James V. Harmon, Jr, MD, PhD

Assistant Professor, Department of Surgery

James V. Harmon, Jr

Contact Info

harm0031@umn.edu

Office Phone 612-625-7911

Fax 612-626-0439

Mailing Address:
Surgical Critical Care
420 Delaware St SE, MMC 195
Minneapolis, MN 55455

Administrative Assistant Name
Colleen Powers

Administrative Phone
612-625-7129

Administrative Email
power202@umn.edu

Assistant Professor, Department of Surgery

Assistant Professor, Department of Integrative Biology and Physiology (IBP)

Medical Student and Surgery Resident Site Director, General and Vascular Surgery Service, UMMC

Clinical Co-Director, Critical Care for SimPORTAL


Critical Care Surgeon, General Surgeon


MD, Mayo Medical School, 1985

Residency, Massachusetts General Hospital (Pathology), 1986 - 1990;

Residency, University of Minnesota (Surgery), 1993 - 2000

Fellowship, University of Minnesota (Research), 1998;

Fellowship, University of Minnesota (Solid Organ Transplant), 2003;

Fellowship, University of Minnesota (Surgical Critical Care), 2007

PhD, University of Minnesota (Surgery), 2001

BS, University of Minnesota (Biology), 1981

University Laval, 1978;

Internship, Mary Imogene Basset Hospital, 1986;

Postgraduate Training, University of Minnesota (Gastrointestinal Endoscopy), 1997;

Postgraduate Training, University of Minnesota (Surgical Infectious Disease), 1998;

Naval School of Health Sciences, 2004

Summary

I serve as the Medical Student and Resident Site Director for General and Vascular Surgery at the University of Minnesota. My goal is to deliver clinical excellence, compassionate patient care, pioneering research, and to educate surgical leaders. 

Expertise

  • Acute and Critical Care Surgery
  • Islet Transplantation
  • General Surgery

Awards & Recognition

  • Mpls.St. Paul Magazine "Top Doctor", 2014-2015
  • Distinguished Teaching Award, Minnesota Medical Foundation, University of Minnesota, 2010, 2011, 2015
  • Henry Buchwald Award, Department of General Surgery, University of Minnesota, 1999
  • Phi Kappa Phi and Gamma Sigma Delta Honor Societies, University of Minnesota, 1981
  • Sigma Xi, Undergraduate Fellowship, University of Minnesota, 1979

Professional Associations

  • Society for the Surgery of the Alimentary Tract 
  • Society of American Gastrointestinal & Endoscopic Surgeons
  • Minneapolis Surgical Society 
  • American Association of Blood Banks 
  • Minnesota Surgical Society 
  • Society of Critical Care Medicine 
  • American College of Surgeons 
  • College of American Pathologists 
  • American Medical Association     

Research

Research Summary/Interests

  • Experimental Stem Cell Transplantation
  • Islet Allograft Transplantation
  • Advances in Hepatobiliary and Minimally Invasive Surgery
  • Patient Blood Transfusion Management
  • Surgical Education 

Research Funding Grants

  • Cirg - Raptiva Protocol for Islet Transplantation. Funding source: NIH. 5% Effort: Surgical Organ Procurement and Islet Transplantation. PI: Bernhard Hering, MD, 2008 – present
  • “Advancing Islet Transplants for Type 1 Diabetes Care” CIT-07 Islet Transplantation in Type 1 Diabetes. Funding source: NIH. 5% Effort: Surgical Organ Procurement and Islet Transplantation. PI: Bernhard Hering, MD, 2007-present
  •  “A double-blind, placebo-controlled study to determine the safety of recombinant human erythropoietin (rHuEPO) and whether rHuEPO can reduce postoperative transfusion requirements in subjects undergoing major orthopedic surgery.” Funding Source: R.W. Johnson Pharmaceutical Research Institute. (Completed) PI: James Vail Harmon, Jr., M.D. (MGH Center), 1991 – 1992

