Grand Rounds Archive

Expand all

2023

January 11

Elena Frye Naharro    
Co Chief Resident    
Department of Laboratory Medicine and Pathology    
University of Minnesota Medical School 

"Navigating the new classification systems in hematopathology: Mature B cell lymphomas" 

  • Discuss the formation of the International Consensus Classification (ICC)

  • List the new entities within the ICC and the WHO 5th edition as it relates to mature B cell lymphomas

  • Identify and assess the differences in classification between the WHO 4th revised edition, WHO 5th edition, and ICC

January 18

Stefani Thomas, PhD
Assistant Professor   
Laboratory Medicine and Pathology   
University of Minnesota Medical School   
Minneapolis, Minnesota   

"Targeted mass spectrometry assays for serum protein high-grade serous ovarian cancer diagnostic biomarkers"

January 24

Christopher Tignanelli, MD   
Institute for Health Informatics   
Office of Academic Clinic Affairs   
University of Minnesota Medical School   
Minneapolis, Minnesota
Faculty host:  Leo Furcht, MD

"The Minnesota Learning Health System: Data to Knowledge, Knowledge to Performance, Performance to Data"

February 1

Andrew Stone, MD, PhD   
PGY4   
Laboratory Medicine and Pathology   
University of Minnesota Medical School   
Minneapolis, Minnesota

 “Rule Out MPN: Evaluation of molecular testing patterns for suspected myeloproliferative neoplasms"

February 8

Arun Rishi, PhD   
Professor   
Department of Oncology   
Department of Internal Medicine   
Wayne State University School of Medicine   
Wayne State University   
Detroit, Michigan
Faculty hosts:  Drs. Khalil Ahmed and Janeen Trembley

"CARP-1/CCAR1: A Master Regulator of Cell growth & Survival Signaling"

February 15

Meghan Delaney, DO, MPH   
Chief, Division of Pathology and Lab Medicine   
Director, Transfusion Medicine   
Professor of Pathology and Pediatrics   
George Washington University   
Washington, D.C.
Faculty host:  Dr. Claudia Cohn

"Access to safe blood transfusion in low and middle income nations: From 'big data' to mosquitos”

February 22

Hamid Tizhoosh, PhD   
Professor of Biomedical Information, Artificial Intelligence   
and Informatics   
Mayo Clinic   
Rochester, Minnesota   
Facultyost:  Dr. Alessio Giubellino

"Mayo Atlas - Going after Variability"

 

March 1

Yan Zhou, MD, PhD   
Co-Chief Resident   
Laboratory Medicine and Pathology   
University of Minnesota Medical School   
Minneapolis, Minnesota

"An approach to pediatric primary hepatocellular malignancies: Hepatoblastoma vs. hepatocellular carcinoma"

March 8

Elizabeth Wellberg, BS, PhD   
Assistant Professor   
Department of Pathology   
Harold Hamm Diabetes Center   
Stephenson Cancer Center   
College of Medicine   
The University of Oklahoma   
Oklahoma City, Oklahoma   

"FGFR/ER-signaling in the breast tumor environment links weight gain and endocrine-therapy resistance in a preclinical model of obesity"

March 15

Sanjay Patel, MD, MSc, MPH   
Assistant Professor   
Division of Hematopathology   
Weill Cornell/New York Presbyterian Hospital   
Weill Cornell Medicine   
New York, New York
Faculty Host:  Dr. Bartosz Grzywacz

“Spatial mapping of human hematopoiesis at single-cell resolution reveals topographic remodeling associated with aging”

March 22

Soheil Meshinchi, MD, Ph.D.
Professor, Department of Pediatrics   
University of Washington School of Medicine  
Fred Hutchinson Cancer Research Center  
Seattle, Washington
Faculty host:  Dr. Betsy Hirsch 

"AML-Restricted : Discovery and directed immunotherapeutic development"

March 29

Christopher Zarbock, MD 
Laboratory Medicine & Pathology PGY-3   
University of Minnesota Medical School   
Minneapolis, Minnesota
Faculty host:  Dr. Michelle Stoffel

"Artificial intelligence and pathology"

Objectives:

  1. Explain the basic tenets underlying machine learning

  2. Describe 2 applications of machine learning within pathology

  3. Outline major benefits but also important limitations of machine learning

April 5

Tiffany Seagroves, MBA, PhD   
Professor, Department of Pathology   
College of Medicine - Memphis    
University of Tennessee Health Sciences    
Memphis, Tennessee
Faculty host:  Dr. James McCarthy 

“Targeting metastasis in triple-negative breast cancer"

April 12

Meghan Driscoll, PhD   
Assistant Professor  
Molecular Pharmacology and Therapeutics   
Bioinformatics and Computational Biology    
Department of Pharmacology   
University of Minnesota Medical School    
Minneapolis, Minnesota
Faculty host:  Dr. Michael Greenwood

"Digging tunnels, shaping signaling, and other functions of cellular morphology"

