$2.6 million NIH grant boosts U’s heart attack research

A University of Minnesota research team was awarded $2.6 million by the National Institutes of Health (NIH) to investigate new treatments for heart attacks. The research will focus on myocardial ischemia and reperfusion injury, which account for more than 300,000 deaths each year in the United States.

The research team will work on developing new strategies to prevent the second wave of heart damage that can occur when blocked arteries are re-opened to restore blood flow. Investigating the advanced generation of synthetic “molecular Band-Aids,” the medical researchers plan to develop treatments to protect cardiac tissue during reperfusion.

Experts on the U research team cover a variety of disciplines, including chemical engineering and material sciences, clinical cardiology, and biology and physiology.

“This grant offers a wonderful example of tapping into the richness of scholarship and expertise at the University of Minnesota as directed toward a significant biomedical research problem,” says the grant’s principal investigator, Joseph Metzger, Ph.D., who leads the Medical School’s Department of Integrative Biology and Physiology and holds the Maurice B. Visscher Chair in Physiology.

Published on May 18, 2015