitudinal growth in hospitalized preterm infants. J Am Coll Nutr 8:477-483, 1989.
21. Amarnath UM, Ophoven JC, Mills MM, Murphy EA, Georgieff MK. The relationship between decreased iron stores and neonatal hypoglycemia in large-for-dates newborn infants. Acta Pediatr Scan 78:538-543, 1989.
22. Georgieff MK, Widness JA, Mills MM, Stonestreet BS. The effect of prolonged intrauterine hyperinsulinemia on iron utilization in fetal sheep. Pediatr Res 26:467-469, 1989.
23. Johnson DE, Georgieff MK. Pulmonary neuroendocrine cells, their secretory products and their potential roles in health and chronic lung disease in infancy. Am Rev Resp Dis 140:1807-1812, 1989.
24. Georgieff MK, Amarnath UM, Mills MM. Determinants of arm muscle and fat accretion during the first postnatal month in preterm newborn infants. J Pediatr Gastroenterol Nutr 9:219-224, 1989.
25. Zach TL, Steinhorn RH, Georgieff MK, Mills MM, Green TP. Leukopenia and infectious complications in critically ill newborn infants: Effects of extracorporeal membrane oxygenation. J Pediatr 116:440-443, 1990.
26. Georgieff MK, Landon MB, Mills MM, Hedlund BE, Faassen AE, Schmidt RL, Ophoven JJ, Widness JA. Abnormal iron distribution in infants of diabetic mothers: Spectrum and maternal antecedents. J Pediatr 117:455-461, 1990.
27. Georgieff MK, Radmer WJ, Sowell AL, Yeager PR, Blaner WS, Gunter EW, Johnson DE. The effect of glucocorticosteroids on serum, liver and lung vitamin A and retinyl ester concentrations. J Pediatr Gastroenterol Nutr 13:376-382, 1991.
28. Georgieff MK, Kassner RJ, Radmer WJ, Berard DJ, Doshi SR, Stonestreet BS. The effect of in utero insulin exposure on tissue iron status in fetal rats. Pediatr Res 31:64-67, 1992.
29. Georgieff MK, Schmidt RL, Mills MM, Radmer WJ, Widness JA. Fetal iron and cytochrome c status after intrauterine hypoxemia and erythropoietin administration. Am J Physiol 262:R485-R491, 1992.
30. Tuchman M, Georgieff MK. Transient hyperammonemia of the newborn: A vascular complication of hyaline membrane disease? J Perinatol 12:234-236, 1992.
31. Petry CD, Eaton MA, Wobken JD, Mills MM, Johnson DE, Georgieff MK. Iron deficiency of liver, heart, and brain in newborn infants of diabetic mothers. J Pediatr 121:109-114, 1992.
32. Johnson DE, Miller LC, Iverson S, Thomas W, Franchino B, Dole K, Kiernan MT, Georgieff MK, Hostetter MK. The health of children adopted from Romania. JAMA 268:3446-3451, 1992.
33. Veng-Pedersen P, Modi NB, Widness JA, Pereira LM, Schmidt RL, Georgieff MK. A system approach to pharmacodynamics V. Plasma iron mobilization by endogenous erythropoietin in the sheep fetus. Evidence of threshold response in spontaneous hypoxemia. J Pharm Sci 82:804-808, 1993.
34. Guiang SF, III, Widness JA, Flanagan K, Schmidt RL, Radmer WJ, Georgieff MK. The effect of fetal hypoxemia on ovine myocardial and skeletal muscle myoglobin. J Dev Physiol 19:99-104, 1993.
35. Jyonouchi H, Zhang L, Georgieff MK, Tomita Y. Immunomodulating actions of nucleotides. Enhancement of Ig production by human cord blood lymphocytes. Pediatr Res 34:565-571, 1993.
36. Wahlig TM, Gatto CW, Boros SJ, Mammel MC, Georgieff MK. The metabolic response of preterm infants to variable degrees of respiratory illness. J Pediatr 124:283-288, 1994.