April 19

Pawel Mroz, MD, PhD   
Assistant Professor   
Department of Laboratory Medicine and Pathology   
University of Minnesota Medical School   
Minneapolis, Minnesota

"Implementation of pharmacogenomic testing program at MHealth Fairview"

April 26

Vanessa Dayton, MD   
Adjunct Associate Professor   
Laboratory Medicine and Pathology   
University of Minnesota Medical School

"Diagnosing T-large granular lymphocytic leukemia in Vietnam: What WHO-HAEM5 isn’t telling us about T-LGLL in Asians (…yet)"

May 3

Eyal Gottlieb, PhD   
Professor   
Department of Cancer Research   
Vice President for Research   
MD Anderson Cancer Center   
University of Texas   
Houston, Texas
Faculty host:  Dr. Ameeta Kelekar

“Genetically- and environmentally-induced metabolic vulnerabilities of cancer”

May 10

Kevin Lin, BS   
Bioinformatics and Computational Biology   
MD/PhD Candidate   
Myers/Bielinsky Lab   
University of Minnesota Medical School   
Minneapolis, Minnesota   
Faculty host:  Dr. Andrew Nelson

“Scalable chemical screen platform for predicting drug mode of action”

May 17

Petros Giannikopoulos, MD   
Director, IGI Clinical Laboratory   
University of California, Berkeley   
Berkeley, California   
Faculty host:  Dr. Sophia Yohe

"The Role of Pathology in the Era of CRISPR-based Genomic Therapies"

May 24

Gabrielle N Winston McPherson, PhD   
Associate Director of Chemistry   
Henry Ford Hospital   
Detroit, Michigan   
DEI Lecture   
Faculty hosts:  Drs. Amy Karger and Deborah Powell

"Transgender Care, in and beyond the lab"   

 

September 13 

Danni Li, PhD 
Associate Professor  
Division of Clinical Chemistry  
Department of Laboratory Medicine and Pathology  
University of Minnesota Medical School  
Minneapolis, Minnesota 

"A blood-based approach to Alzheimer’s disease:  Think outside the box (brain)"


September 20

Srikar Chamala, PhD 
Director, Center for Pathology Informatics and Data Science 
Associate Professor, Clinical Pathology  
Keck School of Medicine  
University of Southern California 
Los Angeles, California
Faculty Host:  Dr. Pawel Mroz 

"Precision Genomic Medicine – Challenges, Opportunities, and a Roadmap for Effective Delivery" 

September 27

Courtney Thomas, DO 
Assistant Professor  
Department of Laboratory Medicine and Pathology  
University of Texas Health 
San Antonio, Texas 

"Updates in molecular and pathologic features of hepatocellular carcinoma"

October 4 

Goutam Charkraborty, PhD. 
Assistant Professor 
Department of Urology  
Icahn School of Medicine  
Mount Sinai 
New York, New York
Faculty Host:  Dr. Sidhartha Senn 

“Functional genomics of prostate cancer: Bedside to bench and back” 

 
October 11

Shihuan Kang, PhD  
Professor  
Department of Animal Sciences  
Interdisciplinary Life Sciences  
Purdue University  
West Lafayette, Indiana
Faculty Host:  Dr. Liam Chen  

"Lipid droplet as a key regulator of muscle stem cells and regeneration" 

October 18

Brittney Harrington, BSC, PhD 
Women’s Malignancies Branch  
National Cancer Institute  
Bethesda, Maryland
Dr. Amy Skubitz

"Using translational genomics to target ovarian cancer stem cells" 
 

October 25

Inga Hofman, MD, PhD 
Medical Director  
Program for Advanced Cell Therapy  
Academic Physician Coach  
University of Wisconsin 
Madison, Wisconsin
Faculty Host:  Dr. Michael Linden 

"What determines your level of academic and personal success - no matter what stage in your career you are at?"

November 1

Michael Farrar, PhD
Professor and Virginia and David C Utz
Land Grand Chair in Fundamental Biology 
Department of Laboratory Medicine and Pathology 
University of Minnesota Medical School 
Minneapolis, Minnesota
Faculty Host:  Dr. Sara Hamilton Hart

"Immune tolerance and leukemia relapse"


November 8

Mahmoud Khalifa, MD, PhD
Professor 
Donald F. Gleason MD, PhD 
Professorship in Surgical Pathology
Division of Anatomic Pathology 
Department of Laboratory Medicine and Pathology
University of Minnesota Medical School 
Minneapolis, Minnesota 

"Transgender pathology: Our current state"

Objectives:
1. Understanding language and terminology
2. Explore the range of expected histologic  findings
3. Emphasize impact on future screening
4. Explain laboratory administration and compliance challeng

November 15

Laura Niedernhofer, MD, PhD
Professor
Biochemistry Molecular Biology and Biophysics
College of Biological Sciences
University of Minnesota 
Minneapolis, Minnesota 
Faculty Host:  Dr. Sara Hamilton Hart 

"Geroscience approaches to extend healthspan" 

Objectives: 

1) Define Geroscience and the impetus behind this novel approach to managing the health of our aging population. 
2) Define cellular senescence and its role as a drug target  
3) Provide information about the resources provided by UMN Institute on the Biology of Aging and Metabolism to support clinical research.

