Jizhen Lin, MD

Associate Professor, Department of Otolaryngology, Head and Neck Surgery

Jizhen Lin

Contact Info

linxx004@umn.edu

Lab Phone 612-624-5259

Office Address:
Phillips-Wangensteen Building
Room 8-310
420 Delaware Street SE
Minneapolis, MN55455
612-625-5994

Lab Address:
Lions Research Building
Room 270
2001 6th Street SE
Minneapolis, MN 55455

Administrative Phone
612-626-9885

Fujian Medical College

Union Hospital

Clinical - Union Hospital

Research - University of Minnesota

Research

Research Summary/Interests

  • Cancer immunotherapy research with a focus on development of antibody drugs
  • Identification and visualization of cancer biomarkers in animal models with antibody probes under PET/CT and/or MRI
  • Cancer cell therapy with CAR-T and TCR-T technologies 

Publications

  • Lin XY, Tao Z, Xiong JN, Zhang Q, Jiang P, Li XF, Lin SC, Xu QQ, Weng HJ, Lai HC, Lin JX, Cheng MM, Tian XL, Xu YL, Fang SB, Jin R, Chen ZW, Yang JB, Morton L, Yueh B, Lin J. Combined a-programmed death-1 monoclonal antibody blockade and fractionated radiation therapy reduces tumor growth in mouse EL4 lymphoma. Cancer Biology & Therapy, 5:666-679, 2019
  • Fu XM, Zhu XY, Qin FJ, Zhang Y, Lin J, Ding YC, Yang ZH, Shang YM, Wang L, Zhang QX, Gao QL. Linc00210 drives Wnt/b-catenin signaling activation and liver tumor progression through CTNNBIP1-dependent manner. Molecular Cancer,17:73, 2018
  • Lai J, Cai Q? Biel MA, Wang C, Hu XH, Wang SY, Lin J. Id1 and NF-kB promote the generation of CD133+ and BMI-1+ keratinocytes and the growth of xenograft tumors in mice. International journal of Oncology, 44:1481-1489, 2014
  • Sun W, Guo MM, Han P, Lin J, Liang FY, Tan GM, Li HB, Zeng MS, Huang XM. Id-1 and the p65 subunit of NF-?B promote migration of nasopharyngeal carcinoma cells and are correlated with poor prognosis. Carcinogenesis 2012; 33:810-817.
  • Lin J, Guan Z, Wang C, Feng L, Zheng Y, Granados EC, Bearth E, Peng J, Gaffney P, Ondrey FG. Inhibitor of differentiation 1 contributes to head and neck squamous cell carcinoma survival via the NF-kB/surviving and phosphainositide 3-kinase/Akt signaling pathways. Clin Cancer Res. 2010; 16:77-87.