Pharmacology of Drugs in Kidney Disease

I.   Program Content

1. Trainees must acquire knowledge and understanding of the following areas during the course of their training:

1. Principles of drug pharmacokinetics.

2. Renal handling of drugs and chemical.

3. Mechanisms of durg metabolism.

4. Drug prescribing in disease states and during dialysis.

5. Relevant drug-drug interactions.

6. Mechanisms of drug nephrotoxicity.

7. Management of drug-induced renal diseases.

8. Therapeutic drug monitoring.

9. Renal transplant immunosuppression.

II.   Patient Care Experience.

1. Trainees should also be familiar with, and preferably have experience in, the direct diagnosis and management of the following areas, in both an outpatient and inpatient setting:

1. Trainees must diagnose and manage patients with different drug-induced renal syndromes.

2. Trainees should be able to prescribe for and adjust drug dosage in patients with renal dysfunction.

3. Trainees should understand indications of therapeutic drug monitoring.

4. Trainees should be able to access drug and poison information.

5. Trainees should be familiar with common overdoses and the need for extracorporeal therapy.

6. Trainees should prescribe and manage immunosuppression for renal transplantation.