Publications

Peer Reviewed Publications

  • Harmon JV, Edwards WD. Venous valves in subclavian and internal jugular veins. Frequency, position and structure in 100 autopsy cases. Am J Cardiovasc Pathol 1986; 1(1):51-54. (Research execution, analysis, and wrote the manuscript)
  • Arbiser JL, Dzieczkowski JS, Harmon JV, Duncan LM. Leukocytoclastic vasculitis following staphylococcal protein A column immunoabsorption therapy. Arch Dermatol 1995 Jun; 131(6):707-709. (Case presentation, literature review, and assisted with the manuscript)
  • Cheek R, Harmon JV, Stowell C. Red cell alloimmunization after a bone allograft. Transfusion 1995; 35(6):507-9. (Case presentation, literature review, and wrote the manuscript)
  • Greussner R, Nakhleh R, Harmon J, Dunning M, Gruessner A. Donor-specific portal blood transfusion in intestinal transplantation: A prospective, preclinical large animal study. Transplantation 1998 Jul 27; 66(2):164-9. (Research execution, analysis, and assisted with the manuscript)
  • Humar A, Harmon J, Gruessner A, Kandaswamy R, Granger D, Zheng C, Drangstveit MB, Sutherland D, Gruessner R. Surgical complications requiring early relaparotomy after pancreas transplantation: comparison of the cyclosporine and FK 506 eras. Transplantation Proceedings 1999; 31(1-2):606-7. (Case series review, literature review, and assisted with the manuscript)
  • Kandaswamy R, Humar A, Gruessner AC, Harmon JV, Granger DK, Lynch S, Sutherland DE, Gruessner RW. Vascular graft thrombosis after pancreas transplantation: comparison of the FK 506 and cyclosporine eras. Transplant Proc. 1999 Feb-Mar: 31(1-2):602-3. (Case series review, literature review, and assisted with the manuscript)
  • Harmon JV, Gruessner AC, Nakhleh R, Zhang K, Gruessner RWG. Experimental short- term immunosuppression after bowel transplantation and donor-specific bone marrow infusion in a large animal model. Arch Surg 2001 Jul; 136(7):817-821. (Research execution, analysis, and wrote the manuscript)
  • Hering BJ, Kandaswamy R, Harmon JV, Ansite JD, Clemmings SM, Sakai T, Paraskevas S, Eckman PM, Sageshima J, Nakano M, Sawada T, Matsomoto I, Zhang HJ, Sutherland DE, Bluestone JA. Transplantation of cultured islets from two-layer preserved pancreas in type I diabetes with anti-CD3 antibody. Am J Transplant. 2004 Mar;4(3):390-401. (Research execution, analysis, and assisted with the manuscript)
  • Jie T, Harmon JV Jr, Gulbahce HE, Gruessner R. Intraductal papillary mucinous tumor of the native pancreas in a pancreas-kidney transplant recipient. Pancreas. 2004 May;28(4):446-9. (Case presentation, literature review, and wrote the manuscript)
  • Khwaja K, Asolati M, Harmon JV, Melancon JK, Dunn TB, Gillingham KJ, Kandaswamy R, Humar A, Gruessner RW, Payne WD, Najarian JS, Dunn, Sutherland DE, Matas AJ. Rapid discontinuation of prednisone in higher-risk kidney transplant recipients. Transplantation 2004 Nov 15;78(9):1397-9. (Case Series review, literature review, and assisted with the manuscript)
  • Khwaja K, Asolati M, Harmon J, Melancon JK, Dunn TB, Gillingham KJ, Kandaswamy R, Humar A, Gruessner R, Payne W, Najarian J, Dunn, Sutherland DE, Matas AJ. Outcome at 3 years with a prednisone-free maintenance regimen: a single-center experience with 349 kidney transplant recipients. American Journal of Transplantation. 2004 4(6):980-7. (Case series review, literature review, and assisted with the manuscript)
  • Mair DC, Eastland T, Rosen G, Colvin R, Harmon JV, Menser M, Carr R, Shrwany S Hemolysis during percutaneous mechanical thrombectomy can mimic a hemolytic transfusion reaction. Transfusion. 2005 Aug;45(8):1291-4. (Case presentation)
  • Klaas JP, Diller CL, Harmon JV, Skarda DE. Death caused by splenic artery aneurysm rupture during dobutamine-atropine stress echocardiography: case report and literature review. Echocardiography. 2009 Jan;26(1):93-5. (Case presentation, lit. review, and assisted in the manuscript)
  • A.N. Balamurugan, G. Loganathan, M. Bellin, J.J. Wilhelm, J. Harmon, S.M. Soltani, M. Tiwari, K.K. Papas, R.C. McCarthy, D.E. Sutherland, B.J. Hering. A new enzyme mixture to increase the yield and transplant rate of autologous and allogenic humnna islet products. In press Transplantation. TPA-2011-0742.R1

