Peterson Lab

Please visit the Peterson Lab site here: Dr. Erik Peterson Lab Site

Assistant Professor, Division of Rheumatic and Autoimmune Diseases, Department of Medicine, University of Minnesota. Dr. Peterson joined the division in July, 2002. He is also a member of the interdisciplinary Cancer Center and the Center for Immunology. He is a an NIH-funded investigator studying the molecular mechanisms underlying leukocyte activation and the development of autoimmunity. He is a board-certified rheumatologist and is a key faculty member in the adult Rheumatology fellowship program.

Dr. Peterson has strong interests in the development and function of the immune cells that have been implicated in a number of autoimmune diseases. He is currently conducting research into the biological role of a novel adapter protein, PRAM-1, that he helped to isolate and identify. PRAM-1 is implicated in the pathogenesis of myeloid leukemia, and may play roles in myeloid signaling and development. Using genetic and biochemical approaches, the Peterson laboratory is investigating the mechanism whereby PRAM-1 regulates neutrophil integrin signaling and reactive oxygen species production. His previous work has already shown the critical importance of a related protein, ADAP, for T cell receptor mediated cell-cell and cell-matrix adhesion in T cells. Current experiments with ADAP-deficient mice are determining how ADAP regulates T cell development.

Email: peter899@umn.edu

Telephone, office 612-625-5634

Laboratory 612-625-0661