37. Pereira GR, Baumgart S, Bennett MJ, Stallings VA, Georgieff MK, Hamosh M, Ellis L. High fat formula for premature infants with bronchopulmonary dysplasia: Metabolic, pulmonary and nutritional studies. J Pediatr 124:605-611, 1994.
38. Petry CD, Eaton MA, Wobken JD, Seybold VS, Johnson DE, Georgieff MK. Placental transferrin receptor localization and binding characteristics in diabetic pregnancies characterized by increased fetal iron demand. Am J Physiol 267 (Endocrinol Metab 30):E507-E514, 1994.
39. Georgieff MK. Assessment of large and small for gestational age newborn infants using growth curves. Pediatr Ann 24:1-9, 1995.
40. Georgieff MK, Mills MM, Gordon K, Wobken JD. Reduced neonatal liver iron concentrations following uteroplacental insufficiency. J Pediatr 127:308-311, 1995.
41. Georgieff MK, Petry CE, Wobken JD, Oyer CE. Liver and brain iron deficiency in newborn infants with bilateral renal agenesis (Potter’s syndrome). Pediatr Pathol 16:509-519, 1996.
42. Georgieff MK, Mills MM, Gomez-Martin O, Sinaiko AR. Blood pressure in premature and full-term infants from birth to four months. Pediatr Nephrol 10:152-155, 1996.
43. deRegnier RA, Guilbert T, Mills MM, Georgieff MK. Early body composition changes and growth failure in premature infants with bronchopulmonary dysplasia. J Nutr 126:168-175, 1996.
44. Peters C, Georgieff MK, deAlacron P, Widness JA. Effect of chronic erythropoietin administration on plasma iron in newborn lambs. Biol Neonate 70:218-228, 1996.
45. deRegnier RA, Georgieff MK, Nelson CA. Cognitive event-related brain potentials in four-month-old infants at risk for neurodevelopmental impairments. Dev Psychobiol 30:11-28, 1997.
46. Smith KM, Wahlig TM, Bing DR, Georgieff MK, Boros SJ, Mammel MC. Lower respiratory rates without decreases in oxygen consumption during neonatal synchronized intermittent mandatory ventilation. Intensive Care Med 23:463-468, 1997.
47. Georgieff MK, Petry CD, Mills MM, McKay H, Wobken JD. Increased N-glycosylation and reduced transferrin binding capacity of transferrin receptor isolated from placentas of diabetic mothers. Placenta 18:563-568, 1997.
48. Guiang SF III, Georgieff MK, Schmidt RL, Lambert DJ, Widness JA. Intravenous iron supplementation effect on tissue iron and hemoproteins in chronically phlebotomized lambs. Am J Physiol 273:R2124-2131, 1997.
49. Georgieff MK, Work Group on Breastfeeding of the American Academy of Pediatrics. Breastfeeding and the use of human milk. Pediatrics 100: 1035-1039, 1997.
50. Lindeke LL, Mills MM, Georgieff MK, Tanner ME, Wrbsky PM. Health, growth and use of community services in NICU graduates at early school age. J Pediatr Health Care 12:299-304, 1998.
51. Georgieff MK. Intrauterine growth and neurodevelopment. J Pediatr 133:3-5. 1998.
52. Guiang SF III, Eaton MA, Merchant JL, Flanagan KB, Gordon KL, Georgieff MK. Intracardiac iron redistribution in newborn guinea pigs following isolated and combined fetal hypoxemia and fetal iron deficiency. Can J Physiol Pharm 76:930-936, 1999.
53. Rao R, Sullivan D, Wu P, Wobken JD, Nelson CA, Georgieff MK. Perinatal brain iron deficiency increases the vulnerability of rat hippocampus to hypoxic-ischemic insult. J Nutr 129:199-206, 1999.
54. Georgieff MK, Liebold EA, Wobken JD, Berry SA. Increased placental iron-regulatory protein-1 expression in diabetic pregnancies complicated by fetal iron deficiency. Placenta 20:87-93, 1999.