Non-Peer Reviewed Publications

  • Olds GR, Harmon JV. Case Records of the MGH. N Engl J Med 1990: 323:1614-24.(Case presentation, literature review, and wrote the manuscript)
  • Harmon JV, Osathanondh R, Holmes LB. Symmetric terminal transverse limb defects: Report of a twenty-week fetus. Teratology 1995 Apr; 51(4):237-242. (Research execution, analysis, and wrote the manuscript)
  • Iwanaga Y, Sutherland DE, Harmon JV, Papas KK. Pancreas preservation for pancreas and islet transplantation. Curr Opin in Organ Transplant. 2008 Apr;13(2):135-41. (Literature review and assisted with the manuscript)

Abstracts

  • Harmon JV, Osathanondh JR, Holmes LB. Absent phalanges, hypoplastic metacarpals/metatarsals and hydrops in a 20 week-gestation fetus. 29th Annual Meeting of the Teratology Society, June 3-8, 1989; Richmond Virginia, Teratology 1989; 39:457.
  • Harmon JV, Powelson J, Sachs D, Shopis JA, Cosimi AB. Blood component preparation for discordant liver xenotransplantation. 2nd International Congress on Xenotransplantation, September 26-30, 1993, Cambridge, England
  • Pins MR, Misiano DR, Misiano JP, Harmon JV, Garrett PE, Shopis JR, McDermott TJ, Stowell CP. Comparative evaluation of commercially available, FDA approved, human immunodeficiency virus type-1 (HIV-1) confirmatory assays using quality control and indeterminate sera. American Society of Clinical Pathologists Spring Meeting. April 9-14, 1994, Seattle, Washington.
  • Humar A, Harmon J, Gruessner A, Kandaswamy R, Granger D, Zhang Y, Drangstveit M, Sutherland D, Gruessner R. Surgical complications requiring early relaparotomy after pancreas transplantation: comparison of the FK and CsA era. 24th Annual Meeting of the American Society of Transplant Surgeons. May 13-15, 1998, Chicago, Illinois.
  • Kandaswamy R, Humar A, Gruessner A, Harmon J, Granger D, Lynch S, Sutherland D, Gruessner R. Vascular graft thrombosis after pancreas transplantation: Comparison of the FK and CsA era. 24th Annual Meeting of the American Society of Transplant Surgeons. May 13-15, 1998, Chicago, Illinois.
  • Humar A, Gruessner A, Kandaswamy R, Harmon J, Granger D, Lynch S, Sutherland D, Gruessner R. Simultaneous pancreas-kidney transplantation: living related donor vs. cadaver donor. 24th Annual Meeting of the American Society of Transplant Surgeons. May 13-15, 1998, Chicago, Illinois.
  • Humar A, Gruessner AC, Harmon, J, Kandaswamy R, Granger D, Dragstveits MB, Lynch S, Southerland DER Intraabdominal infections after pancreas transplantation: Recent improvements in incidents and outcomes. AST 18th Annual Meeting. Chicago, May 1999
  • Harmon JV, Jie T, Kirchhof N, Hakan MS, Eastlund DT, Eide CR, Hering BJ. Peripheral blood stem cell mobilization and collection in non-human primates. Presented at the 6th International Congress of the Cell Transplant Society, March 2-5, 2003, Atlanta, GA
  • Humar A, Harmon JV, Asolati M, Payne WD, Gruessner RWG, Sutherland DER, Kandaswamy R, Koushik RS, Kasiske BL, Gillingham KJ. Acute rejection (AR) episodes occurring in kidney transplant recipients on steroid-avoidance protocol – What are the consequences? Poster presentation at American Transplant Congress 2003, May 30-June 4, 2003, Washington DC. Amer J Transplantation 3(suppl 5):219, 2003.
