Research

pharmacology research

Research is a critical component to the Department of Pharmacology Mission. The Department includes over 50 program faculty, representing 15 Departments and 5 Colleges within the University of Minnesota system, each of whom contributes high-impact research in one or more of four broad disciplinary areas: cancer and infectious diseases, neuropharmacology and neurodegeneration, cell signaling, and drug addiction and toxicology. Within these fields, our faculty are responsible for the development of novel drugs, vaccines, and therapeutic techniques that have led to better understandings of the diseases and disorders they seek to treat.

Highlighted Publications

McCall NM, Fernandez de Velasco EM, Wickman K. GIRK channel activity in dopamine neurons of the ventral tegmental area bi-directionally regulates behavioral sensitivity to cocaine. J Neurosci. 2019 Mar 5: pii: 3101-18.

Edmund AB, Walseth TF, Levinson NM, Potter LR. The pseudokinase domains of guanylyl cyclase-A and -B allosterically increase the affinity of their catalytic domains for substrate. Sci Signal. 2019 Jan 29; 12(566): pii: eaau5378.

Stabile LP, Farooqui M, Kanterewicz B, Abberbock S, Kurland BF, Diergaarde B, Siegfried JM. Preclinical Evidence for Combined Use of Aromatase Inhibitors and NSAIDs as Preventive Agents of Tobacco-Induced Lung Cancer. J Thorac Oncol. 2018 Mar; 13(3): 399-412.

Livingston JA, Wang WL, Tsai JW, Lazar AJ, Leung CH, Lin H, Advani S, Daw N, Santiago-O'Farrill J, Hollomon M, Gordon NB, Kleinerman ES. Analysis of HSP27 and the Autophagy Marker LC3B+ Puncta Following Preoperative Chemotherapy Identifies High-Risk Osteosarcoma Patients. Mol Cancer Ther. 2018 Jun; 17(6):1315-1323.

Graves SM and Surmeier, DJ. Delayed Spine Pruning of Direct Pathway Spiny Projection Neurons in a Mouse Model of Parkinson’s Disease. Front Cell Neuro. 2019 Feb 12; 13: 1-6.

Delgado JL, Hsieh CM, Chan, NL, Hiasa H. Topoisomerases as anticancer targets. Biochem J. 2018 Jan 23; 475(2): 373-398.

Park SW, Persaud SD, Ogokeh S, Meyers TA, Townsend D, Wei LN. CRABP1 protects the heart from isoproterenol-induced acute and chronic remodeling. J Endocrinol. 2018 Mar; 236(3): 151-165.

RESEARCH ETHICS AT THE UNIVERSITY OF MINNESOTA

We are committed to protecting research participants, upholding ethical standards, and improving our practice at every step of our work.

Lab Safety

Contact for lab safety questions
Dr. Dan Romero
612-624-8997 (office)
romero@umn.edu

Pharmacology Lab Safety Plan


Emergency contacts for Nils Hasselmo Hall (NHH) & Jackson Hall

During business hours

Information Desk (8am - 4pm Monday - Friday):
612-626-0911
RBMSNHH@umn.edu

Sara Roberts
612-625-9491(office)

RBMS on-call phone
764-760-4794

After business hours, weekends, and urgent needs

RBMS on-call phone:
764-760-4794

Cheryl Miller:
612-625-5905 (office)
651-769-4664 (cell)


Emergency contact for Moos Tower

After business hours

612-624-3357 (Emergencies)
612-6274-2900 (Non-Emergencies)