November 22 – No Grand Rounds 

November 29

Marc R. Courturier, PhD
Professor 
Department of Pathology 
ARUP Laboratories
University of Utah School of Medicine 
Salt Lake City, Utah 
Faculty Host:  Dr. Patricia Ferrieri 

"Digital imaging and machine learning for stool parasite detection"

December 6 

Taylor Brown, MD
Doctoral Candidate 
Medical Science Training Program  
Department of Neuroscience  
Medical School  
University of Minnesota  
Minneapolis, Minnesota  
Faculty Host:  Dr. Liam Chen  

"GFAP+ astrocytes in the zQ175 mouse model of Huntington’s disease and their translatability in human pathology"

December 13 

Forest White, PhD 
Ned C and Janet C (Bemis) Rice Professor 
Biological Engineering  
Massachusetts Institute of Technology – MIT  
Cambridge, Massachusetts 
Faculty Host:  Dr. Kaylee Schwertferger

"Functional proteomics for clinical insight"


 

2022

January 12
Monica Sanchez-Avila, MD
Surgical Pathology Fellow
Department of Laboratory Medicine and Pathology
University of Minnesota
 
 
 
January 19
Hira Yousaf, MBBS
Cytopathology Fellow
Department of Laboratory Medicine and Pathology 
University of Minnesota 
Minneapolis, Minnesota 
 
 
 
January 26 - DEI Grand Rounds

Andrea Deyrup, MD, PhD
Professor, Department of Pathology
Director, Undergraduate Medical Education
Duke University
Durham, North Carolina

and

Joseph Graves, PhD
Professor, Biological Sciences
Department of Biology
North Carolina A & T State University
Greensboro, North Carolina

Faculty Host:  Dr. Deborah Powell

"Race in Medicine: Data or Distraction?"

 

February 2
Anna Pratt, MD
PGY 4 Resident
Department of Laboratory Medicine and Pathology
University of Minnesota
 

 

February 9
Jesse Seegmiller, PhD.
Assistant Professor
Department of Laboratory Medicine and Pathology
University of Minnesota
 
 
February 16
Stuart A. Scott, PhD
Professor, University Medical Line, Pathology
Director, Clinical Genomics Laboratory
Stanford University
Palo Alto, California
Host:  Sarah Munro, PhD
 
 
February 23
Sharon Nofec-Mozes, MD
Assistant Professor
Department of Laboratory Medicine and Pathology at Sunnybrook
University of Toronto

"Individual risk assessment for patients with DCIS: Lessons learned from the Ontario DCIS Cohort"

 

March 2
Sayak Ghatak, MBBS, PhD
PGY3, Anatomic Pathology
Department of Laboratory Medicine and Pathology
University of Minnesota
 
"HER2 del 16 and resistance to targeted therapy in CRC" (part 1, March 2, and part 2, March 30)

 

March 9
Leena Hilakivi-Clarke, PhD
Assistant Director of Research
Professor, Food Science and Nutrition
Hormel Institute
University of Minnesota
Austin, Minnesota
Hosts:  Khalil Ahmed and Janeen Trembley
 
 
March 16
Erika Pearce, PhD 
Bloomberg Distinguished Professor
Department of Molecular Microbiology and Immunology 
Bloomberg School of Public Health 
Johns Hopkins University 
Baltimore, Maryland 
Host: Ameeta Kelekar

"Mitochondrial shape-shifting in the T cell response"


 

March 30
Sayak Ghatak, MBBS, PhD, PGY3
Laboratory Medicine and Pathology
University of Minnesota
 
"HER2 del 16 and resistance to targeted therapy in CRC" (part 1, March 2, and part 2, March 30)
 
 
April 6
Tuan M. Tran, MD, PhD
Assistant Professor of Medicine
Indiana University School of Medicine
Indianapolis, Indiana
Host:  Sara Hamilton Hart
 
 
April 13
Ronald Jackups, MD, PhD
Associate Professor, Department of Pathology and Immunology
Associate CMIO, Laboratory Informatics
BJC Medical, St. Louis, Missouri
Host:  Michele Stoffel
 
 
April 20

Kamila Naxerova, PhD

Assistant Professor of Radiology
Harvard Medical School
PI, Center for Systems Biology
Massachusetts General Hospital
Boston, Massachusetts 
Host:  Ruping Sun
 
 
April 27
Professor, Laboratory Medicine and Pathology
Mayo Clinic
Rochester, Minnesota
Host:  Oyedele Adeyi, MD
 
 
 
May 4
Ling Li, PhD
Professor and VFW Endowed Chair
Experimental and Clinical Pharmacy
College of Pharmacy
University of Minnesota
Host:  Danni Li

