Elizabeth Lusczek
,
Credentials
PhD

Associate Professor, Basic and Translational Research
Biography

Bio

Dr. Lusczek is an associate professor in the Department of Surgery with over 50 peer reviewed publications in physics and biomedical research. Her background in physics and mathematics drives her data science approach to translational research.

Research Summary

Dr. Lusczek’s primary interest is in precision medicine. Her expertise is in metabolomics and biomarker identification in the context of severe injury and critical illness.

Education

PhD, University of Minnesota
Major: Biophysical Sciences and Medical Physics
MS, University of Minnesota
Major: Physics
BS, Truman State University
Major: Physics/Mathematics

Fellowships, Residencies, and Visiting Engagements

NHLBI PRIDE Institute Sleep and Behavioral Medicine,
Postdoctoral Researcher,
University of Minnesota
Santa Fe Institute Complex Systems Summer School,

Honors and Recognition

Best Scientific Presentation for "Shock: Weathering the Storm", Midwest Regional Burn Conference
2018
Second Place: Basic Science Poster, University of Minnesota Department of Surgery Research Day
2013
Winifred H Wetzel Summer Research Fellowship
2006
Outstanding TA, University of Minnesota School of Physics and Astronomy
2005
Norton Scholar's Prize, Runner-Up, W.W Norton Publishing Company
2001
General Honors in the Arts and Sciences, Truman State University
2001
Dr. Robert Peavler Memorial Scholarship, Truman State University
1999

Professional Memberships

American Pancreas Association
Society for Complex Acute Illness, Member, Board of Directors
Shock Society
Society for Complex Acute Illness
Society of Critical Care Medicine
Selected Presentations

