Timothy Schacker
,
Credentials
MD
Bio
Administrator Info
Name: Craig Olson
Phone: 612-626-6577
Email: olso7966@umn.edu
Mail: 420 Delaware ST SE
MMC 250
Campus Delivery Code 8250A
Minneapolis, MN 55455
Summary
Timothy Schacker, M.D. is a professor of Medicine and Director of the Program in HIV Medicine at the University of Minnesota. He joined the faculty in 1996. Dr. Schacker received his M.D. from the University of Minnesota in 1986 and completed a residency in Internal Medicine at the Oregon Health Sciences University and Infectious Disease Fellowship at the University of Washington in 1993. He then joined the faculty of the University of Minnesota.Dr. Schacker is interested in how HIV causes immune suppression and why antiretrovirals do not fully restore immunity. His group focuses on inflammatory damage in lymphatic tissues; the principal site of HIV infection, that results in fibrosis of the lymphatic structures required to maintain a normal population of CD4 cells. They are testing novel therapies to prevent and/or reverse this process and slow T cell depletion in HIV and improve their reconstitution when antiretroviral is begun. He is also the principal investigator of a federally funded program of projects designed to determine barriers to HIV eradication. In addition, Dr. Schacker has established a collaboration with the Joint Clinical Research Center in Kampala, Uganda to study how constant exposure to common infections like tuberculosis, malaria, and helminthic infections affect rates of HIV transmission and progression.
Research Summary
IL-15 to Deplete HIV Reservoirs and Improve Immune Responses; Antifibrotic Therapy to Improve Immune Reconstitution in HIV
Research Funding Grants
- Predictors of Time to Viremia with an Analytic Treatment Interruption, amfAR, 109496-60-RGRL, Principal Investigator.
- Reservoir Dynamics in Patients Treated in Very Early Acute HIV Infection, NIH, R01 AI125127, Principal Investigator.
- Reversing Tissue Fibrosis to Improve Immune Reconstruction in HIV, NIH, U01AI105872, Principal Investigator.
- Antifibrotic Therapy to Improve Immune Reconstitution in HIV, NIH, R01 AI093319-01A1, Principal Investigator.
- IL-15 to Deplete HIV Reservoirs and Improve Immune Responses, Altor Bioscience, ALT-803, Principal Investigator.
Clinical Summary
HIV