"HDL - Good for the Heart and Good for the Mind, a lipid approach to stop the progression of Alzheimer's Disease"

 

May 11
Zohar Sachs, MD, PhD
Lois and Richard King Assistant Professor of Medicine
Division of Hematology, Oncology and Transplant
University of Minnesota Medical School
Minneapolis, MN
Host:  Jim McCarthy
 
 
 
May 18
Amy Karger, MD, PhD
Associate Professor
Laboratory Medicine and Pathology
University of Minnesota
Host:  Deborah Powell
 

 

May 25
Betsy Hirsch, PhD
Director of Cytogenetics
and Michelle Dolan, MD
Associate Director of Cytogenetics
Laboratory Medicine and Pathology
University of Minnesota

"Cytogenetic evolution: Perspectives from within" 

 

September 7

David Rimm, MD, PhD
Anthony N. Brady, Professor of Pathology and
Professor of Medicine (Medical Oncology)
Director, Yale Cancer Center Tissue Microarray Facility, Pathology
Director, Yale Pathology Tissue Services, Pathology
Director, Physician Scientist Training Program, Pathology Research
Yale University
New Haven, Connecticut

Faculty Host:  Dr. Alesio Giubellino

"Low HER2: New Drugs Need a New Assay" 

 

September 14

Juliane Gust, MD, PhD
Acting Assistant Professor
Neurosciences Center, Dept of Neurology
Seattle Children’s Hospital
University of Washington
Seattle, Washington

Host:  Christopher Pennell

Title: “CAR T cells and the brain – a dangerous dance”

 

September 21

Brian Betts, MD

Associate Professor
Division of Hematology, Oncology, and Transplantation
Department of Medicine
Medical School
University of Minnesota
Minneapolis, Minnesota

Faculty Host:  Dr. David McKenna

Title:  "Targeting CD83 to prevent GVHD and leukemia relapse after alloHCT"

 

September 28

Michael Koob, PhD

Associate Professor

Department of Laboratory Medicine and Pathology

University of Minnesota

 

Title:  "Modeling the genetics of human dementia in mice"

 

October 5

Monica Guzman, PhD
Associate Professor of Pharmacology in Medicine
Weill Cornell Medical College
New York, New York

Faculty Host:  Dr. Sidhartha Senn

"Targeting leukemia stem cells in AML"

 

October 12

Yuzhuo Wang, PhD
Distinguished Scientist and Professor
Department of Medicine
Vancouver Prostate Centre
University of British Columbia
Vancouver, Canada

Host:  Dr. Scott Dehm

"A legacy of achievements at VPC"
 

October 19

Gordana Raca, MD, PhD, FACMG

Director, Clinical Cytogenomics Laboratory, Center for Personalized Medicine

Department of Pathology and Laboratory Medicine

Children’s Hospital Los Angeles

Associate Professor of Clinical Pathology

Keck School of Medicine at the University of Southern California

Host:  Betsy Hirsch

"Utility of RNA sequencing and optical genomic mapping for comprehensive assessment of genomic abnormalities in pediatric B-lymphoblastic leukemia"

 

October 26

Sean Tracy, MD, PhD
Assistant Professor
Department of Medicine
HOT Division
Medical School
University of Minnesota
Minneapolis, Minnesota

Faculty Host:  Michael Farrar

"Relapse of acute lymphoblastic leukemia is shaped by the actions of novel CD4+ T-cell subsets"

 

November 2

Volker Witt, MD
Division of Pediatric Apheresis
Department of Pediatrics
St. Anna Kinderspital
Medical University of Vienna
Vienna, Austria

Faculty Host:  Nicole Zantek

"Apheresis in children in Vienna"

 

November 9

Fecundo Fernandez, PhD
Professor
Biochemistry and Molecular Genetics
Georgia Institute of Technology
Atlanta, Georgia

Faculty Host: Dr. Amy Skubitz

"An introduction to high resolution metabolomics for biomarker discovery"

 

November 16

Anthony Killeen, MD, MSc, PhD
Ellis S. Benson Professor and Vice Chair for Clinical Affairs
Univ of Minnesota Medical School
Minneapolis, Minnesota

“Importance of biological variation in laboratory medicine”

 

November 30

Sophia Yohe, MD, PhD
Director, Molecular Diagnostic Laboratory
Division of Hematopathology
Department of Laboratory Medicine and Pathology
University of Minnesota Medical School
Minneapolis, Minnesota

"Optical genome mapping in hematologic malignancies"

 

December 7

Anthony Demetris, MD
Starzl Professor of Liver and Transplant Pathology
Department of Pathology
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania

Faculty Host: Oyedele Adeyi

"Progress toward precision hepatic and transplant pathology"
 

December 14

Jason Sheltzer, PhD
Assistant Professor
Department of Surgery (Oncology) and Genetics
Yale University
New Haven, Connecticut

Faculty Host:  Ruping Sun

"Oncogene-like 'addictions' to aneuploidy in human cancers"

 

