Apostolos P. Georgopoulos, MD, PhD

Professor, Department of Neuroscience

Apostolos P. Georgopoulos

Contact Info


Office Phone 612-725-2282

Office Address:
Brain Science Center VA Medical Center

Professor, Department of Neuroscience

Regents Professor of Neuroscience

McKnight Presidential Chair in Cognitive Neuroscience

Director and American Legion Brain Sciences Chair, Brain Sciences Center

Professor of Neuroscience, Neurology, and Psychiatry

Affiliate Faculty, Institute for Health Informatics (IHI)

Affiliate Faculty, Center for Cognitive Sciences

MD, University of Athens School of Medicine

Ph.D. degree in Physiology, University of Athens, Greece, 1969


Research Summary/Interests

Brain Mechanisms of Movement and Cognition; Functional Brain Biomarkers; Cortical Networks

There three major goals of our research: First, to elucidate the neural mechanisms underlying motor control and cognitive processing; second, to develop functional brain biomarkers for various brain diseases; and third, to understand the workings of developing cortical networks. For the first aim, we pursue experimental psychological studies, neurophysiological recordings, functional magnetic resonance imaging (MRI) at high fields (3, 4 and 7 Tesla), magnetoencephalography (MEG), and neural network modeling (using a supercomputer). For the second aim, we use MEG. And for the third aim, we record electrical activity from embryonic cortical cell cultures using multielectrode arrays.

  • Magnetoencephalography of brain function
  • Neural mechanisms of cognitive processes
  • Neurophysiology of motor control and cognition
  • Functional MRI of motor and cognitive processes


Christova, P & Georgopoulos, AP 2018, 'Invariant and heritable local cortical organization as revealed by fMRI' Journal of neurophysiology, vol. 120, no. 2, pp. 760-764. https://doi.org/10.1152/jn.00137.2018

Carpenter, A, Baud-Bovy, G, Georgopoulos, AP & Pellizzer, G 2018, 'Encoding of serial order in working memory: Neuronal activity in motor, premotor, and prefrontal cortex during a memory scanning task' Journal of Neuroscience, vol. 38, no. 21, pp. 4912-4933. https://doi.org/10.1523/JNEUROSCI.3294-17.2018

James, LM, Dolan, S, Leuthold, AC, Engdahl, B, Georgopoulos, A & Georgopoulos, AP 2018, 'The effects of human leukocyte antigen DRB1*13 and apolipoprotein E on age-related variability of synchronous neural interactions in healthy women' EBioMedicine, vol. 35, pp. 288-294. https://doi.org/10.1016/j.ebiom.2018.08.026

James, LM, Christova, P, Lewis, SM, Engdahl, B, Georgopoulos, A & Georgopoulos, AP 2018, 'Protective Effect of Human Leukocyte Antigen (HLA) Allele DRB1*13:02 on Age-Related Brain Gray Matter Volume Reduction in Healthy Women' EBioMedicine, vol. 29, pp. 31-37. https://doi.org/10.1016/j.ebiom.2018.02.005

Georgopoulos, AP & Georgopoulos, A 2017, 'The Beautiful Brain and the influence of Santiago Ramón y Cajal on medicine' JAMA - Journal of the American Medical Association, vol. 318, no. 6, pp. 502-504. https://doi.org/10.1001/jama.2017.9858

Georgopoulos, AP, James, LM, Carpenter, AF, Engdahl, BE, Leuthold, AC & Lewis, SM 2017, 'Gulf War illness (GWI) as a neuroimmune disease' Experimental Brain Research, vol. 235, no. 10, pp. 3217-3225. https://doi.org/10.1007/s00221-017-5050-0

Christova, P, James, LM, Engdahl, B, Lewis, SM, Carpenter, A & Georgopoulos, AP 2017, 'Subcortical brain atrophy in Gulf War Illness' Experimental Brain Research, vol. 235, no. 9, pp. 2777-2786. https://doi.org/10.1007/s00221-017-5010-8

James, LM, Engdahl, B & Georgopoulos, AP 2017, 'Apolipoprotein E: the resilience gene' Experimental Brain Research, vol. 235, no. 6, pp. 1853-1859. https://doi.org/10.1007/s00221-017-4941-4

James, LM, Christova, P, Engdahl, B, Lewis, SM, Carpenter, A & Georgopoulos, AP 2017, 'Human Leukocyte Antigen (HLA) and Gulf War Illness (GWI): HLA-DRB1*13:02 Spares Subcortical Atrophy in Gulf War Veterans' EBioMedicine, vol. 26, pp. 126-131. https://doi.org/10.1016/j.ebiom.2017.11.005

James, LM, Engdahl, B, Leuthold, AC & Georgopoulos, AP 2016, 'Brain Correlates of Human Leukocyte Antigen (HLA) Protection in Gulf War Illness (GWI)' EBioMedicine, vol. 13, pp. 72-79. https://doi.org/10.1016/j.ebiom.2016.10.019