55. Luciana M, Lindeke L, Georgieff MK, Mills MM, Nelson CA. Neurobehavioral evidence for working memory deficits in school-aged children with histories of neonatal intensive care treatment. Dev Med Child Neurol. 41:521-533, 1999.
56. Georgieff MK. Committee on Nutrition of the American Academy of Pediatrics. Iron Fortification of Infant Formulas. Pediatrics 104:119-123, 1999.
57. DeHaan M, Georgieff MK, Nelson CA, Bauer P. Memory for event sequences in low-risk toddlers born between 27-42 weeks of gestation. Dev Med Child Neurol 42:304-312, 2000.
58. Mrozek J, Georgieff MK, Blazar B, Mammel MC, Schwarzenberg SJ. Neonatal sepsis: Effect on protein and energy metabolism. J Perinatol 20:96-100, 2000.
59. de Ungria M, Rao R, Wobken JD, Luciana M, Nelson CA, Georgieff MK. Perinatal iron deficiency decreases cytochrome c oxidase activity in selective regions of neonatal rat brain. Pediatr Res 48:169-176, 2000.
60. Nelson CA, Wewerka S, Thomas K, Tribby-Walbridge S, deRegnier RA, Georgieff MK. Neurocognitive sequelae of infants of diabetic mothers. Behav Neurosci 114:950-956, 2000.
61. deRegnier RA, Nelson CA, Thomas K, Wewerka S, Georgieff MK. Neurophysiologic evaluation of auditory recognition memory in healthy newborn infants and infants of diabetic mothers. J Pediatr 137:777-784, 2000.
62. Georgieff MK, Wobken JK, Welle J, Burdo JR, Connor JR. Identification and localization of divalent metal transporter-1 (DMT-1) in term human placenta. Placenta 21:799-804, 2000.
63. Rao R, Georgieff MK. Perinatal iron metabolism. Recent Res Dev Nutr 3:97-114, 2000.
64. Georgieff MK. Fetal and neonatal iron metabolism. Sem Neonat Nutr Metab 7:1-5, 2000.
65. Lindeke LL, Shell CD, Mills MM, Georgieff MK, Wrbsky PM. Impact of genetic potential and prematurity on growth outcomes. MCN 26:178-183, 2001.
66. Georgieff MK. Taking a rational approach to the use of infant formulas. Contemporary Pediatrics 18(8):112-130, 2001.
67. Mulrooney DA, Carpenter B, Georgieff MK, Angel C, Hunter D, Foker J, Steiner M. Hepatic mesenchymal hamartoma in a neonate: A case report and review of the literature. Am J Pediatr Hem/Onc 23:316-317, 2001.
68. Rao R, Georgieff MK. Neonatal iron nutrition. Semin Neonatol 6:425-435, 2001.
69. Curtis WJ, Lindeke L, Georgieff MK, Nelson CA. Neurobehavioural functioning in neonatal intensive care unit graduates in late childhood and early adolescence. Brain 125:1646-1659, 2002.
70. Siddappa AJM, Rao RB, Wobken JD, Leibold EA, Connor JR, Georgieff MK. Developmental changes in the expression of iron regulatory proteins and iron transport proteins in the perinatal rat brain. J Neurosci Res 68:761-775, 2002.
71. Premer DM, Goertz R, Georgieff MK, Mammel MC, Schwarzenberg SJ. Muscle proteolysis and weight loss in a neonatal rat model of sepsis. Inflammation 26:97-101, 2002.
72. deRegnier R-A, Wewerka S, Georgieff MK, Mattia F, Nelson CA. Influences of post-conceptional age and postnatal experience on the development of auditory recognition memory in the newborn infant. Dev Psychobiol 41:216-225, 2002.
73. Georgieff MK, Wewerka SW, Nelson CA, deRegnier R-A. Iron status at 9 months of infants with low iron stores at birth. J Pediatr 141:405-409, 2002.