December 21

Annette S. Kim, MD, PhD

Associate Professor of Pathology, Associate Pathologist, Pathology
Harvard University and Brigham and Women’s Hospital
Boston, Massachusetts

Faculty Host:  Sophia Yohe 

2021

January 13 

Aimi Toyama, MD, PGYIV
Laboratory Medicine and Pathology
University of Minnesota, Twin Cities
Minneapolis, Minnesota

“PRAME and its potential in mucosal melanomas and germ cell tumors”      

 

January 20 

Ryan Martinez, MD, PhD, PGYIV
Laboratory Medicine and Pathology
University of Minnesota, Twin Cities
Minneapolis, Minnesota

“Thymic B cells in autoimmunity and cancer”

 

January 27
Beau Webber, PhD
Assistant Professor, Pediatrics 
Division of Hematology, Oncology, and Transplantation
University of Minnesota
Minneapolis, Minnesota 
Host:  David McKenna, MD

"Gene edited T cells for cancer immunotherapy"

 

February 3

Antoine Wrice, MD, PGYIV
Laboratory Medicine and Pathology
University of Minnesota, Twin Cities
Minneapolis, Minnesota

“Bias in healthcare: Implicitly explicit”

 

February 10
Eliezer Van Allen, MD
Assistant Professor & Director for Cancer Precision Medicine
Harvard Medical School
Dana Farber/Partner Care Center
Boston, Massachusettes
Faculty Host: Dr. Scott Dehm

"Computational oncology and precision cancer medicine"

 

February 17   

Yung Gong, MD
Professor, Department of Pathology/Laboratory Medicine
Division of Cytology Section
University of Texas MD Anderson Cancer Center
Houston, Texas
Faculty Host:  Dr. Faqian Li

"Strategic approach to a correct FNA diagnosis of metastatic neoplasms"

 

February 24

Pooria Koshnoodi, MD, PGYIV
Laboratory Medicine and Pathology
University of Minnesota, Twin Cities
Minneapolis, Minnesota

“The current landscape of rhabdomyosarcomas”

 
March 3

Navdeep Chandel, PhD
David W. Cugell, MD Professor
Professor of Medicine, Biochemistry and Molecular Genetics
Northwestern University
Chicago, Illinois
Faculty Host: Ameeta Kelekar, PhD

"Mitochondria control cancer and immunity"

 

March 10
Tony Ng, MD PhD 
Clinical Associate Professor | Department of Pathology and Laboratory Medicine
The University of British Columbia
Vancouver, British Columbia, CANADA 
Faculty Host:  Mahmoud Khalifa, MD, PHD
 
Title: Molecular diagnosis of sarcomas: novel methodologies and clinical implications


March 17
Andrew P. Cap, MS, MD, PhD, FACP
Colonel, Medical Corps, US Army
Director of Research, US Army Institute of Surgical Research
Hematology-Oncology Consultant to the US Army Surgeon General
NATO Blood Panel Co-Chair
Professor of Medicine, Uniformed Services University
Hematology/Oncology/BMT Staff, San Antonio Military Medical Center
San Antonio, Texas
Faculty Host:  Nicole Zantek, MD, PhD
 

 

March 24
Caleb Skipper, MD 
Fellow 
Division of Infectious Disease 
Department of Medicine 
University of Minnesota
Minneapolis, Minnesota
Faculty Host:  Patricia Ferrieri, MD

"Cytomegalovirus viremia as a risk factor for mortality in advanced HIV disease with concomitant opportunistic infections"

 

March 31      
Jin Chen, MD, PhD
Professor of Medicine, and Cell and Developmental Biology
Director of Graduate Studies in Cancer Biology
Vanderbilt School of Medicine
Vanderbilt University
Nashville, Tennessee
Faculty hosts:  Dr. Khalil Ahmed and Dr. Janeen Trembley

"Enhancing anti-tumor immunity by regulating vascular signaling and selective targeting of tumor glutamine metabolism"

 

April 7

Tiffany Hebert, MD
Associate Professor
Department of Pathology
Albert Einstein College of Medicine
Faculty Host:  Deborah Powell, MD

"Training the next generation of pathologists:  The Montefiore experience"

 

April 14

Jennifer Hunt, MD
Chair, Pathology
College of Medicine
University of Florida
Gainesville, Florida
Faculty Host:  Sophia Yohe, MD, PhD

"Women in Leadership"

 

April 21           
Betsy Hirsch, PhD
Professor, Department of Laboratory Medicine and Pathology
Director, Cancer Genomics Shared Resource
University of Minnesota Medical School
Minneapolis, Minnesota
 
Edward Anders Kolb, MD
Director - Blood & Bone Marrow Transplantation (BBMT) - HEM/ONC
Head - Cancer Therapeutics (Delaware Valley), Nemours Childrens Health System
Wilmington, Delaware

 

Todd Cooper, DO
Co-Interim Division Chief, Hematology-Oncology
Evans Family Endowed Chair in Pediatric Cancer
Seattle Children's Hospital
Seattle, Washington