  • Kandaswamy R, Humar A, Khwaja K, Asolati M, Harmon J, Gillingham K, Matas A. A prospective randomized study of Cyclosporine (CSA)/Cellcept (MMF) vs. tacrolimus (TAC)/sirolimus (SIR) with rapid discontinuation of prednisone (P). Presented at American Transplant Congress 2003, May 30-June 4, 2003, Washington DC. Amer J Transplantation 3(suppl 5):198, 2003.
  • Khwaja K, Asolati M, Harmon J, Gillingham K, Humar A, Kandaswamy R, Matas A. Successful rapid discontinuation of prednisone in high-risk kidney transplant recipients. Presented at American Transplant Congress 2003, May 30-June 4, 2003, Washington DC. Amer J Transplantation 3(suppl 5):352, 2003
  • Humar A, Harmon J, Asolati M, Kandaswamy R, Gruessner RWG, Payne WD, Sutherland DER, Matas AJ. Primary non-function (PNF) after kidney transplant –how common is it and what are the risk factors? Poster presentation at American Transplant Congress 2003, May 30-June 4, 2003, Washington DC. Amer J Transplantation 3(suppl 5):368: 2003.
  • Khwaja K, Asolati M, Harmon J, Gillingham, K, Humar A, Kandaswamy R, Matas A. 95% graft survival at 3 years posttransplant with steroid-free maintenance immunosuppression. Presented at American Transplant Congress 2003, May 30-June 4, 2003, Washington DC. Amer J Transplantation 3(suppl 5):440, 2003.
  • Jie T, Kumar D, Humar Atul, Harmon J, Asolati M, Matas A, Gilliingham KJ, Humar Abhinav. Mycobacterial infections occurring after kidney transplant. Poster presentation at American Transplant Congress 2003, May 30-June 4, 2003, Washington DC. Amer J Transplantation 3(suppl 5):512, 2003.
  • Harmon J, Matas AJ, Asolati M, Humar A, Gruessner RW, Sutherland DER, Dunn DL, Kandaswamy R. Right laparoscopic nephrectomies (LDNs) – Are there additional risks? Poster Presentation at American Transplant Congress 2003, May 30-June 4, 2003, Washington DC. Amer J Transplantation 3(suppl 5):491, 2003.
  • Humar A, Harmon J, Asolati M, Kandaswamy R, Payne WD, Gillingham, K, Matas A. Wound complications after kidney transplant – How much are the newer immunosuppression drugs playing a role? Presented at American Transplant Congress 2003, May 30-June 4, 2003, Washington DC. Amer J Transplantation 3(suppl 5):487, 2003.
  • Humar A, Asolati M, Harmon J, Kandaswamy R, Gruessner R, Gruessner A, Sutherland D. Causes of pancreas graft loss in 1500 pancreas transplant recipients: changing pattern over 25 years. Presented at American Transplant Congress 2003, May 30-June 4, 2003, Washington DC. Amer J Transplantation 3(suppl 5):487, 2003.
  • Kandaswamy R, Gillingham K, Harmon J, Asolati A. Decreased incidence of hypothermia and peritoneal irritation in laparoscopic donor nephrectomy using a filter-hydrator-heating device (Insuflow®). Presented at Society of American Gastrointestinal Endoscopic Surgeons (and International Pediatric Endosurgery Group) 2003 SAGES Scientific Session and Postgraduate Course, March 2003, Los Angeles, CA.
  • Hering BJ, Harmon JV, Jei T, Clemmings S, Wijkstrom M, Nakano M, Kirchof N, Blazar BR. Haploidentical 'megadose' peripheral blood stem cell transplants in Rhesus monkeys with minimal myelosuppression. American Transplant Congress, June 1, 2003
  • Kwaja K, Asolati M, Harmon J, Gillingham K, Humar A, Kandaswamy R, Matas A. Successful rapid discontinuation of prednisone in high-risk kidney transplant recipients. American Transplant Congress, June 2, 2003.
  • Melancon JK, Harmon JV, Dunn TB, Asolati M, Humar A, Matas A. Outcome of prednisone (P) minimization in an immunologically higher risk cohort - who has acute rejection (AR)? American Transplant Congress, May 14 - 19, 2004, Boston, MA