Selected Presentations

Lusczek, E. R. "Characterizing Critical Illness with Mass Spectrometry-based Metabolomics", MSI Bioinformatics group weekly seminar, November 07, 2018.
Lusczek, E. R. "Shock: Weathering the Storm", Midwest Regional Burn Conference, Bloomington, Minnesota, October 11, 2018.
Lusczek, E. R. "Modeling the Metabolic Response to Acute Illness", 16th International Conference on Complex Acute Illness, Milan, Italy. July 27, 2017.
Lusczek, E. R. "Metabolomics shows significant disruptions to metabolism after porcine burn injury", 16th International Conference on Complex Acute Illness, Milan, Italy. July 27, 2017.
Lusczek, E. R., Cornelissen, G., Goswami, U., Beilman, G. "Circadian Rhythms are Blunted in Critically Ill Patients", 40th Annual Conference on Shock, June 01, 2017.
Lusczek, E. R. "Circadian Rhythm Desynchronization in ICU Patients", Halberg Mini-Symposium, Minneapolis, Minnesota, May 19, 2017.
Lusczek, E. R., Myers, C., Popovsky, K., Beilman, G., Sawyer, R. "Aging and the Metabolic Response to Trauma", Symposium on Stress, Metabolism, and Aging, May 01, 2017.
Fortis, S., Lusczek, E. R., Weinert, C., Beilman, G. "Metabolomics in COPD Acute Respiratory Failure Requiring Noninvasive Positive Pressure Ventilation", CHEST, October 01, 2016.
Lusczek, E. R., Popovsky, K., Beilman, G., Sawyer, R. "The Elderly Metabolic Response to Trauma Differs from that of Adults", 39th Annual Conference on Shock, June 01, 2016.
Ennis, K., Lusczek, E. R., Rao, R. "Concurrent Metabolomic Changes in Plasma and the Brain During Acute Hypoglycemia in Young Rats", Midwest Society for Pediatric Research, October 01, 2015.
Lusczek, E. R. "Correlation and cluster analysis of clinical and metabolomics data in combat-related trauma", 14th International Conference on Complex Acute Illness, Cologne, Germany. September 27, 2015.
Lusczek, E. R. "Metabolic Markers of Injury and Mortality in Combat-Related Trauma", 2015 University of Minnesota Department of Surgery Research Day, Minneapolis, Minnesota, June 16, 2015.
Lusczek, E. R., Dubick, M., Beilman, G. "Metabolic Markers of Injury and Mortality in Combat-Related Trauma", 38th Annual Conference on Shock, Denver, Colorado, June 01, 2015.
Wolf, A., Witowski, N., Lusczek, E. R., Determan, C., Ostrowski, B., Beilman, G. "Pre-Injury Metabolic State Predicts Mortality in Porcine Hemorrhagic Shock and Polytrauma", 38th Annual Conference on Shock, Denver, Colorado, June 01, 2015.
Lusczek, E. R., Colling, K., Glover, J., Conwell, D., Freeman, M., Beilman, G. "NMR-Based Serum and Urine Metabolomics of ERCP-Induced Pancreatitis", American Pancreatic Association, Kona, Hawaii, November 01, 2014.
Lusczek, E. R., Vincent, T., Kulkarni, V., Mulier, K., Beilman, G. "Carbohydrate Pre-feeding Affects the Metabolic Response to Polytrauma, Hemorrhagic Shock, and Resuscitation In Serum Metabolic Networks", International Conference on Complex Acute Illness, Budapest, Hungary. August 01, 2013.
Determan Jr, C., Lusczek, E. R., Witowski, N., Pokorney, K., Mulier, K., Beilman, G. "Fed State changes Metabolic Response to Hemorrhagic Shock in Liver", 36th Annual Conference on Shock, San Diego, California, June 04, 2013.
Lusczek, E. R., Witowski, N., Determan Jr, C., Pokorney, K., Mulier, K., Beilman, G. "Two-Compartment Metabolic Networks in Porcine Hemorrhagic Shock and Injury Demonstrate BCAA Metabolism and Utilization", 36th Annual Conference on Shock, San Diego, California, June 01, 2013.
Pokorney, K., Lexcen, D., Lusczek, E. R., e. "Sensitive dependence on initial conditions: metabolism in porcine hemorrhagic shock", Journal of the American College of Surgeons [217.3 (2013): S55-S56], January 01, 2013.
Iyegha, U., Witowski, N., Lexcen, D., Mulier, K., Asghar, J., Lusczek, E. R., Beilman, G. "Does the fed state impact outcome in polytrauma and hemorrhagic shock?", The 67th Annual Sessions of the Owen H. Wangensteen Forum on Fundamental Surgical Problems, The American College of Surgeons 98th Annual Clinical Congress, Chicago, Illinois, October 04, 2012.
Lusczek, E. R., Lexcen, D., Witowski, N., Mulier, K., Beilman, G. "Behavior of scale-invariant metabolic networks during hemorrhagic shock", 71st Annual Meeting of The American Association for the Surgery of Trauma, Kauai, Hawaii, September 01, 2012.
Lusczek, E. R., Lexcen, D., Witowski, N., Mulier, K., Beilman, G. "Behavior of muscle scale-invariant metabolic networks during trauma and hemorrhagic shock", Military Health System Research Symposium, Fort Lauderdale, Florida, August 01, 2012.
Lusczek, E. R., Lexcen, D., Witowski, N., Mulier, K., Beilman, G. "Scale-free metabolic networks in a porcine model of trauma and hemorrhagic shock", International Conference on Complexity in Acute Illness, Ottawa, Ontario, August 01, 2012.
Witowski, N., Lexcen, D., Lusczek, E. R., Mulier, K., Iyegha, P., Asghar, J., Beilman, G. "Fed Status Alters the Muscle Metabolomic Response to Hemorrhagic Shock and Polytrauma", Military Health System Research Symposium, Miami, Florida, August 01, 2012.
Lexcen, D., Lusczek, E. R., Witowski, N., Asghar, J., Iyegha, P., Determan, C., Mulier, K., Beilman, G. "Liver and Muscle Metabolomics Identifies Biomarkers of Mortality in a Porcine Model of Polytrauma and Hemorrhagic Shock", Military Health System Research Symposium, Miami, Florida, August 01, 2012.