"Children’s Oncology Group: Advances in clinical trials and treatment of pediatric acute myeloid leukemia"

 

April 28
Rhonda Yantiss, MD
Chief of Gastrointestinal and Liver Pathology
Weill Cornell Medical College
New York, New York
Faculty Host:  Emil Racila, MD


"The pathogenesis of coronavirus disease 2019: Insights from surgical pathologists"

 

 

May 5
Christian Martijn Schuerch, MD
Professor, Ad Interim
Senior Consultant Physician
Institute of Pathology
University Hospital of Tubingen
Tubingen, Germany

"Predicting cancer immunotherapy response by highly multiplexed tumor imaging"

 

May 12

Jan Czyzk, MD
Associate Professor
Division of Anatomic Pathology
Department of Laboratory Medicine and Pathology
University of Minnesota Medical School
Minneapolis, Minnesota 

“The role of serpinB13 in beta cell development and diabetes”

 

May 19
Sarah Bean, MD
Professor of Pathology
Clinical Sciences Department
Duke University
Raleigh, North Carolina
Faculty Hosts:  Michelle Dolan and Deborah Powell

"Just okay is not okay!  Giving and receiving feedback effectively"

 

May 26
Maha Guindi, MD
Medical Director, Digital and Telepathology
Director of GI and Liver Pathology, and Fellowship Program
Cedar Sinai Hospital, Los Angeles
Los Angeles, California
 
September 8

Lihong Bu, MD, PhD
Assistant Professor, Anatomic Pathology 
Department of Laboratory Medicine and Pathology 
Medical School, University of Minnesota 
Minneapolis, Minnesota

“The significance of glomerular galactose deficient IgA1 on kidney biopsies in patients with systemic lupus erythematosus (SLE)"

 

September 15

Stephen Jameson, PhD
Professor and Chairman’s Fund
Professorship in Experimental Pathology
Department of Laboratory Medicine and Pathology 
Medical School, University of Minnesota 
Minneapolis, Minnesota

and

Michael Koob, PhD
Associate Professor 
Department of Laboratory Medicine and Pathology 
Medical School, University of Minnesota 
Minneapolis, Minnesota

"A new mouse model for SARS-CoV-2 infection and immune response research: Modeling the 99%"

 

September 22

Douglas Strand, PhD
Assistant Professor
Department of Urology
Cancer Biology, Genetics, Development and Disease
University of Texas, Southwestern
Dallas, Texas

"A cellular anatomy of human prostate disease"

 

September 29
Jinjuan Yao, MD, PhD
Assistant Attending
Diagnostic Molecular Pathology
Department of Pathology
Memorial Sloan Kettering Cancer Center 
New York, New York

“The model of molecular diagnostics at research hospital-MSK experience”

 

October 6

Karen Choi, MD
Assistant Professor
Gastrointestinal, Hepatobiliary Pathology, Surgical Pathology
Department of Pathology
Michigan Medicine 
University of Michigan 
Ann Arbor, Michigan

“Gastric adenocarcinoma: A review and updates”

 

October 13

Kristy A. Brown, PhD
Associate Professor
Biochemistry in Medicine
Clinical and Transitional Science Center
Weill Cornell Medical College 
New York, New York

"Novel mediators of the obesity -- breast cancer link: Opportunities for intervention?"

 

October 20

Andrew Hoofnagel, MD, PhD
Head, Division of Clinical Chemistry
Department of Laboratory Medicine and Pathology 
University of Washington 
Seattle, Washington

"Proteomics: Catching flies with chopsticks"

 

October 27

Leticia Oliveira-Ferrer, PhD
Institute of Anatomy
University Hospital – Eppendorf
Hamburg, Germany

“Mechanisms of ovarian cancer progression:  Tumor heterogeneity and the role of ascites-derived tumor cells”

 

November 3

Molly Klein, MD
Assistant Professor
Department of Laboratory Medicine and Pathology
University of Minnesota 
Minneapolis, Minnesota

"Neoadjuvant therapy for breast carcinoma: Evaluation of inter-regimen breast biopsies to identify candidates for de-escalation of therapy"

 

November 10
Elizabeth Anne Montgomery, MD
Professor of Pathology
Vice Chair, Anatomic Pathology
University of Miami Miller School of Medicine
Miami, Florida

“Gastrointestinal tract mesenchymal neoplasms – Location is Everything”

 

November 17
Christopher Mason, PhD
Professor of Physiology and Biophysics
Weill Cornell Medicine
New York, New York
Host:  Sarah Munro, PhD
 
 
 
November 24 

Thanksgiving Holiday

 

December 1 
James Modiano, VMD, PhD
Perlman Professor of Oncology and Comparative Medicine
Director, Animal Cancer Care and Research Program
College of Veterinary Medicine and Masonic Cancer Center
University of Minnesota
 

“One pathologist’s dream:  Detecting cancer before it starts, and killing it before it forms”

 

