Arthur Leuthold, PhD

Assistant Professor, Department of Neuroscience

Arthur Leuthold

Contact Info

leuth004@umn.edu

Office Phone 612-725-2000 x5546

Office Address:
Brain Sciences Center VA Medical Center

Assistant Professor, Department of Neuroscience


Research

Research Summary/Interests

Magnetocardiography studies

Dr. Leuthold's research involves the use of magnetocardiography to study cardiac physiology and abnormalities.

In a recent study, fetal cardiac waveform intervals were assessed from fetal magnetocardiogram (FMCG) recordings taken from pregnant women at 17-41 weeks gestation. Correlations with gestational age were found for PR interval and QRS interval. Abnormal waveform morphology was documented in several patients with cardiac malformations. 

Another study focused on atrial and ventricular fetal heart rate patterns in isolated congenital complete heart block detected by magnetocardiography. Atrial and ventricular fetal heart rate tracings from a patient with isolated congenital complete heart block treated with dexamethasone showed a remarkable degree of correlation and greater reactivity for the ventricular than the atrial fetal heart rate. Ventriculophasic sinus arrhythmia was present continually in the atrial fetal heart rate tracings.

Publications

James, LM, Dolan, S, Leuthold, AC, Engdahl, BE, Georgopoulos, A & Georgopoulos, AP 2018, ‘The effects of human leukocyte antigen DRB1*13 and apolipoprotein E on age-related variability of synchronous neural interactions in healthy women’ EBioMedicine, vol. 35 pp. 288-294. https://doi.org/10.1016/j.ebiom.2018.08.026

Engdahl, BE, James, LM, Miller, RD, Leuthold, AC, Lewis, SM, Carpenter, AF & Georgopoulos, AP 2018, ‘Brain Function in Gulf War Illness (GWI) and Associated Mental Health Comorbidities’ J Neurol Neuromedicine, vol. 3, no. 4, pp. 24-34.

Georgopoulos, AP, James, LM, Carpenter, AF, Engdahl, BE, Leuthold, AC & Lewis, SM 2017, ‘Gulf War illness (GWI) as a neuroimmune disease’ Exp Brain Res, vol. 235, no. 10, pp. 3217-3225. https://doi.org/10.1007/s00221-017-5050-0

Engdahl, BE, James, LM, Miller, RD, Leuthold, AC, Lewis, SM, Carpenter, AF & Georgopoulos, AP 2016, ‘A Magnetoencephalographic (MEG) Study of Gulf War Illness (GWI)’ EBioMedicine, vol. 12, pp. 127-132. https://doi.org/10.1016/j.ebiom.2016.08.030

James, LM, Engdahl, BE, Leuthold, AC & Georgopoulos, AP 2016, ‘Brain Correlates of Human Leukocyte Antigen (HLA) Protection in Gulf War Illness (GWI)’ EBioMedicine, vol. 13, pp. 72-79. https://doi.org/10.1016/j.ebiom.2016.10.019

Lewis, SM, Vydrová, RR, Leuthold, AC & Georgopoulos, AP 2016, ‘Cortical miscommunication after prenatal exposure to alcohol’ Exp Brain Res, vol. 234, no. 11, pp. 3347-3353. https://doi.org/10.1007/s00221-016-4732-3

James, LM, Engdahl, BE, Leuthold, AC, Krueger, RF & Georgopoulos, AP 2015, ‘Pathological personality traits modulate neural interactions’ Exp Brain Res, vol. 233, no. 12, pp. 3543-52. https://doi.org/10.1007/s00221-015-4406-6

Sakellaridi, S, Christova, P, Christopoulos, V, Leuthold, AC, Peponis, J & Georgopoulos, AP 2015, ‘Neural mechanisms underlying the exploration of small city maps using magnetoencephalography’ Exp Brain Res, vol. 233, no. 11, pp. 3187-200. https://doi.org/10.1007/s00221-015-4387-5

James, LM, Belitskaya-Lévy, I, Lu, Y, Wang, H, Engdahl, BE, Leuthold, AC & Georgopoulos, AP 2015, ‘Development and application of a diagnostic algorithm for posttraumatic stress disorder’ Psychiatry Res, vol. 231, no. 1, pp. 1-7. https://doi.org/10.1016/j.pscychresns.2014.11.007

Tan, H-RM, Leuthold, AC, Lee, DN, Lynch, JK & Georgopoulos, AP 2009, ‘Neural mechanisms of movement speed and tau as revealed by magnetoencephalography’ Exp Brain Res, vol. 195, no. 4, pp. 541-52. https://doi.org/10.1007/s00221-009-1822-5