74. Rao R, Georgieff MK. Perinatal aspects of iron metabolism. Acta Paediatr [Suppl] 438:124-129, 2002.
75. Siddappa AJM, Wobken JD, Leibold EA, Rao R, Connor JR, Georgieff MK. Iron deficiency alters iron regulatory protein and iron transport protein expression in the perinatal rat brain. Pediatr Res 57:800-807, 2003.
76. Tkac I, Rao R, Georgieff MK, Gruetter R. Developmental and regional changes in the neurochemical profile of the rat brain determined by in vivo 1H NMR spectroscopy. Magn Reson Med 50:24-30, 2003.
77. Nelson CA, Wewerka SS, Borscheid AJ, deRegnier R-A, Georgieff MK. Electrophysiologic evidence of impaired cross-modal recognition memory in 8-month-old infants of diabetic mothers. J Pediatr 142:575-582, 2003.
78. Stolarova M, Whitney H, Webb S, deRegneir RA, Georgieff MK, Nelson CA. Electrophysiologic brain responses of six-month-old low risk premature infants. Infancy 4:437-450, 2003.
79. Jorgenson LA, Wobken JD, Georgieff MK. Perinatal iron deficiency alters apical dendritic growth in hippocampal CA-1 pyramidal neurons. Dev Neurosci 25:412-420, 2003.
80. Whitney H, Georgieff MK. The effect of adverse intrauterine and newborn environments on cognitive development: The experience with diabetes during pregnancy and with premature delivery. Dev Psychopathol 15:991-1015, 2003.
81. Rao R., Tkac I, Townsend EL, Gruetter R, Georgieff MK. Perinatal iron deficiency alters the neurochemical profile of the developing rat hippocampus. J Nutr 133:3215-3221, 2003.
82. Davis EP, Townsend E, Gunnar M, Georgieff MK, Guiang SF, Cifuentes RF, Lussky RC. Effects of prenatal betamethasone exposure on regulation of stress physiology in healthy premature infants. Psychoneuroendocrinology 29:1028-1036 (2004).
83. Siddappa AM, Georgieff MK, Wewerka S, Worwa C, Nelson CA, deRegnier R-A. Auditory recognition memory in iron-deficient infants of diabetic mothers. Pediatric Research 55: 1034-1041; 2004.
84. Bradley J, Leibold EA, Harris ZL, Wobken J, Clarke S, Zumbrennen KB, Eisenstein R, Georgieff MK. The influence of gestational age and fetal iron status on iron regulatory protein activity and iron transporter protein expression in third trimester human placenta. Am J Physiol 287:R894-R901; 2004
85. Black LS, deRegnier RA, Georgieff MK, Nelson CA. Electrographic imaging of recognition memory processing in 34-38 week gestation intrautering growth restricted newborns. Experimental Neurology 190: S72-S83, 2004.
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88. Cheatham CL, Bauer PJ, Georgieff MK. Predicting individual differences in recall by infants born preterm and fullterm. Infancy (in press, 2006).
89. Georgieff MK, Innis S. Controversial nutrients in the perinatal period that potentially affect neurodevelopment: essential fatty acids and iron. Pediatr Res 57:99R-103R; 2005
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101. Rao R, Tkac I, Townsend EL, Ennis K, Gruetter R, Georgieff MK. Perinatal iron deficiency predisposes the developing rat hippocampus to greater injury from mild to moderate hypoxia-ischemia. J Cereb Blood Flow & Metab (2006):1-12; 2006.
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103. Siddappa AJ, Rao R, Long JD, Widness JA, Georgieff MK. The assessment of newborn iron stores at birth: A review of the literature and standards for ferritin concentrations. Neonatology, in press, 2007.
104. Ward KL, Tkac I, Jing Y, Felt B, Beard J, Connor J, Schallert T, Georgieff MK, Rao R. Gestational and lactational iron deficiency alters the developing striatal metabolome and associated behaviors in young rats. J. Nutrition, in press, 2007.
Book Chapters and Review Articles
1. Georgieff MK, Sasanow SR. Assessment of neonatal nutrition In Pereira GR, ed. Clinics in Perinatology. Philadelphia: W.B. Saunders, 1986; 13(1):73-90.