December 8
Nicole Cipriani, MD
Associate Professor
Head and Neck Cancer
Department of Pathology
University of Chicago
Chicago, Illinois

"Where have all the cancers gone? Diagnostic dilemmas in follicular-patterned thyroid neoplasms"

 

December 15

Jonathan Kirk, PhD
Associate Professor 
Department of Cell and Molecular Physiology 
Director, Loyola Proteomics Core
Stritch School of Medicine 
Loyola University 
Maywood, Illinois

“Cardiac sarcomere protein quality control and BAG3: Repairing the engine without stopping the car”

 

2020

January 8

Saar I Gill, MD, PhD
Assistant Professor of Medicine
Hospital of the University of Pennsylvania
Perelman School of Medicine
Philadelphia, Pennsylvania

"CAR-T cells 2020"

January 15

Anthony A.  Killeen, MD, PhD
Ellis S. Benson Professor
Director, Clinical Laboratories
Vice Chair for Clinical Affairs
Department of Laboratory Medicine and Pathology
University of Minnesota - TC

"Using large clinical laboratory datasets to study biological variation"

January 22

Mahmoud Khalifa, MD, PhD
Professor and Donald F. Gleason MD, PhD Professorship in Surgical Pathology
Director, Anatomic Pathology
Department of Laboratory Medicine and Pathology
University of Minnesota - TC

"Endometrial cancer pathology: An evolutionary story"

January 29

Bartosz Grzywacz, MD
Assistant Professor
Division of Hematopathology
Department of Laboratory Medicine and Pathology
University of Minnesota - TC

"Clinical and research studies on Natural Killer cells in hematopathology and immunotherapy"

 

February 5

*CANCELLED*

Meaghan Hupp, MD
PGY IV
Department of Laboratory Medicine and Pathology
University of Minnesota - TC
 
"College of American Pathologists Proficiency Testing and Laboratory Accreditation Program"

February 12

Sara Hamilton Hart, PhD
Assistant Professor 
Department of Laboratory Medicine and Pathology
University of Minnesota - TC

"Prevention of cerebral pathology during severe malaria"

February 19

Aastha Chauhan, MD
PGYIV
Department of Laboratory Medicine and Pathology
University of Minnesota - TC

"Role of cytology cell blocks for PD-L1 testing in advanced non-small cell lung carcinoma: An institutional experience"

February 26

Huihui Ye, MD, MS
Clinical Associate Professor
Chief, Genitourinary Pathology
Pathology and Laboratory Medicine
David Geffen School of Medicine
University of California, Los Angeles
Los Angeles, California

"Pathology of genitourinary tumors in the era of molecular medicine"

 

March 4

Robert Bast, Jr., MD
Vice President for Translational Research
Internist and Professor of Medicine
Department of Experimental Therapeutics
Division of Cancer Medicine
University of Texas MD Anderson Cancer Center
Houston, Texas

"Early detection of ovarian cancer:  An update"

March 11

Dina Greene, PhD
Technical Director, Kaiser Washington Laboratories 
Clinical Associate Professor 
University of Washington
Seattle, Washington 
 
"Breaking down gender for cis to trans"

March 18

Luis A. Ortiz, MD
Professor, Environmental and Occupational Health, Department of Medicine
and Clinical and Translational Science Institute
Pitt Public Health
Pittburgh, Pennsylvania
 
"Of vesicles and right ventricles: How MSC improve pulmonary fibrosis" 

March 25  *CANCELLED*

Navdeep S. Chandel, PhD
David W. Cugell MD, Professor
Professor of Medicine and Biochemistry and Molecular Genetics
Feinberg School of Medicine
Northwestern Medicine
Northwestern University
Chicago, Illinois
 
 

April 1 - *NOTE* - All Grand Rounds will be presented via Zoom. 

Claudia S. Cohn, MD, PhD
Associate Professor, Laboratory Medicine and Pathology 
Director, Blood Bank Laboratory 
Associate Director, Clinical Laboratories
University of Minnesota Medical School 
Minneapolis, Minnesota 
 

 

April 8 

Gerald Berry, MD
Professor of Pathology
Stanford University Medical Center
Stanford, California

"Giant Cell Arteritis: What have we learned about the pathogenesis"

   

April 15 

Jeremy Segal, MD, PhD
Associate Professor of Pathology
The University of Chicago
Chicago, Illinois

"A multi-institutional collaborative effort to drive cost reduction and standardization of academic oncology next generation sequencing diagnostics"  

 

April 22 - *CANCELLED*

Chunhai Hao, MD, PhD
Bicentennial Professor of Pathology and Laboratory Medicine
Indiana University School of Medicine
Indianapolis, Indiana

 

April 29

Adam Bagg, MD
Professor of Pathology and Laboratory Medicine
Perelman School of Medicine
University of Pennsylvania
Philadelphia, Pennsylvania 

“B-cells behaving badly: A better basis to behold belligerence in small B-cell lymphomas”

 