  • Humar A, Kandaswamy R, Harmon J, Melancon JK, Dunn DL, Tan M, Matas AJ. Prednisone (P)- free maintenance immunosuppression (IS) after kidney transplantation: 92% graft survival at 4 years. American Transplant Congress, May 14 - 19, 2004, Boston, MA
  • Humar A, Harmon JV, Dunn T, Melancon JK, Tan M, Kandaswamy R, Gruessner RWG, Matas A, Sutherland DER. Delayed pancreas graft function in SPK recipients - its impact on kidney graft function. American Transplant Congress, May 14 - 19, 2004, Boston, MA
  • Asolati M, Kim Y, Melancon JK, Dunn T, Tan M, Harmon JV, Matas A. C4d+ renal biopsies - treat the staining or the patient? American Transplant Congress, May 14 - 19, 2004, Boston, MA
  • Humar A. Kandaswamy R, Harmon JV, Melancon JK, Tan M, Dunn T, Gruessner RWG, Sutherland DER, Gruessner AC. Results with pancreas transplantation in recipients with a history of major lower extremity amputations. American Transplant Congress, May 14 - 19, 2004, Boston, MA
  • Hering B, Parkey J, Kandaswamy R, Jevne R, Snead D, Lervik B, Harmon J, Tanaka T, Papas K, Pakala P, and Sutherland D. Analysis of Long-Term Islet Allograft Function in Recipients with Type 1 Diabetes Given Depleting T-Cell Antibodies for Induction Immunosuppression. Xenotransplantation 14[5], 398. 2007.
  • Hering B, Parkey J, Kandaswamy R, Jevne R., Lervik, B, Harmon J, Pakala P, Papas K, and Sutherland D. Long-Term Survival of Human Islet Allografts in Type 1 Diabetes. Am.J.Transplant. 7[Supplement 2], 205. 2007.
  • Banton K, Harmon J, Acton R, Saltzman D, Hess D. Adapting massive transfusion protocols for the pediatric patient. Minnesota Surgical Society, Annual meeting. May 2, 2008.
  • Chipman JG, Schmitz CC, Riehsen T, Rezcallah A, Marquez S, Harmon J, Sahr C, AND Polly. Development and use of a surgical OSATS to assess a simulation curriculum for interns. American College of Surgeons Annual meeting, October 13- 16, 2008.
  • Zantek ND, Morgan SM, Harmon JV, Eubanks JA, Senn CK, Bowman RJ. Implementation of a Massive Transfusion Protocol at a University Medical Center. Submitted on May 6, 2009 for American Association of Blood Banks Annual Conference 2009.
  • Jacobs X, Harmon JV, Johnson JS. Monitored Anesthesia Care for Islet Allograft Transplantation. American Association of Anesthesiologists Oct. 16 – 20, 2010.
  • Mukesh Tiwari, Brian Flanagan, James Harmon, Josh Wilheim, Gopalakrishnan Loganathan, David E.R. Sutherland, Bernhard J. Hering and A. N. Balamurugan Factors determining the acceptance of deceased donor pancreases for human islet transplantation Submitted March 2011. Schulze Diabetes Institute, University of Minnesota.
  • AN Balamurugan, G Loganathan, M Bellin, JJ Wilhelm, J Harmon, SM Soltani, M Tiwari, KK Papas, RC McCarthy, DE Sutherland, BJ Hering. New enzyme mixture consistently achieves higher islet yield for human islet auto- and allo-transplantations Submitted March 2011. Schulze Diabetes Institute, University of Minnesota, and VitaCyte, Indianapolis, USA

Teaching

Teaching Areas

  • Surgery
  • Pathology

Courses

SURG 7500; Medical School Human Anatomy 6150; Surgical Anatomy

Clinical

Board Certifications

  • General Surgery
  • Surgical Critical Care

Clinical Interests

Acute Care Surgery; General surgery; Minimally Invasive Surgery; Transplant Surgery; Trauma Surgery; Surgical Critical Care