2. Stahl BE, Georgieff MK, Pereira GR. Fetal nutrition and growth. In Grand RJ, Sutphen JL, Dietz WH, Eds. Pediatric Nutrition: Theory and Practice. Boston: Butterworths, 1987; 221-238.
3. Georgieff MK, Pereira GR. Nutritional Assessment. In Fox WW, Polin RA, Eds. Fetal and Neonatal Physiology. W.B. Saunders, 1992; 277-284.
4. Georgieff MK. Nutritional deficiencies as developmental risk factors: Commentary on Politt and Gorman. In Nelson CA, ed. Threats to Optimal Development: Integrating Bio-psycho-social Risk Factors. Minnesota Symposia on Child Psychology Vol 27. Parsippany, NJ: Lawrence Erlbaum Assoc, 1994; 145-159.
5. Georgieff MK. Therapy of infants of diabetic mothers. In Burg FD, Ingelfinger JR, Wald ER, Polin RA, Eds. Current Pediatric Therapy 15. Philadelphia: W.B. Saunders, 1995; 793-803.
6. Wahlig TM, Georgieff MK. The effect of neonatal illness on nutritional requirements. In Pereira GR, Georgieff MK, Eds. Clinics in Perinatology. Philadelphia: W.B. Saunders, 1995; 22:77-96.
7. Guiang SF III, Georgieff MK. Fetal and Neonatal Iron Metabolism. In Fox WW, Polin RA, Eds. Fetal and Neonatal Physiology. Philadelphia: W.B. Saunders, 1997 (second edition).
8. Georgieff MK, Pereira GR. Nutritional Assessment. In Fox WW, Polin RA, Eds. Fetal and Neonatal Physiology. Philadelphia: W.B. Saunders, 1997 (second edition).
9. Georgieff MK. Nutrition. In Avery GB, MacDonald M, Fletcher MA, Eds. Neonatology: Pathophysiology and Management of the Newborn (fifth edition). Philadelphia: Lippincott & Co, 1998.
10. Premer D, Georgieff MK. Nutritional Needs of Ill Neonates. Neo Reviews, American Academy of Pediatrics, Elk Grove Village. 1999.
11. Rao R, Georgieff MK. Early Nutrition and Brain Development. Minnesota Symposium on Child Psychology, vol. 31. New Jersey: Erlbaum Assoc, 2000; pp 1-30.
12. Georgieff MK. Prematurity and Early Brain Development. In Early Experience and Childhood Development. National Academy of Sciences Position Statement. Washington, D.C.: National Academy of Sciences, 2000.
13. Georgieff MK, Rao R. The Role of Nutrition in Cognitive Development. In Handbook in Developmental Cognitive Neuroscience. Cambridge, MA: MIT Press, 2000; pp 491-504.
14. Georgieff MK. Iron Deficiency. In Kleinman R., Ed. Pediatric Nutrition Handbook. AAP Press; Elk Grove Village, IL; pp 299-312, 2003.
15. Georgieff MK. Hematologic Disorders in the Neonate: Iron Deficiency. In Polin RA, Spitzer AR, Eds. Fetal and Neonatal Secrets. Philadelphia: Hanley & Belfus, Inc. 2004.
16. Rao R, Georgieff MK. Microminerals. In Tsang R, Uauy R, Koletzko B, Zlotkin S, Eds. Nutritional Requirements of the Premature Infant Digipub: Cincinnati, OH ), 2005; pp 277-310.
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23. Fugelstad A, Rao R, Georgieff MK. The Role of Nutrition in Cognitive Development. In Handbook in Developmental Cognitive Neuroscience. (2nd Edition) Cambridge, MA: MIT Press, In press, 2006.
Books (editor)
1. Pereira GR, Georgieff MK. Neonatal/Perinatal Nutrition. Clinics in Perinatology. Volume 22:1. Philadelphia: W.B. Saunders, 1995.