May 6 

Laura Lamps, MD
Godfrey Dorr Stobbe Professor and Director
Gastrointestinal Pathology
Patient Safety Officer
Department of Pathology
Michigan Medicine
University of Michigan
Ann Arbor, Michigan  

 
"Emerging Infections: historical perspectives, precipitating factors, and pathologic diagnosis" 

 

May 13 

Ameeta Kelekar, PhD
Associate Professor
Department of Laboratory Medicine and Pathology
University of Minnesota Medical School - TC

"Reprogramming immune- and cancer-cell metabolism with small proteins and metabolites"   

 

May 20

Raouf Nakhleh, MD
Professor of Pathology
Mayo Clinic
Jacksonville, Florida  

"Evidence Based Laboratory Practice Guidelines"

 

May 27

David Parham, MD
Chief, Director and Professor
Department of Pathology and Laboratory Medicine
Keck School of Medicine
University of Southern California
Los Angeles, California 

"Rhabdomyosarcoma: from obscurity to clarity in diagnosis and classification"

September 9

Hooman Rashidi, MD
Professor and Vice Chair, GME
Director of Flow Cytology and Immunology
Sacramento, California
Faculty Host:  Dr. Sarah Williams

"Automated machine learning & the introduction of MILO (Machine Intelligence Learning Optimizer)"

September 16

Meghan Hupp, MD
Fellow, Division of Hematopathology
University of Minnesota
Minneapolis, Minnesota

"College of American Pathologists Proficiency Testing and Laboratory Accreditation Program"  

 
September 23

Laurie Littlepage, PhD
Associate Professor
Department of Chemistry and Biochemistry
University of Notre Dame
Notre Dame, Indianna
Faculty Host:  Dr. Kaylee Schwertferger

"Tumor metabolism and chemokine signaling as vulnerabilities of breast cancer metastasis"

 

September 30

Hua Zhu, PhD
Associate Professor
Department of  Microbiology, Biochemistry
   and Molecular Genetics
Rutgers University
Newark, New Jersey
Faculty Host:  Dr. Faqian Li

"Plasma membrane damage repair in myocardium injury"

 

October 7

Susan Carole Lester, MD, PhD
Assistant Professor of Pathology
Brigham and Women’s Hospital
Boston, Massachusetts
Faculty Host:  Dr. Emil Racilla

"Spindle cell lesions of the breast: Avoiding perilous pitfalls"

 
October 14

Hilary Kenny, PhD
Research Associate Professor
Department of Obstetrics and Gynecology
University of Chicago
Chicago, Illinois
Faculty Host:  Dr. Amy Skubitz

 
October 21

Jaclyn Biegel, PhD
Professor of Pathology
Chief of Genomic Medicine
Center for Personalized Medicine
Keck School of Medicine, USC
Los Angeles, California
Faculty Host:  Dr. Betsy Hirsch

"Genetic predisposition to pediatric solid tumors" 

 
October 28 
Eileen Crimmins, PhD
University Professor
AARP Chair in Gerontology
Director, Multidisciplinary Research Training in Gerontology PhD Program
School of Gerontology
USC Davis
Los Angeles, California
Faculty Host:  Dr. Bharat Thyagarajan

"Social, psychological, behavioral and biological risks for aging health: Evidence from the US Health and Retirement Study"

  

November 4

Richard Kaufman, MD
Medical Director, Adult Transfusion
Brigham and Women’s Hospital
Boston, Massachusetts
Faculty Host:  Dr. Claudia S. Cohn

"Severe CD4 lymphopenia in frequent platelet donors"  

  

November 11

Hui Zhu, MD
Department of Urology
Cleveland Clinic
Warrensville Heights, Ohio
Faculty Host:  Dr. Faqian Li

"Head and neck neoplasms masquerading as squamous cell carcinoma"

 

November 18

Danny Welch, PhD
Professor
Department of Molecular and Integrative Physiology
The University of Kansas
Kansas City, Kansas
Faculty Host:  Dr. James McCarthy

"Mitochondrial polymorphisms as contributors to metastasis"

 

November 25

No Grand Rounds
Thanksgiving Break

 

December 2

Amanda Paulovich, MD, PhD
Professor, Clinical Research Division
Fred Hutch
Seattle, Washington
Faculty Host:  Dr. Stefani Thomas

"Developing MRM assays for the translation of novel diagnostics and therapeutics to enable precision medicine"

 

December 9

Adolfo Garcia Ocana, PhD
Dept of Medicine, Endocrinology, Diabetes
  and Bone Disease
Icahn School of Medicine at Mt. Sinai
New York, New York
Faculty Host:  Dr. Jan Czyzk

"Regeneration and preservation of pancreatic beta cells for diabetes"

 

December 16

Laura Su, MD, PhD
Assistant Professor of Medicine
Perelman School of Medicine
University of Pennsylvania
Philadelphia, Pennsylvania
Faculty Host:  Dr. Sara Hamilton

"The ghost of immunological memory past, present, and future"