Lexcen, D., Lusczek, E. R., Witsowski, N., Ashgar, J., Iyegha, P., Mulier, K., Beilman, G. "Serum metabolomic Analysis of the Effects of glucose Pre-feed on Metabolism in a Porcine Model of Polytrauma and Hemorrhagic Shock", 35th Annual Conference on Shock, Miami Beach , Florida, June 09, 2012.
Lusczek, E. R., Lexcen, D., Witowski, N., Mulier, K., Beilman, G. "Scale-free urinary metabolic network analysis in trauma, hemorrhagic shock, and resuscitation", 35th Annual Conference on Shock, Miami Beach, Florida, June 09, 2012.
Iyegha, U., Mulier, K., Asghar, J., Witowski, N., Lusczek, E. R., Lexcen, D., Beilman, G. "Does the fed state impact outcome in hemorrhagic shock?", Region V Trauma Resident Paper Competition, Chicago, Illinois, November 09, 2011.
Lusczek, E. R., Paulo, J., Saltzman, J., Banks, P., Conwell, D., Beilman, G. "Urinary 1H-NMR Metabolics Discriminates Patients with Acute and Chronic Pancreatitis from Healthy Controls", American Pancreatic Association, Chicago, Illinois, November 01, 2011.
Iyegha, U., Mulier, K., Asghar, J., Witowski, N., Lusczek, E. R., Lexcen, D., Beilman, G. "Does the fed state impact outcome in hemorrhagic shock?", Minnesota Trauma Resident Paper Competition (Winner, Basic Science Category), Minnesota Surgical Society Meeting, St. Paul, Minnesota, September 30, 2011.
Lusczek, E. R., Lexcen, D., Witowski, N., Mulier, K., Beilman, G. "Differential Metabolic Response to Hemorrhagic Shock with Polytrauma Based on Fed State", Advanced Technology Applications for Combat Casualty Care, Fort Lauderdale, Florida, August 01, 2011.
Lusczek, E. R., Nelson, T., Lexcen, D., Witowski, N., Mulier, K., Chipman, J., Beilman, G. "Urine metabolomics identify energy alterations in porcine hemorrhagic shock", 34th Annual Conference on Shock, Norfolk, Virginia, June 01, 2011.
Lexcen, D., Greenberg, J., Lusczek, E. R., Witowski, N., Mulier, K., Beilman, G. "Physiologic parameters correlate to metabolomic markers in a porcine model of hemorrhagic shock", Advanced Technology Applications for Combat Casualty Care (ATACCC) 2010 Conference, St. Pete Beach, Florida, August 15, 2010.
Lusczek, E. R., Lexcen, D., Witowski, N., Greenberg, J., Mulier, K., Chipman, J., Beilman, G. "Biofluid analysis of hemorrhagic shock using metabolomics", Advanced Technology Applications for Combat Casualty Care (ATACCC) 2010 Conference, St. Pete Beach, Florida, August 15, 2010.
Lexcen, D., Greenberg, J., Lusczek, E. R., Witowski, N., Mulier, K., Beilman, G. "Physiologic parameters correlate to metabolomic markers in a porcine model of hemorrhagic shock", 33rd Annual Conference on Shock, Portland, Oregon, June 01, 2010.
Lusczek, E. R., Lexcen, D., Witowski, N., Mulier, K., Beilman, G. "Biofluid correlations in hemorrhagic shock", 33rd Annual Conference on Shock, Portland, Oregon, June 01, 2010.
Lusczek, E. R., Nelson, T., Lexcen, D., Witowski, N., Mulier, K., Beilman, G. "Urine normalization to account for dilution in a hemorrhagic shock model", 6th Annual Metabolomics Society Meeting, Amsterdam, Netherlands. June 01, 2010.
Lexcen, D., Chipman, J., Witowski, N., Lusczek, E. R., Mulier, K., Beilman, G. "Serum Metabolomic Biomarkers in Hypothermic and Normothermic Models of Hemorrhagic Shock Associated with Increased Mortality", LifeScience Alley Conference, Minneapolis, Minnesota, December 01, 2009.
Lusczek, E. R., Witowski, N., Mulier, K., Ostrowski, B., Chipman, J., Beilman, G. "Urine metabolomic analysis identifies biomarkers in a porcine model of hemorrhagic shock and resuscitation", 68th Annual Meeting of The American Association for the Surgery of Trauma, Pittsburgh, Pennsylvania, October 01, 2009.
Lusczek, E. R., Witowski, N., Lexcen, D., Mulier, K., Ostrowski, B., Chipman, J., Beilman, G. "Urinary niacinamide and 1-methylnicotinamide levels are elevated in injury: A metabolomic analysis", 5th Annual Metabolomics Society Meeting, Edmonton, Alberta, August 30, 2009.
Lusczek, E. R., Witowski, N., Mulier, K., Ostrowski, B., Chipman, J., Beilman, G. "Analysis of the urine metabolome identifies biomarkers in a porcine model of hemorrhagic shock", Advanced Technology Applications for Combat Casualty Care, St. Petersburg, Florida, August 01, 2009.
Witowski, N., Lusczek, E. R., Ostrowski, B., Blondet, J., Beilman, G. "Urine metabolic analysis identifies biomarkers in a porcine model of hemorrhagic shock and resuscitation", ATACCC, St. Petersburg Beach, Florida, August 01, 2008.
Scribner, D., Lusczek, E. R., Witowski, N., Beilman, G. "Liver metabolic changes identify active biochemical pathways in a porcine model of hemorrhagic shock", ATACCC, St. Petersburg Beach, Florida, August 01, 2008.
DuVernois, M., Barwick, S., Beatty, J., Besson, D., Binns, W., Cai, B., Clem, J., Connolly, A., Dowkontt, P., Evanson, P., Goldstein, D., Gorham, P., Herbert, C., Israel, M., Learned, J., Liewer, K., Link, J., Lusczek, E., Matsuno, S., Miocinovic, P., Nam, J., Naudet, C., Nichol, R., Palladino, K., Rosen, M., Saltzberg, D., Seckel, D., Silverstri, A., Stokes, B., Varner, G., Williams, D., Wu, F. "Radio Detection of UHE Neutrinos with the Antarctic Impulsive Transient Antenna (ANITA) Experiment: Data and Analysis", International Cosmic Ray Conference , Pune, India. August 01, 2005.
Lusczek, E. R. "Radio Emission in Air Showers and Dense Media", 29th International Cosmic Ray Conference, Pune, India. August 01, 2005.
Contact

Contact

Address

Moos Tower 11-208
515 Delaware St SE
Minneapolis, MN 55455

Administrative Contact

Kelli Tourand |  612-624-4581 | toura018@umn.edu